indole-3-carbinol and Local Neoplasm Recurrence studies

indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.

Research Excerpts

Excerpt	Relevance	Reference
"We report the results of a clinical study using Indole-3-Carbinol (I3C) for the treatment of recurrent respiratory papillomatosis (RRP)."	9.11	Indole-3-carbinol for recurrent respiratory papillomatosis: long-term results. ( Bryson, PC; Rosen, CA, 2004)
"We report the preliminary results of a phase I trial using indole-3-carbinol for the treatment of recurrent respiratory papillomatosis."	9.08	Preliminary results of the use of indole-3-carbinol for recurrent respiratory papillomatosis. ( Bradlow, HL; Hengesteg, AP; Rosen, CA; Thompson, JW; Woodson, GE, 1998)
"We report the results of a clinical study using Indole-3-Carbinol (I3C) for the treatment of recurrent respiratory papillomatosis (RRP)."	5.11	Indole-3-carbinol for recurrent respiratory papillomatosis: long-term results. ( Bryson, PC; Rosen, CA, 2004)
"We report the preliminary results of a phase I trial using indole-3-carbinol for the treatment of recurrent respiratory papillomatosis."	5.08	Preliminary results of the use of indole-3-carbinol for recurrent respiratory papillomatosis. ( Bradlow, HL; Hengesteg, AP; Rosen, CA; Thompson, JW; Woodson, GE, 1998)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (16.67)	18.2507
2000's	4 (66.67)	29.6817
2010's	1 (16.67)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Lawrie, TA	1
Nordin, A	1
Chakrabarti, M	1
Bryant, A	1
Kaushik, S	1
Pepas, L	1
Rosen, CA	2
Bryson, PC	1
Huber, K	1
Sadick, H	1
Götte, K	1
Lee, JH	1
Smith, RJ	1
Tasca, RA	1
McCormick, M	1
Clarke, RW	1
Woodson, GE	1
Thompson, JW	1
Hengesteg, AP	1
Bradlow, HL	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
A Single-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of 3,3'-Diindolylmethane (BR-DIM) in Patients With Systemic Lupus Erythematosus (SLE)[NCT02483624]			Phase 1	6 participants (Actual)	Interventional	2016-01-31	Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Medical and surgical interventions for the treatment of usual-type vulval intraepithelial neoplasia. The Cochrane database of systematic reviews, 2016, Jan-05, Issue:1 Topics: Adult; Aminoquinolines; Antineoplastic Agents; Carcinoma in Situ; Cidofovir; Cytosine; Disease Progr	2016
[Current therapeutic options for recurrent respiratory papillomatosis]. HNO, 2005, Volume: 53, Issue:11 Topics: Adult; Chemotherapy, Adjuvant; Child; Cidofovir; Cytosine; Drug Combinations; Follow-Up Studies; Hum	2005
Recurrent respiratory papillomatosis: pathogenesis to treatment. Current opinion in otolaryngology & head and neck surgery, 2005, Volume: 13, Issue:6 Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Cidofovir; Cytosine; Human papillomavirus 11; Human p	2005

Article	Year
Indole-3-carbinol for recurrent respiratory papillomatosis: long-term results. Journal of voice : official journal of the Voice Foundation, 2004, Volume: 18, Issue:2 Topics: Adolescent; Adult; Aged; Anticarcinogenic Agents; Child; Child, Preschool; Female; Follow-Up Studies	2004
Preliminary results of the use of indole-3-carbinol for recurrent respiratory papillomatosis. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1998, Volume: 118, Issue:6 Topics: Adult; Child; Child, Preschool; Estrogen Antagonists; Female; Humans; Indoles; Male; Middle Aged; Ne	1998

indole-3-carbinol and Local Neoplasm Recurrence

Research Excerpts

Research

Studies (6)

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Clinical Trials (1)

Trial Overview

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