Page last updated: 2024-10-18

indole and Astrocytoma, Grade IV

indole has been researched along with Astrocytoma, Grade IV in 3 studies

Research Excerpts

ExcerptRelevanceReference
" To explore the induction of methuosis as a potential therapeutic strategy for killing cancer cells, we have developed small molecules (indole-based chalcones) that trigger this form of cell death in glioblastoma and other cancer cell lines."7.85Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones. ( Maltese, WA; Mbah, NE; Overmeyer, JH, 2017)
" To explore the induction of methuosis as a potential therapeutic strategy for killing cancer cells, we have developed small molecules (indole-based chalcones) that trigger this form of cell death in glioblastoma and other cancer cell lines."3.85Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones. ( Maltese, WA; Mbah, NE; Overmeyer, JH, 2017)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Sherer, C1
Tolaymat, I1
Rowther, F1
Warr, T1
Snape, TJ1
Nguyen, P1
Doan, P1
Rimpilainen, T1
Konda Mani, S1
Murugesan, A1
Yli-Harja, O1
Candeias, NR1
Kandhavelu, M1
Mbah, NE1
Overmeyer, JH1
Maltese, WA1

Other Studies

3 other studies available for indole and Astrocytoma, Grade IV

ArticleYear
Preliminary SAR on indole-3-carbinol and related fragments reveals a novel anticancer lead compound against resistant glioblastoma cells.
    Bioorganic & medicinal chemistry letters, 2017, 04-01, Volume: 27, Issue:7

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening

2017
Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment.
    Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationshi

2021
Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones.
    Cell biology and toxicology, 2017, Volume: 33, Issue:3

    Topics: Amyloid beta-Protein Precursor; Apoptosis; Autophagosomes; Autophagy; Cell Line, Tumor; Cell Surviva

2017