indole-3-carbinol has been researched along with Hormone-Dependent Neoplasms in 6 studies
indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indole-3-carbinol (I3C), autolysis product of glucosinolates present in cruciferous vegetables, has been indicated as a promising agent in preventing the development and progression of breast cancer." | 7.72 | A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines. ( Brandi, G; Cervasi, B; De Marco, C; Filippone, P; Fiorucci, C; Magnani, M; Paiardini, M; Zaffaroni, N, 2003) |
| "The mechanism of action of the anti-estrogen indole-3-carbinol (I3C), present in cruciferous vegetables, is being examined in our laboratory with a view to promote the use of this naturally occurring chemopreventive as an alternative to synthetic anti-estrogens in human breast cancer." | 7.71 | Multiple molecular targets of indole-3-carbinol, a chemopreventive anti-estrogen in breast cancer. ( Ashok, BT; Chen, YG; Garikapaty, VP; Liu, X; Mittelman, A; Roy, K; Seplowitz, R; Tiwari, RK; Tschorn, J, 2002) |
| "Indole-3-carbinol (I3C), autolysis product of glucosinolates present in cruciferous vegetables, has been indicated as a promising agent in preventing the development and progression of breast cancer." | 3.72 | A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines. ( Brandi, G; Cervasi, B; De Marco, C; Filippone, P; Fiorucci, C; Magnani, M; Paiardini, M; Zaffaroni, N, 2003) |
| "The mechanism of action of the anti-estrogen indole-3-carbinol (I3C), present in cruciferous vegetables, is being examined in our laboratory with a view to promote the use of this naturally occurring chemopreventive as an alternative to synthetic anti-estrogens in human breast cancer." | 3.71 | Multiple molecular targets of indole-3-carbinol, a chemopreventive anti-estrogen in breast cancer. ( Ashok, BT; Chen, YG; Garikapaty, VP; Liu, X; Mittelman, A; Roy, K; Seplowitz, R; Tiwari, RK; Tschorn, J, 2002) |
| "The high incidence of endometrial cancer in this strain of rats might be related to increased estrogen/progesterone ratio with aging." | 1.29 | Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indole-3-carbinol. ( Kojima, T; Mori, H; Tanaka, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashok, BT | 1 |
| Chen, YG | 1 |
| Liu, X | 1 |
| Garikapaty, VP | 1 |
| Seplowitz, R | 1 |
| Tschorn, J | 1 |
| Roy, K | 1 |
| Mittelman, A | 1 |
| Tiwari, RK | 2 |
| Brandi, G | 1 |
| Paiardini, M | 1 |
| Cervasi, B | 1 |
| Fiorucci, C | 1 |
| Filippone, P | 1 |
| De Marco, C | 1 |
| Zaffaroni, N | 1 |
| Magnani, M | 1 |
| Xue, L | 1 |
| Schaldach, CM | 1 |
| Janosik, T | 1 |
| Bergman, J | 1 |
| Bjeldanes, LF | 1 |
| Kojima, T | 1 |
| Tanaka, T | 1 |
| Mori, H | 1 |
| Guo, L | 1 |
| Bradlow, HL | 2 |
| Telang, NT | 2 |
| Osborne, MP | 2 |
| Katdare, M | 1 |
1 review available for indole-3-carbinol and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
Estradiol metabolism: an endocrine biomarker for modulation of human mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anticarcinogenic Agents; Benzo(a)pyrene; Biomarkers; Breast; Breas | 1997 |
5 other studies available for indole-3-carbinol and Hormone-Dependent Neoplasms
| Article | Year |
|---|---|
Multiple molecular targets of indole-3-carbinol, a chemopreventive anti-estrogen in breast cancer.
Topics: Anticarcinogenic Agents; Base Sequence; BRCA1 Protein; Breast Neoplasms; Carrier Proteins; Estrogen | 2002 |
A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle Proteins; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase | 2003 |
Effects of analogs of indole-3-carbinol cyclic trimerization product in human breast cancer cells.
Topics: Animals; Binding, Competitive; Breast Neoplasms; Cell Line, Tumor; Cytochrome P-450 CYP1A1; DNA, Neo | 2005 |
Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indole-3-carbinol.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Diet; Endometrial Neoplasms; Estradiol; Female; Hy | 1994 |
Selective responsiveness of human breast cancer cells to indole-3-carbinol, a chemopreventive agent.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Division; Cytochrome P-450 Enzyme System; Estradiol; | 1994 |