indole has been researched along with Anesthesia in 2 studies
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since tetrahydro-β-carbolines and β-carbolines target receptors, ion channels and neuronal membranes which are common to anesthetic agents, we propose a hypothesis that they may pharmacodynamically interact at GABAA receptors, NMDA receptors, voltage-gated Na(+) channels and membrane lipid bilayers to attenuate anesthetics-induced positive allosteric GABAA receptor modulation, NMDA receptor antagonism, ion channel blockade and neuronal membrane modification, thereby affecting anesthetic efficacy." | 1.43 | Anesthetic effects changeable in habitual drinkers: Mechanistic drug interactions with neuro-active indoleamine-aldehyde condensation products associated with alcoholic beverage consumption. ( Tsuchiya, H, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsuchiya, H | 1 |
| CHEVREMONT, M | 1 |
| CHEVREMONT-COMHAIRE, S | 1 |
2 other studies available for indole and Anesthesia
| Article | Year |
|---|---|
Anesthetic effects changeable in habitual drinkers: Mechanistic drug interactions with neuro-active indoleamine-aldehyde condensation products associated with alcoholic beverage consumption.
Topics: Alcohol Drinking; Alcoholism; Aldehydes; Amines; Anesthesia; Anesthetics; Animals; Carbolines; Drug | 2016 |
[Cellular action of trihydroxy-N-methylindole, particularly on mitochondria].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Indoles; Mitochondria; Pain; Pain Management; Proca | 1953 |