indoleacetic acid has been researched along with Chronic Kidney Diseases in 28 studies
indoleacetic acid: RN given refers to unlabeled parent cpd; structure in Merck Index, 9th ed, #4841
auxin : Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow").
indole-3-acetic acid : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a 1H-indol-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adults with chronic kidney disease (CKD) exhibit alterations in tryptophan metabolism, mainly via the kynurenine pathway, due to higher enzymatic activity induced mainly by inflammation." | 7.83 | Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study. ( Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA, 2016) |
| "Adults with chronic kidney disease (CKD) exhibit alterations in tryptophan metabolism, mainly via the kynurenine pathway, due to higher enzymatic activity induced mainly by inflammation." | 3.83 | Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study. ( Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 17 (60.71) | 24.3611 |
| 2020's | 9 (32.14) | 2.80 |
| Authors | Studies |
|---|---|
| Steenbeke, M | 1 |
| Valkenburg, S | 1 |
| Gryp, T | 2 |
| Van Biesen, W | 4 |
| Delanghe, JR | 1 |
| Speeckaert, MM | 1 |
| Glorieux, G | 9 |
| Cernaro, V | 1 |
| Calabrese, V | 1 |
| Loddo, S | 1 |
| Corsaro, R | 1 |
| Macaione, V | 1 |
| Ferlazzo, VT | 1 |
| Cigala, RM | 1 |
| Crea, F | 1 |
| De Stefano, C | 1 |
| Gembillo, G | 1 |
| Romeo, A | 1 |
| Longhitano, E | 1 |
| Santoro, D | 1 |
| Buemi, M | 1 |
| Benvenga, S | 1 |
| Vial, R | 1 |
| Poitevin, S | 4 |
| McKay, N | 3 |
| Burtey, S | 6 |
| Cerini, C | 4 |
| Paats, J | 1 |
| Adoberg, A | 1 |
| Arund, J | 1 |
| Dhondt, A | 3 |
| Fernström, A | 1 |
| Fridolin, I | 1 |
| Leis, L | 1 |
| Luman, M | 1 |
| Gonzalez-Parra, E | 1 |
| Perez-Gomez, VM | 1 |
| Pilt, K | 1 |
| Sanchez-Ospina, D | 1 |
| Segelmark, M | 1 |
| Uhlin, F | 1 |
| Arduan Ortiz, A | 1 |
| Huys, GRB | 1 |
| Joossens, M | 1 |
| Vaneechoutte, M | 1 |
| Liabeuf, S | 3 |
| Laville, SM | 1 |
| Cheddani, L | 1 |
| Brazier, F | 1 |
| Titeca Beauport, D | 1 |
| Valholder, R | 1 |
| Choukroun, G | 2 |
| Massy, ZA | 2 |
| Olivier, V | 1 |
| Dunyach-Remy, C | 1 |
| Corbeau, P | 1 |
| Cristol, JP | 1 |
| Sutra, T | 1 |
| Lavigne, JP | 1 |
| Moranne, O | 1 |
| Liu, JR | 1 |
| Miao, H | 1 |
| Deng, DQ | 1 |
| Vaziri, ND | 1 |
| Li, P | 1 |
| Zhao, YY | 1 |
| Yamamoto, S | 1 |
| Sasahara, K | 1 |
| Domon, M | 1 |
| Yamaguchi, K | 1 |
| Ito, T | 1 |
| Goto, S | 1 |
| Goto, Y | 1 |
| Narita, I | 1 |
| Brito, JS | 1 |
| Borges, NA | 1 |
| Esgalhado, M | 1 |
| Magliano, DC | 1 |
| Soulage, CO | 1 |
| Mafra, D | 2 |
| Deltombe, O | 3 |
| de Loor, H | 1 |
| Meijers, B | 1 |
| Eloot, S | 4 |
| Bataille, S | 1 |
| Pelletier, M | 1 |
| Sallée, M | 3 |
| Berland, Y | 1 |
| Duval, A | 1 |
| Gentile, S | 1 |
| Mouelhi, Y | 1 |
| Brunet, P | 4 |
| Black, AP | 1 |
| Anjos, JS | 1 |
| Cardozo, L | 1 |
| Carmo, FL | 1 |
| Dolenga, CJ | 1 |
| Nakao, LS | 1 |
| de Carvalho Ferreira, D | 1 |
| Rosado, A | 1 |
| Carraro Eduardo, JC | 1 |
| Addi, T | 1 |
| El Mecherfi, KE | 1 |
| Kheroua, O | 1 |
| Jourde-Chiche, N | 3 |
| de Macedo, A | 1 |
| Gondouin, B | 3 |
| Dignat-George, F | 3 |
| Dou, L | 3 |
| Chinnappa, S | 1 |
| Tu, YK | 1 |
| Yeh, YC | 1 |
| Vanholder, R | 3 |
| Mooney, A | 1 |
| Lopes, RCSO | 1 |
| Theodoro, JMV | 1 |
| da Silva, BP | 1 |
| Queiroz, VAV | 1 |
| de Castro Moreira, ME | 1 |
| Mantovani, HC | 1 |
