Page last updated: 2024-10-18

indoleacetic acid and Inflammation

indoleacetic acid has been researched along with Inflammation in 8 studies

indoleacetic acid: RN given refers to unlabeled parent cpd; structure in Merck Index, 9th ed, #4841
auxin : Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow").
indole-3-acetic acid : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a 1H-indol-3-yl group.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"Adults with chronic kidney disease (CKD) exhibit alterations in tryptophan metabolism, mainly via the kynurenine pathway, due to higher enzymatic activity induced mainly by inflammation."7.83Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study. ( Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA, 2016)
"Adults with chronic kidney disease (CKD) exhibit alterations in tryptophan metabolism, mainly via the kynurenine pathway, due to higher enzymatic activity induced mainly by inflammation."3.83Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study. ( Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA, 2016)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Ji, Y1
Gao, Y1
Chen, H1
Yin, Y1
Zhang, W1
Olivier, V1
Dunyach-Remy, C1
Corbeau, P1
Cristol, JP1
Sutra, T1
Burtey, S1
Lavigne, JP1
Moranne, O1
Chowdhury, MMI1
Kurata, K1
Yuasa, K1
Koto, Y1
Nishimura, K1
Shimizu, H1
Krishnan, S1
Ding, Y1
Saedi, N1
Choi, M1
Sridharan, GV1
Sherr, DH1
Yarmush, ML1
Alaniz, RC1
Jayaraman, A1
Lee, K1
Kim, DC1
Quang, TH1
Yoon, CS1
Ngan, NTT1
Lim, SI1
Lee, SY1
Kim, YC1
Oh, H1
Segal, LN1
Clemente, JC1
Wu, BG1
Wikoff, WR1
Gao, Z1
Li, Y1
Ko, JP1
Rom, WN1
Blaser, MJ1
Weiden, MD1
Karu, N1
McKercher, C1
Nichols, DS1
Davies, N1
Shellie, RA1
Hilder, EF1
Jose, MD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Chronic Obstructive Pulmonary Disease Transcription Factor and Cytokine Study[NCT02557958]Early Phase 119 participants (Actual)Interventional2009-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for indoleacetic acid and Inflammation

ArticleYear
Randomised, double-blind, placebo-controlled trial with azithromycin selects for anti-inflammatory microbial metabolites in the emphysematous lung.
    Thorax, 2017, Volume: 72, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Azithromycin; Bronchoalveolar Lavage Fluid; Chemokine CXCL1; Cytokines;

2017

Other Studies

7 other studies available for indoleacetic acid and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Indole-3-Acetic Acid Alleviates Nonalcoholic Fatty Liver Disease in Mice via Attenuation of Hepatic Lipogenesis, and Oxidative and Inflammatory Stress.
    Nutrients, 2019, Sep-03, Volume: 11, Issue:9

    Topics: Animals; Indoleacetic Acids; Inflammation; Lipids; Lipogenesis; Liver; Male; Mice; Mice, Inbred C57B

2019
Factors of microinflammation in non-diabetic chronic kidney disease: a pilot study.
    BMC nephrology, 2020, 04-21, Volume: 21, Issue:1

    Topics: Bacterial Translocation; Biomarkers; C-Reactive Protein; Female; Gastrointestinal Microbiome; Humans

2020
Suppression of TNFα expression induced by indole-3-acetic acid is not mediated by AhR activation in Caco-2 cells.
    Bioscience, biotechnology, and biochemistry, 2021, Mar-24, Volume: 85, Issue:4

    Topics: Caco-2 Cells; Humans; Indoleacetic Acids; Inflammation; Receptors, Aryl Hydrocarbon; Tumor Necrosis

2021
Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages.
    Cell reports, 2018, 04-24, Volume: 23, Issue:4

    Topics: Animals; Cytokines; Dietary Fats; Fatty Acid Synthase, Type I; Gastrointestinal Microbiome; Hep G2 C

2018
Anti-neuroinflammatory activities of indole alkaloids from kanjang (Korean fermented soy source) in lipopolysaccharide-induced BV2 microglial cells.
    Food chemistry, 2016, Dec-15, Volume: 213

    Topics: Animals; Anti-Inflammatory Agents; Carbolines; Cell Nucleus; Cell Survival; Cyclooxygenase 2; Cytoso

2016
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study.
    BMC nephrology, 2016, 11-10, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Anxiety; Biomarkers; Cognition; Cross-Sectional Studies; Depression; Female

2016