indole has been researched along with Colorectal Neoplasms in 3 studies
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tyrindoleninone was less potent but significantly decreased the viability of HT29 cells at IC50 = 390 µM and induced apoptosis at 195 µM by increasing caspase 3/7 activity in these cells." | 5.39 | Purified brominated indole derivatives from Dicathais orbita induce apoptosis and cell cycle arrest in colorectal cancer cell lines. ( Abbott, CA; Benkendorff, K; Esmaeelian, B; Johnston, MR, 2013) |
| "Tyrindoleninone was less potent but significantly decreased the viability of HT29 cells at IC50 = 390 µM and induced apoptosis at 195 µM by increasing caspase 3/7 activity in these cells." | 1.39 | Purified brominated indole derivatives from Dicathais orbita induce apoptosis and cell cycle arrest in colorectal cancer cell lines. ( Abbott, CA; Benkendorff, K; Esmaeelian, B; Johnston, MR, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y | 1 |
| Pei, Z | 1 |
| Pan, T | 1 |
| Wang, H | 1 |
| Chen, W | 1 |
| Lu, W | 1 |
| Esmaeelian, B | 1 |
| Benkendorff, K | 1 |
| Johnston, MR | 1 |
| Abbott, CA | 1 |
| Toden, S | 1 |
| Scherer, BL | 1 |
| Clarke, JM | 1 |
2 reviews available for indole and Colorectal Neoplasms
| Article | Year |
|---|---|
Indole metabolites and colorectal cancer: Gut microbial tryptophan metabolism, host gut microbiome biomarkers, and potential intervention mechanisms.
Topics: Bacteria; Biomarkers; Colorectal Neoplasms; Gastrointestinal Microbiome; Humans; Indoles; Tryptophan | 2023 |
Can indole-based extracts prevent colorectal cancer via early apoptotic pathways?
Topics: Animals; Apoptosis; Colorectal Neoplasms; Female; Indoles; Mice; Mice, Inbred C57BL | 2010 |
1 other study available for indole and Colorectal Neoplasms
| Article | Year |
|---|---|
Purified brominated indole derivatives from Dicathais orbita induce apoptosis and cell cycle arrest in colorectal cancer cell lines.
Topics: Animals; Apoptosis; Biological Factors; Caco-2 Cells; Caspase 3; Caspase 7; Cell Cycle Checkpoints; | 2013 |