indole-3-carbinol has been researched along with Innate Inflammatory Response in 15 studies
indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The objective of our research was to evaluate the protective properties of indole-3-carbinol (I3C) and its effect on redox status parameters, inflammation, and apoptosis intensity in cerebral ischemia/reperfusion injury (CIRI) in rats." | 8.31 | Indole-3-carbinol mitigates oxidative stress and inhibits inflammation in rat cerebral ischemia/reperfusion model. ( Chichai, AS; Kryl'skii, ED; Oleinik, SA; Popova, TN; Razuvaev, GA, 2023) |
| "This study aimed the development of nanocapsules (NCs) for oral indole-3-carbinol (I3C) administration and evaluation of antinociceptive potential of this compound in its two forms, free and nanoencapsulated, using acute pain models." | 7.88 | Nanocapsules improve indole-3-carbinol photostability and prolong its antinociceptive action in acute pain animal models. ( Barbieri, AV; Cruz, L; Farago, PV; Ferreira, LM; Gehrcke, M; Giuliani, LM; Nadal, JM; Nogueira, CW; Prado, VC; Sari, MHM, 2018) |
| " However, patient receiving DOX-therapy, myelosuppression and genotoxicity which may lead to secondary malignancy and dose dependent cardiotoxicity is an imperative adverse effect." | 5.48 | Prevention of doxorubicin (DOX)-induced genotoxicity and cardiotoxicity: Effect of plant derived small molecule indole-3-carbinol (I3C) on oxidative stress and inflammation. ( Basu, A; Bhattacharya, S; Hajra, S; Patra, AR, 2018) |
| "Chronic inflammation is an important risk factor for lung cancer." | 5.42 | Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators. ( Kassie, F; Luo, X; Molla, K; O Sullivan, G; Qian, X; Song, JM; Teferi, F; Upadhyaya, P, 2015) |
| " The objective of our research was to evaluate the protective properties of indole-3-carbinol (I3C) and its effect on redox status parameters, inflammation, and apoptosis intensity in cerebral ischemia/reperfusion injury (CIRI) in rats." | 4.31 | Indole-3-carbinol mitigates oxidative stress and inhibits inflammation in rat cerebral ischemia/reperfusion model. ( Chichai, AS; Kryl'skii, ED; Oleinik, SA; Popova, TN; Razuvaev, GA, 2023) |
| "This study aimed the development of nanocapsules (NCs) for oral indole-3-carbinol (I3C) administration and evaluation of antinociceptive potential of this compound in its two forms, free and nanoencapsulated, using acute pain models." | 3.88 | Nanocapsules improve indole-3-carbinol photostability and prolong its antinociceptive action in acute pain animal models. ( Barbieri, AV; Cruz, L; Farago, PV; Ferreira, LM; Gehrcke, M; Giuliani, LM; Nadal, JM; Nogueira, CW; Prado, VC; Sari, MHM, 2018) |
| " However, patient receiving DOX-therapy, myelosuppression and genotoxicity which may lead to secondary malignancy and dose dependent cardiotoxicity is an imperative adverse effect." | 1.48 | Prevention of doxorubicin (DOX)-induced genotoxicity and cardiotoxicity: Effect of plant derived small molecule indole-3-carbinol (I3C) on oxidative stress and inflammation. ( Basu, A; Bhattacharya, S; Hajra, S; Patra, AR, 2018) |
| "Chronic pulmonary inflammation has been consistently shown to increase the risk of lung cancer." | 1.42 | RNA-sequencing studies identify genes differentially regulated during inflammation-driven lung tumorigenesis and targeted by chemopreventive agents. ( Dickerson, E; Kassie, F; Khammanivong, A; Qian, X; Song, JM; Teferi, F; Upadhyaya, P, 2015) |
| "Chronic inflammation is an important risk factor for lung cancer." | 1.42 | Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators. ( Kassie, F; Luo, X; Molla, K; O Sullivan, G; Qian, X; Song, JM; Teferi, F; Upadhyaya, P, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (66.67) | 24.3611 |
| 2020's | 5 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Amarakoon, D | 1 |
| Lee, WJ | 1 |
| Tamia, G | 1 |
| Lee, SH | 1 |
| Chichai, AS | 1 |
| Popova, TN | 1 |
| Kryl'skii, ED | 1 |
| Oleinik, SA | 1 |
| Razuvaev, GA | 1 |
| Busbee, PB | 1 |
| Menzel, L | 1 |
| Alrafas, HR | 1 |
| Dopkins, N | 1 |
| Becker, W | 1 |
| Miranda, K | 1 |
| Tang, C | 1 |
| Chatterjee, S | 1 |
| Singh, U | 1 |
| Nagarkatti, M | 1 |
| Nagarkatti, PS | 1 |
