Page last updated: 2024-10-18

indole and Innate Inflammatory Response

indole has been researched along with Innate Inflammatory Response in 12 studies

Research Excerpts

ExcerptRelevanceReference
"Indeed, depression is associated with increased expression of interferon-γ, interleukin-1β, and tumor necrosis factor α (TNF-α)."6.58Tryptophan catabolites along the indoleamine 2,3-dioxygenase pathway as a biological link between depression and cancer. ( Barreto, FS; Chaves Filho, AJM; de Araújo, MCCR; de Lucena, DF; de Moraes, MEA; de Moraes, MO; Macedo, DS; Maes, M, 2018)
"Acute lung injury was efficiently treated by inhibiting the cascade of inflammation, and reducing the inflammatory response in the lung."5.62Design, synthesis and structure-activity relationship studies of 4-indole-2-arylaminopyrimidine derivatives as anti-inflammatory agents for acute lung injury. ( Chen, T; Wei, Y; Zhang, X; Zhao, H; Zhu, G, 2021)
"Indole is a microbiota metabolite that exerts anti-inflammatory responses."5.56Indole Alleviates Diet-Induced Hepatic Steatosis and Inflammation in a Manner Involving Myeloid Cell 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3. ( Alpini, G; Athrey, G; Botchlett, R; Chen, L; Francis, H; Glaser, S; Hu, J; Li, H; Li, Q; Ma, L; Matthews, D; Meng, F; Threadgill, DW; Wu, C; Xiao, X; Zeng, T; Zheng, J; Zhou, J, 2020)
"Indeed, depression is associated with increased expression of interferon-γ, interleukin-1β, and tumor necrosis factor α (TNF-α)."2.58Tryptophan catabolites along the indoleamine 2,3-dioxygenase pathway as a biological link between depression and cancer. ( Barreto, FS; Chaves Filho, AJM; de Araújo, MCCR; de Lucena, DF; de Moraes, MEA; de Moraes, MO; Macedo, DS; Maes, M, 2018)
"Acute lung injury was efficiently treated by inhibiting the cascade of inflammation, and reducing the inflammatory response in the lung."1.62Design, synthesis and structure-activity relationship studies of 4-indole-2-arylaminopyrimidine derivatives as anti-inflammatory agents for acute lung injury. ( Chen, T; Wei, Y; Zhang, X; Zhao, H; Zhu, G, 2021)
"Indole is a microbiota metabolite that exerts anti-inflammatory responses."1.56Indole Alleviates Diet-Induced Hepatic Steatosis and Inflammation in a Manner Involving Myeloid Cell 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3. ( Alpini, G; Athrey, G; Botchlett, R; Chen, L; Francis, H; Glaser, S; Hu, J; Li, H; Li, Q; Ma, L; Matthews, D; Meng, F; Threadgill, DW; Wu, C; Xiao, X; Zeng, T; Zheng, J; Zhou, J, 2020)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (58.33)24.3611
2020's5 (41.67)2.80

Authors

AuthorsStudies
Salem, AZ1
Medhat, D1
Fathy, SA1
Mohamed, MR1
El-Khayat, Z1
El-Daly, SM1
Delgado, I1
Cussotto, S1
Anesi, A1
Dexpert, S1
Aubert, A1
Aouizerate, B1
Beau, C1
Forestier, D1
Ledaguenel, P1
Magne, E1
Mattivi, F1
Capuron, L1
Ma, L1
Li, H1
Hu, J1
Zheng, J1
Zhou, J1
Botchlett, R1
Matthews, D1
Zeng, T1
Chen, L1
Xiao, X1
Athrey, G1
Threadgill, DW1
Li, Q2
Glaser, S1
Francis, H1
Meng, F1
Alpini, G1
Wu, C1
Razak, S1
Afsar, T1
Bibi, N1
Abulmeaty, M1
Qamar, W1
Almajwal, A1
Inam, A1
Al Disi, D1
Shabbir, M1
Bhat, MA1
Chen, T1
Wei, Y1
Zhu, G1
Zhao, H1
Zhang, X1
Barreto, FS1
Chaves Filho, AJM1
de Araújo, MCCR1
de Moraes, MO1
de Moraes, MEA1
Maes, M1
de Lucena, DF1
Macedo, DS1
Srour, AM1
Panda, SS1
M Salman, AM1
El-Manawaty, MA1
George, RF1
Shalaby, EM1
Fitch, AN1
Fawzy, NG1
Girgis, AS1
Dai, W1
Ge, X1
Xu, T1
Lu, C1
Zhou, W1
Sun, D1
Gong, Y1
Dai, Y1
Song, Z1
Zhou, Y1
Zhang, W1
Zhan, L1
Yu, Y1
Chen, Y1
Jia, W1
Liu, Z1
Qian, J1
Zhang, Y1
Li, C1
Liang, G1
Whitfield-Cargile, CM1
Cohen, ND1
Chapkin, RS1
Weeks, BR1
Davidson, LA1
Goldsby, JS1
Hunt, CL1
Steinmeyer, SH1
Menon, R1
Suchodolski, JS1
Jayaraman, A2
Alaniz, RC2
Rothhammer, V1
Mascanfroni, ID1
Bunse, L1
Takenaka, MC1
Kenison, JE1
Mayo, L1
Chao, CC1
Patel, B1
Yan, R1
Blain, M1
Alvarez, JI1
Kébir, H1
Anandasabapathy, N1
Izquierdo, G1
Jung, S1
Obholzer, N1
Pochet, N1
Clish, CB1
Prinz, M1
Prat, A1
Antel, J1
Quintana, FJ1
Bansal, T1
Wood, TK1

