Page last updated: 2024-10-18

indoleacetic acid and Disease Models, Animal

indoleacetic acid has been researched along with Disease Models, Animal in 11 studies

indoleacetic acid: RN given refers to unlabeled parent cpd; structure in Merck Index, 9th ed, #4841
auxin : Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow").
indole-3-acetic acid : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a 1H-indol-3-yl group.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Ulcerative colitis has been consistently associated with gut microbiota imbalance and disturbed immune system."1.91Gut Bacterial Indole-3-acetic Acid Induced Immune Promotion Mediates Preventive Effects of Fu Brick Tea Polyphenols on Experimental Colitis. ( Han, N; Li, Q; Ren, D; Shi, L; Wang, N; Yan, T; Yang, X; Zhang, B; Zhang, L; Zhang, X; Zhao, Y, 2023)
"Growth of hepatoma xenografts, including the size and weight, was inhibited in mice treated with pAdv-AFP-HRPC and IAA, compared with that in control group."1.38Tumor-targeted gene therapy using Adv-AFP-HRPC/IAA prodrug system suppresses growth of hepatoma xenografted in mice. ( Chen, DE; Dai, M; Dong, CY; Ho, WZ; Liu, J; Rao, Y; Tang, ZJ, 2012)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's4 (36.36)24.3611
2020's6 (54.55)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Vial, R1
Poitevin, S1
McKay, N1
Burtey, S1
Cerini, C1
Zhang, X1
Shi, L1
Wang, N1
Li, Q1
Zhang, L1
Han, N1
Yan, T1
Ren, D1
Zhang, B1
Zhao, Y1
Yang, X1
Tintelnot, J1
Xu, Y2
Lesker, TR1
Schönlein, M1
Konczalla, L1
Giannou, AD1
Pelczar, P1
Kylies, D1
Puelles, VG1
Bielecka, AA1
Peschka, M1
Cortesi, F1
Riecken, K1
Jung, M1
Amend, L1
Bröring, TS1
Trajkovic-Arsic, M1
Siveke, JT1
Renné, T1
Zhang, D1
Boeck, S1
Strowig, T1
Uzunoglu, FG1
Güngör, C1
Stein, A1
Izbicki, JR1
Bokemeyer, C1
Sinn, M1
Kimmelman, AC1
Huber, S1
Gagliani, N1
Li, K1
Hao, Z1
Du, J1
Gao, Y1
Yang, S1
Zhou, Y2
Liu, Y1
Yang, K1
Jia, Y1
Shi, J1
Tong, Z1
Fang, D1
Yang, B1
Su, C1
Li, R1
Xiao, X1
Wang, Z1
Wilck, N1
Matus, MG1
Kearney, SM1
Olesen, SW1
Forslund, K1
Bartolomaeus, H1
Haase, S1
Mähler, A1
Balogh, A1
Markó, L1
Vvedenskaya, O1
Kleiner, FH1
Tsvetkov, D1
Klug, L1
Costea, PI1
Sunagawa, S1
Maier, L1
Rakova, N1
Schatz, V1
Neubert, P1
Frätzer, C1
Krannich, A1
Gollasch, M1
Grohme, DA1
Côrte-Real, BF1
Gerlach, RG1
Basic, M1
Typas, A1
Wu, C1
Titze, JM1
Jantsch, J1
Boschmann, M1
Dechend, R1
Kleinewietfeld, M1
Kempa, S1
Bork, P1
Linker, RA1
Alm, EJ1
Müller, DN1
Lee, W1
Lee, J1
Kulkarni, R1
Kim, MA1
Hwang, JS1
Na, M1
Bae, JS1
Hou, J1
Liu, Z1
Yu, H1
Sun, W1
Xiong, J1
Liao, Z1
Zhou, F1
Xie, C1
Dai, M1
Liu, J1
Chen, DE1
Rao, Y1
Tang, ZJ1
Ho, WZ1
Dong, CY1
Folkes, LK1
Greco, O1
Dachs, GU1
Stratford, MR1
Wardman, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Probiotics on Grade 1 Primary Hypertension and Prehypertension and the Underlying Mechanism: a Randomized Controlled Trial[NCT05095350]Early Phase 1115 participants (Actual)Interventional2021-12-05Completed
Effects of Increased Salt Intake on Metabolic, Cardiovascular and Immunoregulatory Functions in Healthy Men[NCT02509962]14 participants (Actual)Interventional2015-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

