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indoleacetic acid and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

indoleacetic acid has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 1 studies

indoleacetic acid: RN given refers to unlabeled parent cpd; structure in Merck Index, 9th ed, #4841
auxin : Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow").
indole-3-acetic acid : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a 1H-indol-3-yl group.

Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.

Research Excerpts

ExcerptRelevanceReference
"To investigate the possible mechanism of apoptosis induced by indole-3-acetic acid (IAA) combined with horseradish peroxidase in leukemia cell line K562, cell proliferation and apoptosis of K562 cell were examined by MTT assay and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL), respectively; the activity of superoxide dismutase (SOD) and the quantitative change of MDA were measured by biochemical method; changes of free radical were determined by 2, 7-dichlorofluorescin diacetate (DCFH-DA) probe with confocal microscopy."1.33[Mechanism of apoptosis induced by indole-3-acetic acids combined with horseradish peroxidase in leukemia cell line K562]. ( Huang, C; Liu, LY; Luo, Y; Ni, L; Si, LS; Song, TS; Yang, L, 2005)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, L1
Song, TS1
Huang, C1
Liu, LY1
Luo, Y1
Ni, L1
Si, LS1

Other Studies

1 other study available for indoleacetic acid and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

ArticleYear
[Mechanism of apoptosis induced by indole-3-acetic acids combined with horseradish peroxidase in leukemia cell line K562].
    Zhongguo shi yan xue ye xue za zhi, 2005, Volume: 13, Issue:5

    Topics: Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Hors

2005