indole-3-carbinol has been researched along with Diabetic Glomerulosclerosis in 3 studies
indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetes was induced with streptozotocin in Cyp1a1mRen2 rats and hypertension was generated by inducing renin transgene expression with dietary indole-3-carbinol (I-3-C) for 28 weeks." | 3.80 | Tight blood glycaemic and blood pressure control in experimental diabetic nephropathy reduces extracellular matrix production without regression of fibrosis. ( Betz, B; Conway, BR; Dobyns, A; Dunbar, DR; Hughes, J; Manning, JR; Mullins, JJ; Sheldrake, TA, 2014) |
| "Hypertension is a prerequisite for advanced diabetic nephropathy in humans, so its rarity in typical rodent models may partly explain their resistance to nephropathy." | 1.38 | Hyperglycemia and renin-dependent hypertension synergize to model diabetic nephropathy. ( Bailey, MA; Bellamy, CO; Conway, BR; Dunbar, DR; Hughes, J; Manning, JR; Mullins, JJ; Rennie, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cairns, C | 1 |
| Conway, B | 1 |
| Conway, BR | 2 |
| Betz, B | 1 |
| Sheldrake, TA | 1 |
| Manning, JR | 2 |
| Dunbar, DR | 2 |
| Dobyns, A | 1 |
| Hughes, J | 2 |
| Mullins, JJ | 2 |
| Rennie, J | 1 |
| Bailey, MA | 1 |
| Bellamy, CO | 1 |
3 other studies available for indole-3-carbinol and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Modeling Human Diabetic Kidney Disease by Combining Hyperglycemia and Hypertension in a Transgenic Rodent Model.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inducers; Diabetes Mellitus, Experimental; | 2020 |
Tight blood glycaemic and blood pressure control in experimental diabetic nephropathy reduces extracellular matrix production without regression of fibrosis.
Topics: Albuminuria; Animals; Biomarkers; Blood Glucose; Blood Pressure; Cytochrome P-450 CYP1A1; Diabetes M | 2014 |
Hyperglycemia and renin-dependent hypertension synergize to model diabetic nephropathy.
Topics: Albuminuria; Animals; Comorbidity; Cytochrome P-450 CYP1A1; Diabetes Mellitus, Experimental; Diabeti | 2012 |