indole-3-carbinol has been researched along with Colorectal Neoplasms in 4 studies
indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The review is limited by the lack of bioavailability data in humans." | 6.44 | Putative mechanisms of action for indole-3-carbinol in the prevention of colorectal cancer. ( McGrath, DR; Spigelman, AD, 2008) |
| "Human colorectal cancer cell lines DLD1, HCT116, HT-29, LS513, and RKO were treated with indole-3-carbinol or vehicle." | 4.93 | Indole-3-carbinol induces tumor cell death: function follows form. ( Carney, PR; Geiger, P; Kennedy, GD; Megna, BW; Nukaya, M, 2016) |
| "We used a mouse model of colitis-associated colorectal tumorigenesis that employs treatment with azoxymethane and dextran sodium sulfate." | 3.83 | The Aryl Hydrocarbon Receptor is a Repressor of Inflammation-associated Colorectal Tumorigenesis in Mouse. ( Balbo, S; Bradfield, CA; Carney, PR; Dator, R; Díaz-Díaz, CJ; Geiger, PG; Kennedy, GD; Megna, BW; Nukaya, M; Ronnekleiv-Kelly, SM, 2016) |
| " The review is limited by the lack of bioavailability data in humans." | 2.44 | Putative mechanisms of action for indole-3-carbinol in the prevention of colorectal cancer. ( McGrath, DR; Spigelman, AD, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, JY | 1 |
| Lim, HM | 1 |
| Lee, CM | 1 |
| Park, SH | 1 |
| Nam, MJ | 1 |
| Díaz-Díaz, CJ | 1 |
| Ronnekleiv-Kelly, SM | 1 |
| Nukaya, M | 2 |
| Geiger, PG | 1 |
| Balbo, S | 1 |
| Dator, R | 1 |
| Megna, BW | 2 |
| Carney, PR | 2 |
| Bradfield, CA | 1 |
| Kennedy, GD | 2 |
| Geiger, P | 1 |
| McGrath, DR | 1 |
| Spigelman, AD | 1 |
2 reviews available for indole-3-carbinol and Colorectal Neoplasms
| Article | Year |
|---|---|
Indole-3-carbinol induces tumor cell death: function follows form.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Bi | 2016 |
Putative mechanisms of action for indole-3-carbinol in the prevention of colorectal cancer.
Topics: Animals; Anticarcinogenic Agents; Colorectal Neoplasms; Glucosinolates; Humans; Indoles; Vegetables | 2008 |
2 other studies available for indole-3-carbinol and Colorectal Neoplasms
| Article | Year |
|---|---|
Indole-3-carbinol inhibits the proliferation of colorectal carcinoma LoVo cells through activation of the apoptotic signaling pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle; Cell Line, | 2021 |
The Aryl Hydrocarbon Receptor is a Repressor of Inflammation-associated Colorectal Tumorigenesis in Mouse.
Topics: Animals; Azoxymethane; Colitis; Colorectal Neoplasms; Dextran Sulfate; DNA Damage; Gene Expression; | 2016 |