indole-3-carbinol has been researched along with Pancreatic Neoplasms in 5 studies
indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Female pancreatic cancer cells were more resistant to gemcitabine alone." | 1.36 | Gender differences in gemcitabine (Gemzar) efficacy in cancer cells: effect of indole-3-carbinol. ( Davis, C; Haefele, A; Hammons, G; Lyn-Cook, BD; Mohammed, SI; Wang, H; Word, B, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krajka-Kuźniak, V | 1 |
| Cykowiak, M | 1 |
| Szaefer, H | 1 |
| Kleszcz, R | 1 |
| Baer-Dubowska, W | 1 |
| Paik, WH | 1 |
| Kim, HR | 1 |
| Park, JK | 1 |
| Song, BJ | 1 |
| Lee, SH | 1 |
| Hwang, JH | 1 |
| Lyn-Cook, BD | 2 |
| Mohammed, SI | 1 |
| Davis, C | 1 |
| Word, B | 1 |
| Haefele, A | 1 |
| Wang, H | 2 |
| Hammons, G | 1 |
| Word, BR | 1 |
| Morse, MA | 1 |
| Wang, CX | 1 |
| Amin, SG | 1 |
| Hecht, SS | 1 |
| Chung, FL | 1 |
5 other studies available for indole-3-carbinol and Pancreatic Neoplasms
| Article | Year |
|---|---|
Combination of xanthohumol and phenethyl isothiocyanate inhibits NF-κB and activates Nrf2 in pancreatic cancer cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Ce | 2020 |
Chemosensitivity induced by down-regulation of microRNA-21 in gemcitabine-resistant pancreatic cancer cells by indole-3-carbinol.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Blotting, | 2013 |
Gender differences in gemcitabine (Gemzar) efficacy in cancer cells: effect of indole-3-carbinol.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Deoxycytidine; DNA Modification Me | 2010 |
Enhanced efficacy of gemcitabine by indole-3-carbinol in pancreatic cell lines: the role of human equilibrative nucleoside transporter 1.
Topics: Cell Death; Cell Line, Tumor; Deoxycytidine; Drug Synergism; Equilibrative Nucleoside Transporter 1; | 2011 |
Effects of dietary sinigrin or indole-3-carbinol on O6-methylguanine-DNA-transmethylase activity and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA methylation and tumorigenicity in F344 rats.
Topics: Animals; Carcinogens; Diet; DNA; Glucosinolates; Indoles; Liver Neoplasms; Lung Neoplasms; Male; Met | 1988 |