indole-3-carbinol has been researched along with Pregnancy in 12 studies
indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We now show that during pregnancy, administration of a diet rich in the aryl hydrocarbon receptor (AHR) ligand indole-3-carbinole (I3C), or of breast milk, activates AHR and prevents NEC in newborn mice by reducing Toll-like receptor 4 (TLR4) signaling in the newborn gut." | 4.02 | Maternal aryl hydrocarbon receptor activation protects newborns against necrotizing enterocolitis. ( Fulton, WB; Hackam, DJ; Jia, H; Kovler, ML; Lu, P; Prindle, T; Salazar, AG; Sampah, M; Sodhi, CP; Wang, S; Wipf, P; Yamaguchi, Y; Zhou, Q, 2021) |
| "Bisphenol A (BPA) is a chemical that has been investigated for it potential to cause prostate diseases." | 1.40 | Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats. ( Anselmo-Franci, JA; Barbisan, LF; Brandt, JZ; Fávaro, WJ; Felisbino, SL; Grassi, TF; Scarano, WR; Silveira, LT, 2014) |
| " The bioavailability of DBP to fetal target tissue was demonstrated by assessing DNA covalent adduction with a (33)P-post-labeling assay." | 1.33 | Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the polycyclic aromatic hydrocarbon dibenzo[a,l]pyrene. ( Albershardt, DJ; Bailey, GS; Baird, WM; Fischer, KA; Krueger, SK; Löhr, CV; Louderback, MA; Mahadevan, B; Pereira, CB; Williams, DE; Yu, Z, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Guzmán-Navarro, G | 1 |
| León, MB | 1 |
| Martín-Estal, I | 1 |
| Durán, RC | 1 |
| Villarreal-Alvarado, L | 1 |
| Vaquera-Vázquez, A | 1 |
| Cuevas-Cerda, T | 1 |
| Garza-García, K | 1 |
| Cuervo-Pérez, LE | 1 |
| Barbosa-Quintana, Á | 1 |
| Pérez-Saucedo, JE | 1 |
| Lara-Díaz, VJ | 1 |
| Castorena-Torres, F | 1 |
| Lu, P | 1 |
| Yamaguchi, Y | 1 |
| Fulton, WB | 1 |
| Wang, S | 1 |
| Zhou, Q | 1 |
| Jia, H | 1 |
| Kovler, ML | 1 |
| Salazar, AG | 1 |
| Sampah, M | 1 |
| Prindle, T | 1 |
| Wipf, P | 1 |
| Sodhi, CP | 1 |
| Hackam, DJ | 1 |
| Benninghoff, AD | 1 |
| Williams, DE | 4 |
| Shorey, LE | 1 |
| Madeen, EP | 1 |
| Atwell, LL | 1 |
| Ho, E | 1 |
| Löhr, CV | 2 |
| Pereira, CB | 2 |
| Dashwood, RH | 1 |
| Brandt, JZ | 1 |
| Silveira, LT | 1 |
| Grassi, TF | 2 |
| Anselmo-Franci, JA | 1 |
| Fávaro, WJ | 1 |
| Felisbino, SL | 1 |
| Barbisan, LF | 2 |
| Scarano, WR | 1 |
| da Silva, GN | 1 |
| Bidinotto, LT | 1 |
| Rossi, BF | 1 |
| Quinalha, MM | 1 |
| Kass, L | 1 |
| Muñoz-de-Toro, M | 1 |
| Chang, AS | 1 |
| Grant, R | 1 |
| Tomita, H | 1 |
| Kim, HS | 1 |
| Smithies, O | 1 |
| Kakoki, M | 1 |
| Bailey, MM | 1 |
| Sawyer, RD | 1 |
| Behling, JE | 1 |
| Boohaker, JG | 1 |
| Hicks, JG | 1 |
| O'donnell, MA | 1 |
| Stringer, KR | 1 |
| Rasco, JF | 1 |
| Hood, RD | 1 |
| Yu, Z | 1 |
| Mahadevan, B | 1 |
| Fischer, KA | 1 |
| Louderback, MA | 1 |
| Krueger, SK | 1 |
| Albershardt, DJ | 1 |
| Baird, WM | 1 |
| Bailey, GS | 1 |
| Yan, YE | 1 |
| Wang, H | 1 |
| Wang, T | 1 |
| Zeng, HG | 1 |
| Wilker, C | 1 |
| Johnson, L | 1 |
| Safe, S | 1 |
| Larsen-Su, SA | 1 |
12 other studies available for indole-3-carbinol and Pregnancy
| Article | Year |
|---|---|
Prenatal indole-3-carbinol administration activates aryl hydrocarbon receptor-responsive genes and attenuates lung injury in a bronchopulmonary dysplasia model.
Topics: Animals; Animals, Newborn; Bronchopulmonary Dysplasia; Cytokines; Disease Models, Animal; Female; Fi | 2021 |
Maternal aryl hydrocarbon receptor activation protects newborns against necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Basic Helix-Loop-Helix Transcription Factors; Cytochrome P-450 CYP1A1; Di | 2021 |
The role of estrogen receptor β in transplacental cancer prevention by indole-3-carbinol.
Topics: Animals; Anticarcinogenic Agents; Benzopyrenes; Carcinogens; Chemoprevention; Drug Evaluation, Precl | 2013 |
Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: maternal diets rich in indole-3-carbinol versus sulforaphane.
Topics: Animals; Anticarcinogenic Agents; Benzopyrenes; Carcinogens; Diet; Female; Indoles; Isothiocyanates; | 2013 |
Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats.
Topics: Animals; Apoptosis; Benzhydryl Compounds; Cell Proliferation; Endocrine Disruptors; Epithelial Cells | 2014 |
Global gene expression and morphological alterations in the mammary gland after gestational exposure to bisphenol A, genistein and indole-3-carbinol in female Sprague-Dawley offspring.
Topics: Animals; Anticarcinogenic Agents; Benzhydryl Compounds; Estrogens, Non-Steroidal; Female; Gene Expre | 2016 |
Prolactin alters blood pressure by modulating the activity of endothelial nitric oxide synthase.
Topics: Animals; Blood Pressure; Female; Gene Expression; Humans; Hypertension; Indoles; Male; Mice, Knockou | 2016 |
Prior exposure to indole-3-carbinol decreases the incidence of specific cyclophosphamide-induced developmental defects in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cyclophosphamide; Female; Fetal Development; Fetus; Indoles; M | 2005 |
Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by the polycyclic aromatic hydrocarbon dibenzo[a,l]pyrene.
Topics: Animals; Anticarcinogenic Agents; Benzopyrenes; Biological Availability; Diet; DNA Adducts; Female; | 2006 |
Indole-3-carbinol alters placental cytochrome P450 1A1 and P-glycoprotein levels in rats: a potential role in intensifying fetal intrauterine growth-retardation produced by tobacco smoke.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Birth Weight | 2006 |
Effects of developmental exposure to indole-3-carbinol or 2,3,7,8-tetrachlorodibenzo-p-dioxin on reproductive potential of male rat offspring.
Topics: Animals; Estrogen Antagonists; Female; Genitalia, Male; Indoles; Male; Polychlorinated Dibenzodioxin | 1996 |
Transplacental exposure to indole-3-carbinol induces sex-specific expression of CYP1A1 and CYP1B1 in the liver of Fischer 344 neonatal rats.
Topics: Animals; Animals, Newborn; Antioxidants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cyt | 2001 |