| H Bakr, ES | 1 |
| El-Yamany, MA | 1 |
| Khan, AS | 1 |
| Langmann, T | 1 |
| Ampofo, E | 2 |
| Lachnitt, N | 1 |
| Rudzitis-Auth, J | 1 |
| Schmitt, BM | 2 |
| Menger, MD | 2 |
| Laschke, MW | 2 |
| Gehrcke, M | 1 |
| Sari, MHM | 1 |
| Ferreira, LM | 1 |
| Barbieri, AV | 1 |
| Giuliani, LM | 1 |
| Prado, VC | 1 |
| Nadal, JM | 1 |
| Farago, PV | 1 |
| Nogueira, CW | 1 |
| Cruz, L | 1 |
| Hajra, S | 1 |
| Patra, AR | 1 |
| Basu, A | 1 |
| Bhattacharya, S | 1 |
| Jiang, J | 1 |
| Kang, TB | 1 |
| Shim, do W | 1 |
| Oh, NH | 1 |
| Kim, TJ | 1 |
| Lee, KH | 1 |
| El-Naga, RN | 1 |
| Ahmed, HI | 1 |
| Abd Al Haleem, EN | 1 |
| Qian, X | 2 |
| Khammanivong, A | 1 |
| Song, JM | 2 |
| Teferi, F | 2 |
| Upadhyaya, P | 2 |
| Dickerson, E | 1 |
| Kassie, F | 2 |
| Molla, K | 1 |
| O Sullivan, G | 1 |
| Luo, X | 1 |
| Choi, Y | 1 |
| Kim, Y | 1 |
| Park, S | 1 |
| Lee, KW | 1 |
| Park, T | 1 |
2 reviews available for indole-3-carbinol and Innate Inflammatory Response
| Article | Year |
|---|---|
Indole-3-Carbinol: Occurrence, Health-Beneficial Properties, and Cellular/Molecular Mechanisms.
Topics: Apoptosis; Cardiovascular Diseases; Humans; Inflammation; Signal Transduction | 2023 |
Targeting the Microcirculation by Indole-3-carbinol and Its Main Derivate 3,3,'-diindolylmethane: Effects on Angiogenesis, Thrombosis and Inflammation.
Topics: Animals; Humans; Indoles; Inflammation; Microcirculation; Neovascularization, Pathologic; Thrombosis | 2018 |
13 other studies available for indole-3-carbinol and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Indole-3-carbinol mitigates oxidative stress and inhibits inflammation in rat cerebral ischemia/reperfusion model.
Topics: Animals; Antioxidants; Apoptosis; Brain Ischemia; Inflammation; Oxidative Stress; Rats; Reperfusion; | 2023 |
Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner.
Topics: Animals; Butyric Acid; Colitis; Colon; Disease Models, Animal; Dysbiosis; Female; Gastrointestinal M | 2020 |
Chemical and Nutraceutical Studies on Infertility of Albino Rats Induced by Cadmium Chloride.
Topics: Albumins; Animals; Brassica; Cadmium Chloride; Dietary Supplements; Fertility; Follicle Stimulating | 2020 |
Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration.
Topics: Animals; Apoptosis; Cell Line; Female; Homeostasis; Indoles; Inflammation; Lipopolysaccharides; Male | 2020 |
Indole-3-carbinol is a potent inhibitor of ischemia-reperfusion-induced inflammation.
Topics: Animals; Biomarkers; Blotting, Western; E-Selectin; Endothelial Cells; Flow Cytometry; Fluorescent A | 2017 |
Nanocapsules improve indole-3-carbinol photostability and prolong its antinociceptive action in acute pain animal models.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Drug S | 2018 |
Prevention of doxorubicin (DOX)-induced genotoxicity and cardiotoxicity: Effect of plant derived small molecule indole-3-carbinol (I3C) on oxidative stress and inflammation.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidant Response Elements; Antioxidants; Apoptosis; Cardio | 2018 |
Indole-3-carbinol inhibits LPS-induced inflammatory response by blocking TRIF-dependent signaling pathway in macrophages.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalve | 2013 |
Effects of indole-3-carbinol on clonidine-induced neurotoxicity in rats: Impact on oxidative stress, inflammation, apoptosis and monoamine levels.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biogenic Monoamines; Brain; Clonidine; D | 2014 |
RNA-sequencing studies identify genes differentially regulated during inflammation-driven lung tumorigenesis and targeted by chemopreventive agents.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Female; Gene Expression Regulation, Neoplastic; Indol | 2015 |
Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators.
Topics: Animals; Anticarcinogenic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Tr | 2015 |
Indole-3-carbinol prevents diet-induced obesity through modulation of multiple genes related to adipogenesis, thermogenesis or inflammation in the visceral adipose tissue of mice.
Topics: 3T3-L1 Cells; Adipogenesis; Adipose Tissue; Animals; Anti-Obesity Agents; Cell Differentiation; Diet | 2012 |