Reviews

1 review available for indole and Innate Inflammatory Response

ArticleYear
Tryptophan catabolites along the indoleamine 2,3-dioxygenase pathway as a biological link between depression and cancer.
    Behavioural pharmacology, 2018, Volume: 29, Issue:2 and 3-Sp

    Topics: Animals; Depression; Depressive Disorder; Humans; Immunity; Indoleamine-Pyrrole 2,3,-Dioxygenase; In

2018

Other Studies

11 other studies available for indole and Innate Inflammatory Response

ArticleYear
Indole glucosinolates exhibit anti-inflammatory effects on Ehrlich ascites carcinoma cells through modulation of inflammatory markers and miRNAs.
    Molecular biology reports, 2021, Volume: 48, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers, Tumor; Body Weight; Carcinoma, Ehrlich Tumor; Cell Pr

2021
Association between the indole pathway of tryptophan metabolism and subclinical depressive symptoms in obesity: a preliminary study.
    International journal of obesity (2005), 2022, Volume: 46, Issue:4

    Topics: C-Reactive Protein; Depression; Humans; Indoles; Inflammation; Kynurenine; Obesity; Tryptophan

2022
Indole Alleviates Diet-Induced Hepatic Steatosis and Inflammation in a Manner Involving Myeloid Cell 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3.
    Hepatology (Baltimore, Md.), 2020, Volume: 72, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Animals; Cells, Cultured; Diet, High-Fat; Female; Hepatocytes; Human

2020
Molecular docking, pharmacokinetic studies, and in vivo pharmacological study of indole derivative 2-(5-methoxy-2-methyl-1H-indole-3-yl)-N'-[(E)-(3-nitrophenyl) methylidene] acetohydrazide as a promising chemoprotective agent against cisplatin induced org
    Scientific reports, 2021, 03-18, Volume: 11, Issue:1

    Topics: Animals; Antineoplastic Agents; Antioxidants; Cisplatin; Glutathione Peroxidase; Indoles; Inflammati

2021
Design, synthesis and structure-activity relationship studies of 4-indole-2-arylaminopyrimidine derivatives as anti-inflammatory agents for acute lung injury.
    European journal of medicinal chemistry, 2021, Dec-05, Volume: 225

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cytokines; Dose-Resp

2021
Synthesis & molecular modeling studies of bronchodilatory active indole-pyridine conjugates.
    Future medicinal chemistry, 2018, 08-01, Volume: 10, Issue:15

    Topics: Animals; Biological Assay; Bronchodilator Agents; Dose-Response Relationship, Drug; Guinea Pigs; Ind

2018
Two indole-2-carboxamide derivatives attenuate lipopolysaccharide-induced acute lung injury by inhibiting inflammatory response.
    Canadian journal of physiology and pharmacology, 2018, Volume: 96, Issue:12

    Topics: Acute Lung Injury; Amides; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Gene Expression; Indole

2018
Base promoted synthesis of novel indole-dithiocarbamate compounds as potential anti-inflammatory therapeutic agents for treatment of acute lung injury.
    European journal of medicinal chemistry, 2019, Jun-01, Volume: 171

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Dru

2019
The microbiota-derived metabolite indole decreases mucosal inflammation and injury in a murine model of NSAID enteropathy.
    Gut microbes, 2016, 05-03, Volume: 7, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Biota; Disease

2016
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.
    Nature medicine, 2016, Volume: 22, Issue:6

    Topics: Animals; Astrocytes; Case-Control Studies; Cell Proliferation; Central Nervous System; Chemokine CCL

2016
The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jan-05, Volume: 107, Issue:1

    Topics: Bacteria; Cell Line; Chemokines; Cytokines; Epithelial Cells; Humans; Indoles; Inflammation; Microar

2010