indole has been researched along with Hepatitis C in 1 studies
Hepatitis C: INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to identify the inhibitors of hepatitis C virus (HCV) replication with a novel scaffold via a mechanistically unbiased approach, we screened our in-house library composed of ∼6000 compounds with various chemical structures by using the renilla luciferase-linked genotype 2a reporter virus, and we identified a series of compounds containing an indole moiety that were active against HCV replication." | 3.80 | Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors. ( Choi, M; Jin, G; Kim, GW; Lee, C; Lee, K; Lee, S; Oh, JW; Son, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, G | 1 |
| Lee, S | 1 |
| Choi, M | 1 |
| Son, S | 1 |
| Kim, GW | 1 |
| Oh, JW | 1 |
| Lee, C | 1 |
| Lee, K | 1 |
1 other study available for indole and Hepatitis C
| Article | Year |
|---|---|
Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors.
Topics: Antiviral Agents; Cell Line; Drug Discovery; Genome, Viral; Hepacivirus; Hepatitis C; Humans; Indole | 2014 |