11 other studies available for indoleacetic acid and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Tryptophan Metabolites Regulate Neuropentraxin 1 Expression in Endothelial Cells.
    International journal of molecular sciences, 2022, Feb-21, Volume: 23, Issue:4

    Topics: Animals; C-Reactive Protein; Carbazoles; Cells, Cultured; Disease Models, Animal; Human Umbilical Ve

2022
Gut Bacterial Indole-3-acetic Acid Induced Immune Promotion Mediates Preventive Effects of Fu Brick Tea Polyphenols on Experimental Colitis.
    Journal of agricultural and food chemistry, 2023, Jan-18, Volume: 71, Issue:2

    Topics: Animals; Bacteria; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gas

2023
Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer.
    Nature, 2023, Volume: 615, Issue:7950

    Topics: Animals; Autophagy; Carcinoma, Pancreatic Ductal; Disease Models, Animal; Fecal Microbiota Transplan

2023
Bacteroides thetaiotaomicron relieves colon inflammation by activating aryl hydrocarbon receptor and modulating CD4
    International immunopharmacology, 2021, Volume: 90

    Topics: Animals; Bacteroides thetaiotaomicron; Basic Helix-Loop-Helix Transcription Factors; Cell Differenti

2021
Gut microbiome alterations in high-fat-diet-fed mice are associated with antibiotic tolerance.
    Nature microbiology, 2021, Volume: 6, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Bacterial Load; Diet, High-Fat; Disease Models

2021
Salt-responsive gut commensal modulates T
    Nature, 2017, 11-30, Volume: 551, Issue:7682

    Topics: Animals; Autoimmunity; Blood Pressure; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experi

2017
Salt-responsive gut commensal modulates T
    Nature, 2017, 11-30, Volume: 551, Issue:7682

    Topics: Animals; Autoimmunity; Blood Pressure; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experi

2017
Salt-responsive gut commensal modulates T
    Nature, 2017, 11-30, Volume: 551, Issue:7682

    Topics: Animals; Autoimmunity; Blood Pressure; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experi

2017
Salt-responsive gut commensal modulates T
    Nature, 2017, 11-30, Volume: 551, Issue:7682

    Topics: Animals; Autoimmunity; Blood Pressure; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experi

2017
Antithrombotic and antiplatelet activities of small-molecule alkaloids from Scolopendra subspinipes mutilans.
    Scientific reports, 2016, Feb-24, Volume: 6

    Topics: Acylation; Alkaloids; Animals; Anticoagulants; Disease Models, Animal; Diterpene Alkaloids; Drug Dis

2016
Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma.
    Journal of translational medicine, 2011, Apr-11, Volume: 9

    Topics: Adenoviridae; Animals; Apoptosis; Biomarkers, Tumor; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell P

2011
Tumor-targeted gene therapy using Adv-AFP-HRPC/IAA prodrug system suppresses growth of hepatoma xenografted in mice.
    Cancer gene therapy, 2012, Volume: 19, Issue:2

    Topics: Adenoviridae; alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Cell Growth Processes; Cell Li

2012
5-Fluoroindole-3-acetic acid: a prodrug activated by a peroxidase with potential for use in targeted cancer therapy.
    Biochemical pharmacology, 2002, Jan-15, Volume: 63, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Survival; Disease Models, Animal; Drug Delivery Systems; Female

2002