indole-3-carbinol has been researched along with Cirrhosis in 6 studies
indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetes was induced with streptozotocin in Cyp1a1mRen2 rats and hypertension was generated by inducing renin transgene expression with dietary indole-3-carbinol (I-3-C) for 28 weeks." | 3.80 | Tight blood glycaemic and blood pressure control in experimental diabetic nephropathy reduces extracellular matrix production without regression of fibrosis. ( Betz, B; Conway, BR; Dobyns, A; Dunbar, DR; Hughes, J; Manning, JR; Mullins, JJ; Sheldrake, TA, 2014) |
| "Indole-3-carbinol (I3C), a monomer component extracted from leaves and stems of cruciferous vegetables, has inhibitory effects on tumors, obesity, and liver fibrosis, but its effects on the development of cardiac remodeling remain completely unknown." | 3.79 | Indole-3-carbinol protects against pressure overload induced cardiac remodeling via activating AMPK-α. ( Bian, Z; Deng, W; Guo, H; Li, H; Shen, D; Tang, Q; Yuan, Y; Zhang, R; Zhang, Y; Zhou, H; Zong, J, 2013) |
| "Hypertension is a prerequisite for advanced diabetic nephropathy in humans, so its rarity in typical rodent models may partly explain their resistance to nephropathy." | 1.38 | Hyperglycemia and renin-dependent hypertension synergize to model diabetic nephropathy. ( Bailey, MA; Bellamy, CO; Conway, BR; Dunbar, DR; Hughes, J; Manning, JR; Mullins, JJ; Rennie, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cairns, C | 1 |
| Conway, B | 1 |
| Guzmán-Navarro, G | 1 |
| León, MB | 1 |
| Martín-Estal, I | 1 |
| Durán, RC | 1 |
| Villarreal-Alvarado, L | 1 |
| Vaquera-Vázquez, A | 1 |
| Cuevas-Cerda, T | 1 |
| Garza-García, K | 1 |
| Cuervo-Pérez, LE | 1 |
| Barbosa-Quintana, Á | 1 |
| Pérez-Saucedo, JE | 1 |
| Lara-Díaz, VJ | 1 |
| Castorena-Torres, F | 1 |
| Deng, W | 1 |
| Zong, J | 1 |
| Bian, Z | 1 |
| Zhou, H | 1 |
| Yuan, Y | 1 |
| Zhang, R | 1 |
| Guo, H | 1 |
| Zhang, Y | 1 |
| Shen, D | 1 |
| Li, H | 1 |
| Tang, Q | 1 |
| Conway, BR | 2 |
| Betz, B | 1 |
| Sheldrake, TA | 1 |
| Manning, JR | 2 |
| Dunbar, DR | 2 |
| Dobyns, A | 1 |
| Hughes, J | 2 |
| Mullins, JJ | 3 |
| Peters, J | 1 |
| Schlüter, T | 1 |
| Riegel, T | 1 |
| Peters, BS | 1 |
| Beineke, A | 1 |
| Maschke, U | 1 |
| Hosten, N | 1 |
| Rettig, R | 1 |
| Rennie, J | 1 |
| Bailey, MA | 1 |
| Bellamy, CO | 1 |
6 other studies available for indole-3-carbinol and Cirrhosis
| Article | Year |
|---|---|
Modeling Human Diabetic Kidney Disease by Combining Hyperglycemia and Hypertension in a Transgenic Rodent Model.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inducers; Diabetes Mellitus, Experimental; | 2020 |
Prenatal indole-3-carbinol administration activates aryl hydrocarbon receptor-responsive genes and attenuates lung injury in a bronchopulmonary dysplasia model.
Topics: Animals; Animals, Newborn; Bronchopulmonary Dysplasia; Cytokines; Disease Models, Animal; Female; Fi | 2021 |
Indole-3-carbinol protects against pressure overload induced cardiac remodeling via activating AMPK-α.
Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Cardiomegaly; Fibrosis; Heart; Indoles; Male; M | 2013 |
Tight blood glycaemic and blood pressure control in experimental diabetic nephropathy reduces extracellular matrix production without regression of fibrosis.
Topics: Albuminuria; Animals; Biomarkers; Blood Glucose; Blood Pressure; Cytochrome P-450 CYP1A1; Diabetes M | 2014 |
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism.
Topics: Administration, Oral; Aldosterone; Animals; Cardiomegaly; Collagen Type I; Cytochrome P-450 CYP1A1; | 2009 |
Hyperglycemia and renin-dependent hypertension synergize to model diabetic nephropathy.
Topics: Albuminuria; Animals; Comorbidity; Cytochrome P-450 CYP1A1; Diabetes Mellitus, Experimental; Diabeti | 2012 |