| Hermsdorff, HH | 1 |
| Martino, HSD | 1 |
| Bennis, Y | 1 |
| Cluet, Y | 1 |
| Titeca-Beauport, D | 1 |
| El Esper, N | 1 |
| Ureña, P | 1 |
| Bodeau, S | 1 |
| Combe, C | 1 |
| Dussol, B | 2 |
| Fouque, D | 1 |
| Marzouki, S | 1 |
| Masereeuw, R | 1 |
| Schneditz, D | 1 |
| Duval-Sabatier, A | 1 |
| Pletinck, A | 1 |
| Calaf, R | 2 |
| Lacroix, R | 1 |
| Arnaud, L | 1 |
| Fallague, K | 1 |
| Mallet, B | 1 |
| Massy, Z | 1 |
| Liu, H | 1 |
| Narayanan, R | 1 |
| Hoffmann, M | 1 |
| Surapaneni, S | 1 |
| Ichimura, Y | 1 |
| Takamatsu, H | 1 |
| Ideuchi, H | 1 |
| Oda, M | 1 |
| Takeda, K | 1 |
| Saitoh, H | 1 |
| Villain, C | 1 |
| Karu, N | 1 |
| McKercher, C | 1 |
| Nichols, DS | 1 |
| Davies, N | 1 |
| Shellie, RA | 1 |
| Hilder, EF | 1 |
| Jose, MD | 1 |
| Boelaert, J | 1 |
| Lynen, F | 1 |
| Van Landschoot, M | 1 |
| Waterloos, MA | 1 |
| Sandra, P | 1 |
| AMERIO, A | 2 |
| MICELLI, O | 2 |
3 reviews available for indoleacetic acid and Chronic Kidney Diseases
| Article | Year |
|---|---|
Gut microbiota-derived tryptophan metabolism mediates renal fibrosis by aryl hydrocarbon receptor signaling activation.
Topics: Biological Products; Cytochrome P-450 CYP2E1; Gastrointestinal Microbiome; Humans; Indoleacetic Acid | 2021 |
Aryl Hydrocarbon Receptor Activation in Chronic Kidney Disease: Role of Uremic Toxins.
Topics: Animals; Cardiovascular Diseases; Glucuronates; Humans; Indican; Indoleacetic Acids; Indoles; Models | 2017 |
Protein-bound toxins: has the Cinderella of uraemic toxins turned into a princess?
Topics: Animals; Cardiovascular Diseases; Cresols; Humans; Indican; Indoleacetic Acids; Proteins; Renal Insu | 2016 |
2 trials available for indoleacetic acid and Chronic Kidney Diseases
| Article | Year |
|---|---|
Synbiotic meal decreases uremic toxins in hemodialysis individuals: A placebo-controlled trial.
Topics: Aged; Bifidobacterium longum; Biomarkers; Brazil; Cresols; Female; Gastrointestinal Microbiome; Huma | 2019 |
The Effect of Sevelamer on Serum Levels of Gut-Derived Uremic Toxins: Results from In Vitro Experiments and A Multicenter, Double-Blind, Placebo-Controlled, Randomized Clinical Trial.
Topics: Adsorption; Aged; Chelating Agents; Cresols; Double-Blind Method; Female; Gastrointestinal Tract; Hu | 2019 |
23 other studies available for indoleacetic acid and Chronic Kidney Diseases
| Article | Year |
|---|---|
Gut Microbiota and Their Derived Metabolites, a Search for Potential Targets to Limit Accumulation of Protein-Bound Uremic Toxins in Chronic Kidney Disease.
Topics: Butyric Acid; Cohort Studies; Dysbiosis; Feces; Gastrointestinal Microbiome; Humans; Indoleacetic Ac | 2021 |
Indole-3-acetic acid correlates with monocyte-to-high-density lipoprotein (HDL) ratio (MHR) in chronic kidney disease patients.
Topics: Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Female; Humans; Indoleacetic Acids; Lipoprote | 2022 |
Tryptophan Metabolites Regulate Neuropentraxin 1 Expression in Endothelial Cells.
Topics: Animals; C-Reactive Protein; Carbazoles; Cells, Cultured; Disease Models, Animal; Human Umbilical Ve | 2022 |
Serum Levels and Removal by Haemodialysis and Haemodiafiltration of Tryptophan-Derived Uremic Toxins in ESKD Patients.
Topics: Adult; Aged; Aged, 80 and over; Female; Hemodiafiltration; Humans; Indican; Indoleacetic Acids; Kidn | 2020 |
Isolation and Quantification of Uremic Toxin Precursor-Generating Gut Bacteria in Chronic Kidney Disease Patients.
