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indole-3-carbinol and Ovarian Neoplasms

indole-3-carbinol has been researched along with Ovarian Neoplasms in 2 studies

indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.

Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

Research Excerpts

ExcerptRelevanceReference
"Bortezomib is a proteasome inhibitor with minimal clinical activity as a monotherapy in solid tumours, but its combination with other targeted therapies is being actively investigated as a way to increase its anticarcinogenic properties."1.38Indole-3-carbinol synergistically sensitises ovarian cancer cells to bortezomib treatment. ( Agadjanian, H; Guo, X; Karlan, BY; Kwon, S; Miller, C; Nassanian, H; Orsulic, S; Taylor-Harding, B; Walsh, CS, 2012)
"SK-OV-3 ovarian cancer cells were treated with various doses of I3C, RE or I3C+RE."1.35Synergistic action of dietary phyto-antioxidants on survival and proliferation of ovarian cancer cells. ( Abd Elmageed, ZY; Azam, GA; Braley, P; Fathi, IM; Gaur, RL; Nguyen, L; Ouhtit, A; Raj, MH; Rao, PN; Zhou, J, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Raj, MH1
Abd Elmageed, ZY1
Zhou, J1
Gaur, RL1
Nguyen, L1
Azam, GA1
Braley, P1
Rao, PN1
Fathi, IM1
Ouhtit, A1
Taylor-Harding, B1
Agadjanian, H1
Nassanian, H1
Kwon, S1
Guo, X1
Miller, C1
Karlan, BY1
Orsulic, S1
Walsh, CS1

Other Studies

2 other studies available for indole-3-carbinol and Ovarian Neoplasms

ArticleYear
Synergistic action of dietary phyto-antioxidants on survival and proliferation of ovarian cancer cells.
    Gynecologic oncology, 2008, Volume: 110, Issue:3

    Topics: Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis Reg

2008
Indole-3-carbinol synergistically sensitises ovarian cancer cells to bortezomib treatment.
    British journal of cancer, 2012, Jan-17, Volume: 106, Issue:2

    Topics: Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Cycle; Cell Line, Tumor; Drug Synerg

2012