Page last updated: 2024-10-29

indole-3-carbinol and Cocarcinogenesis

indole-3-carbinol has been researched along with Cocarcinogenesis in 7 studies

indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.

Cocarcinogenesis: The combination of two or more different factors in the production of cancer.

Research Excerpts

ExcerptRelevanceReference
" To provide quantitative potency information for these opposing activities, detailed tumor dose-response studies were performed with AFB1 (10-400 ppb) and I3C (0-4,000 ppm)."1.28Tumor dose-response studies with aflatoxin B1 and the ambivalent modulator indole-3-carbinol: inhibitory versus promotional potency. ( Bailey, GS; Dashwood, RH; Fong, AT; Hendricks, JD, 1990)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's3 (42.86)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Moura, NA1
Caetano, BFR1
de Moraes, LN1
Carvalho, RF1
Rodrigues, MAM1
Barbisan, LF1
Yamamoto, R1
Shimamoto, K1
Ishii, Y1
Kimura, M1
Fujii, Y1
Morita, R1
Suzuki, K1
Shibutani, M1
Mitsumori, K1
Gallagher, EP1
Dashwood, RH2
Oganesian, A1
Hendricks, JD2
Pereira, CB1
Orner, GA1
Bailey, GS2
Williams, DE1
Fong, AT1
Pence, BC1
Buddingh, F1
Yang, SP1

Reviews

1 review available for indole-3-carbinol and Cocarcinogenesis

ArticleYear
Indole-3-carbinol: anticarcinogen or tumor promoter in brassica vegetables?
    Chemico-biological interactions, 1998, Mar-12, Volume: 110, Issue:1-2

    Topics: Animals; Anticarcinogenic Agents; Brassica; Carcinogens; Cocarcinogenesis; Databases as Topic; Human

1998

Other Studies

6 other studies available for indole-3-carbinol and Cocarcinogenesis

ArticleYear
Enhancement of colon carcinogenesis by the combination of indole-3 carbinol and synbiotics in hemin-fed rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 112

    Topics: Adaptor Proteins, Signal Transducing; Animals; Anticarcinogenic Agents; Caco-2 Cells; Cadherins; Car

2018
Involvement of PTEN/Akt signaling and oxidative stress on indole-3-carbinol (I3C)-induced hepatocarcinogenesis in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2013, Volume: 65, Issue:6

    Topics: Animals; Body Weight; Cocarcinogenesis; Diethylnitrosamine; DNA Damage; Immunohistochemistry; Indole

2013
Using salmonid microarrays to understand the dietary modulation of carcinogenesis in rainbow trout.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 90, Issue:1

    Topics: Aflatoxin B1; Animals; Carcinogens; Cocarcinogenesis; Disease Models, Animal; Dose-Response Relation

2006
Potency of dietary indole-3-carbinol as a promoter of aflatoxin B1-initiated hepatocarcinogenesis: results from a 9000 animal tumor study.
    Carcinogenesis, 1999, Volume: 20, Issue:3

    Topics: Aflatoxin B1; Animals; Carcinogens; Cocarcinogenesis; Diet; Disease Models, Animal; Dose-Response Re

1999
Tumor dose-response studies with aflatoxin B1 and the ambivalent modulator indole-3-carbinol: inhibitory versus promotional potency.
    Basic life sciences, 1990, Volume: 52

    Topics: Aflatoxin B1; Aflatoxins; Animals; Cocarcinogenesis; Dose-Response Relationship, Drug; Drug Administ

1990
Multiple dietary factors in the enhancement of dimethylhydrazine carcinogenesis: main effect of indole-3-carbinol.
    Journal of the National Cancer Institute, 1986, Volume: 77, Issue:1

    Topics: Adenocarcinoma; Analysis of Variance; Animal Feed; Animals; Aryl Hydrocarbon Hydroxylases; Body Weig

1986