Topics: Amino Acids, Aromatic; Bacteria; Cresols; Feces; Gastrointestinal Microbiome; Humans; Indican; Indol | 2020 |
Difference in Profiles of the Gut-Derived Tryptophan Metabolite Indole Acetic Acid between Transplanted and Non-Transplanted Patients with Chronic Kidney Disease.
Topics: Adult; Aged; Biomarkers; Female; Glomerular Filtration Rate; Graft Survival; Humans; Indoleacetic Ac | 2020 |
Factors of microinflammation in non-diabetic chronic kidney disease: a pilot study.
Topics: Bacterial Translocation; Biomarkers; C-Reactive Protein; Female; Gastrointestinal Microbiome; Humans | 2020 |
pH-Dependent Protein Binding Properties of Uremic Toxins In Vitro.
Topics: Calorimetry; Circular Dichroism; Cresols; Humans; Hydrogen-Ion Concentration; Indican; Indoleacetic | 2021 |
Exploring binding characteristics and the related competition of different protein-bound uremic toxins.
Topics: Binding, Competitive; Case-Control Studies; Chromatography, High Pressure Liquid; Cresols; Hippurate | 2017 |
Indole 3-acetic acid, indoxyl sulfate and paracresyl-sulfate do not influence anemia parameters in hemodialysis patients.
Topics: Aged; Aged, 80 and over; Anemia; Biomarkers; Cross-Sectional Studies; Female; Humans; Indican; Indol | 2017 |
Does Low-Protein Diet Influence the Uremic Toxin Serum Levels From the Gut Microbiota in Nondialysis Chronic Kidney Disease Patients?
Topics: Adult; Aged; Cresols; Diet, Protein-Restricted; Feces; Female; Gastrointestinal Microbiome; Humans; | 2018 |
Mechanisms of tissue factor induction by the uremic toxin indole-3 acetic acid through aryl hydrocarbon receptor/nuclear factor-kappa B signaling pathway in human endothelial cells.
Topics: Adult; Aged; Aged, 80 and over; Basic Helix-Loop-Helix Transcription Factors; Cells, Cultured; Femal | 2019 |
Association between Protein-Bound Uremic Toxins and Asymptomatic Cardiac Dysfunction in Patients with Chronic Kidney Disease.
Topics: Adult; Arterial Pressure; Cardiac Output; Cresols; Exercise; Glucuronides; Heart Diseases; Heart Rat | 2018 |
Selective Transport of Protein-Bound Uremic Toxins in Erythrocytes.
Topics: Biological Transport; Cresols; Erythrocytes; Hippurates; Humans; Indican; Indoleacetic Acids; Protei | 2019 |
Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway.
Topics: Adult; Aged; Aged, 80 and over; Benzoquinones; Case-Control Studies; Cells, Cultured; Dioxins; Endot | 2013 |
The cardiovascular effect of the uremic solute indole-3 acetic acid.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cyclooxygenase 2; Endothelium, Vascular; Fe | 2015 |
Exploring Protein Binding of Uremic Toxins in Patients with Different Stages of Chronic Kidney Disease and during Hemodialysis.
Topics: Aged; Aged, 80 and over; Cresols; Cross-Sectional Studies; Female; Glucuronides; Hippurates; Humans; | 2015 |
The Uremic Toxin Indoxyl-3-Sulfate Induces CYP1A2 In Primary Human Hepatocytes.
Topics: Adult; Aged; Cells, Cultured; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Female; Hep | 2016 |
Correlations between Plasma Levels of Anionic Uremic Toxins and Clinical Parameters in Hemodialysis Patients.
Topics: Aged; Aged, 80 and over; Biomarkers; Blood Urea Nitrogen; Creatinine; Female; Furans; Glomerular Fil | 2016 |
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study.
Topics: Aged; Aged, 80 and over; Anxiety; Biomarkers; Cognition; Cross-Sectional Studies; Depression; Female | 2016 |
A novel UPLC-MS-MS method for simultaneous determination of seven uremic retention toxins with cardiovascular relevance in chronic kidney disease patients.
Topics: Cardiovascular Diseases; Case-Control Studies; Chromatography, High Pressure Liquid; Cresols; Female | 2013 |
[The urinary excretion of 5-hydroxyindolacetic acid in normal humans and in patients with chronic kidney diseases. I. Determination by a biochemical method].
Topics: Hydroxyindoleacetic Acid; Indoleacetic Acids; Kidney Diseases; Renal Insufficiency, Chronic | 1958 |
[The urinary excretion of 5-hydroxyindolacetic acid in normal humans and in patients with chronic kidney diseases. II. Chromatographic determination].
Topics: Chromatography; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kidney Diseases; Renal Insufficiency, | 1958 |