Page last updated: 2024-10-18

indoleacetic acid and Kidney Failure, Chronic

indoleacetic acid has been researched along with Kidney Failure, Chronic in 8 studies

indoleacetic acid: RN given refers to unlabeled parent cpd; structure in Merck Index, 9th ed, #4841
auxin : Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow").
indole-3-acetic acid : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a 1H-indol-3-yl group.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"Thus, progression of chronic renal failure may be promoted by PAI-1 up-regulation induced by uremic toxins."1.32Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-kappaB and free radical in proximal tubular cells. ( Hosokawa, A; Motojima, M; Muraki, T; Yamato, H; Yoshioka, T, 2003)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Meibaum, J1
Krause, S1
Hillmer, H1
Marcelli, D1
Strohhöfer, C1
Paats, J1
Adoberg, A1
Arund, J1
Dhondt, A1
Fernström, A1
Fridolin, I1
Glorieux, G1
Leis, L1
Luman, M1
Gonzalez-Parra, E1
Perez-Gomez, VM1
Pilt, K1
Sanchez-Ospina, D1
Segelmark, M1
Uhlin, F1
Arduan Ortiz, A1
Yamamoto, S1
Sato, M1
Sato, Y1
Wakamatsu, T1
Takahashi, Y1
Iguchi, A1
Omori, K1
Suzuki, Y1
Ei, I1
Kaneko, Y1
Goto, S1
Kazama, JJ1
Gejyo, F1
Narita, I1
Lin, YT1
Wu, PH1
Lee, HH1
Mubanga, M1
Chen, CS1
Kuo, MC1
Chiu, YW1
Kuo, PL1
Hwang, SJ1
Tsujimoto, M1
Nagano, Y1
Hosoda, S1
Shiraishi, A1
Miyoshi, A1
Hiraoka, S1
Furukubo, T1
Izumi, S1
Yamakawa, T1
Minegaki, T1
Nishiguchi, K1
Calaf, R1
Cerini, C1
Génovésio, C1
Verhaeghe, P1
Jourde-Chiche, N1
Bergé-Lefranc, D1
Gondouin, B1
Dou, L1
Morange, S1
Argilés, A1
Rathelot, P1
Dignat-George, F1
Brunet, P1
Charpiot, P1
Chitalia, VC1
Shivanna, S1
Martorell, J1
Balcells, M1
Bosch, I1
Kolandaivelu, K1
Edelman, ER1
Motojima, M1
Hosokawa, A1
Yamato, H1
Muraki, T1
Yoshioka, T1

Trials

1 trial available for indoleacetic acid and Kidney Failure, Chronic

ArticleYear
Adsorption of Protein-Bound Uremic Toxins Through Direct Hemoperfusion With Hexadecyl-Immobilized Cellulose Beads in Patients Undergoing Hemodialysis.
    Artificial organs, 2018, Volume: 42, Issue:1

    Topics: Adsorption; Aged; Blood Proteins; Cellulose; Cresols; Feasibility Studies; Female; Hemoperfusion; Hu

2018

Other Studies

7 other studies available for indoleacetic acid and Kidney Failure, Chronic

ArticleYear
Identification and characterisation of fluorescent substances in spent dialysis fluid.
    The International journal of artificial organs, 2020, Volume: 43, Issue:9

    Topics: Chromatography, High Pressure Liquid; Dialysis Solutions; Humans; Indican; Indoleacetic Acids; Kidne

2020
Serum Levels and Removal by Haemodialysis and Haemodiafiltration of Tryptophan-Derived Uremic Toxins in ESKD Patients.
    International journal of molecular sciences, 2020, Feb-23, Volume: 21, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Female; Hemodiafiltration; Humans; Indican; Indoleacetic Acids; Kidn

2020
Indole-3 acetic acid increased risk of impaired cognitive function in patients receiving hemodialysis.
    Neurotoxicology, 2019, Volume: 73

    Topics: Aged; Biomarkers; Blood-Brain Barrier; Brain; Capillary Permeability; Cognition; Cognitive Dysfuncti

2019
Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease.
    Toxins, 2013, Aug-19, Volume: 5, Issue:8

    Topics: Cell Line, Tumor; Cytochrome P-450 CYP3A; Erythromycin; Furans; Hippurates; Humans; Indican; Indolea

2013
Determination of uremic solutes in biological fluids of chronic kidney disease patients by HPLC assay.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Aug-01, Volume: 879, Issue:23

    Topics: Aged; Chromatography, High Pressure Liquid; Cresols; Female; Humans; Indican; Indoleacetic Acids; Ki

2011
Uremic serum and solutes increase post-vascular interventional thrombotic risk through altered stability of smooth muscle cell tissue factor.
    Circulation, 2013, Jan-22, Volume: 127, Issue:3

    Topics: Adult; Aged; Cell Line; Coronary Vessels; Endothelium, Vascular; Female; Humans; In Vitro Techniques

2013
Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-kappaB and free radical in proximal tubular cells.
    Kidney international, 2003, Volume: 63, Issue:5

    Topics: Anions; Cells, Cultured; Free Radicals; Gene Expression; Humans; Indican; Indoleacetic Acids; Kidney

2003