indole and Uremia
indole has been researched along with Uremia in 5 studies
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Tanaka, H | 1 |
| Sirich, TL | 1 |
| Plummer, NS | 1 |
| Weaver, DS | 1 |
| Meyer, TW | 1 |
| Palm, F | 1 |
| Nangaku, M | 2 |
| Fasching, A | 1 |
| Tanaka, T | 2 |
| Nordquist, L | 1 |
| Hansell, P | 1 |
| Kawakami, T | 1 |
| Nishijima, F | 1 |
| Fujita, T | 2 |
| Chiang, CK | 1 |
| Inagi, R | 1 |
| Niwa, T | 1 |
| Ise, M | 1 |
| Miyazaki, T | 1 |
| Hohenegger, M | 1 |
| Vermes, M | 1 |
| Esposito, R | 1 |
| Giordano, C | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Probiotics on Modulating the Bacterial Translocation and Improving Micro-inflammation in Hemodialysis Patients[NCT02929225] | Early Phase 1 | 50 participants (Actual) | Interventional | 2016-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Other Studies
5 other studies available for indole and Uremia
| Article | Year |
|---|---|
An Enlarged Profile of Uremic Solutes.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Female; Humans; Indoles; Male; Metabolome; Middle Age | 2015 |
Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress.
Topics: Acetophenones; Animals; Carbon; Cell Hypoxia; Disease Models, Animal; Disease Progression; Enzyme In | 2010 |
Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner.
Topics: Animals; Blotting, Western; Cobalt; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Gene Expressi | 2011 |
Progression of glomerular sclerosis in experimental uremic rats by administration of indole, a precursor of indoxyl sulfate.
Topics: Animals; Glomerulosclerosis, Focal Segmental; Indican; Indoles; Kidney Glomerulus; Male; Nephrectomy | 1994 |
Effect of some uremic toxins on oxygen consumption of rats in vivo and in vitro.
Topics: Acetoin; Animals; Cresols; Drug Combinations; Indoles; Male; Methylguanidine; Oxygen Consumption; Pu | 1988 |