indole-3-carbinol has been researched along with Cell Transformation, Neoplastic in 13 studies
indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the chemopreventive efficacy of indole-3-carbinol (I3C), a phytochemical found in cruciferous vegetables, to inhibit tobacco carcinogen-induced lung adenocarcinoma in A/J mice when given following post-initiation or progression protocol." | 7.77 | Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis. ( Kassie, F; Melkamu, T; Qian, X; Upadhyaya, P, 2011) |
| "Chronic inflammation is an important risk factor for lung cancer." | 5.42 | Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators. ( Kassie, F; Luo, X; Molla, K; O Sullivan, G; Qian, X; Song, JM; Teferi, F; Upadhyaya, P, 2015) |
| "We studied the chemopreventive efficacy of indole-3-carbinol (I3C), a phytochemical found in cruciferous vegetables, to inhibit tobacco carcinogen-induced lung adenocarcinoma in A/J mice when given following post-initiation or progression protocol." | 3.77 | Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis. ( Kassie, F; Melkamu, T; Qian, X; Upadhyaya, P, 2011) |
| "Chronic inflammation is an important risk factor for lung cancer." | 1.42 | Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators. ( Kassie, F; Luo, X; Molla, K; O Sullivan, G; Qian, X; Song, JM; Teferi, F; Upadhyaya, P, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, JM | 1 |
| Qian, X | 2 |
| Molla, K | 1 |
| Teferi, F | 1 |
| Upadhyaya, P | 3 |
| O Sullivan, G | 1 |
| Luo, X | 2 |
| Kassie, F | 3 |
| Moiseeva, EP | 1 |
| Manson, MM | 2 |
| Melkamu, T | 2 |
| Endalew, A | 1 |
| Hecht, SS | 1 |
| Suzui, M | 1 |
| Inamine, M | 1 |
| Kaneshiro, T | 1 |
| Morioka, T | 1 |
| Yoshimi, N | 1 |
| Suzuki, R | 1 |
| Kohno, H | 1 |
| Tanaka, T | 1 |
| Cope, RB | 1 |
| Loehr, C | 1 |
| Dashwood, R | 1 |
| Kerkvliet, NI | 1 |
| Telang, NT | 3 |
| Katdare, M | 1 |
| Bradlow, HL | 3 |
| Osborne, MP | 3 |
| Fishman, J | 1 |
| Inoue, S | 1 |
| Hudson, EA | 1 |
| Howells, L | 1 |
| Ball, HW | 1 |
| Pfeifer, AM | 1 |
| Jin, L | 1 |
| Qi, M | 1 |
| Chen, DZ | 1 |
| Anderson, A | 1 |
| Yang, GY | 1 |
| Arbeit, JM | 1 |
| Auborn, KJ | 1 |
| Shukla, Y | 1 |
| Singh, A | 1 |
| Srivastava, B | 1 |
| He, YH | 1 |
| Friesen, MD | 1 |
| Ruch, RJ | 1 |
| Schut, HA | 1 |
| Suto, A | 1 |
| Wong, GY | 1 |
1 review available for indole-3-carbinol and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Dietary chemopreventive phytochemicals: too little or too much?
Topics: Animals; Catechin; Cell Transformation, Neoplastic; Curcumin; Diet; Food; Fruit; Genistein; Humans; | 2009 |
12 other studies available for indole-3-carbinol and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators.
Topics: Animals; Anticarcinogenic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Tr | 2015 |
Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Be | 2010 |
Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anticarcinogenic Agents; Carcinogens; Cell Growth P | 2011 |
Indole-3-carbinol inhibits the growth of human colon carcinoma cells but enhances the tumor multiplicity and volume of azoxymethane-induced rat colon carcinogenesis.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antioxidants; Apoptosis; Cell Cycle; Cell Proliferati | 2005 |
Ultraviolet radiation-induced non-melanoma skin cancer in the Crl:SKH1:hr-BR hairless mouse: augmentation of tumor multiplicity by chlorophyllin and protection by indole-3-carbinol.
Topics: Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Chlorophyllides; Diet; Female; In | 2006 |
Inhibition of proliferation and modulation of estradiol metabolism: novel mechanisms for breast cancer prevention by the phytochemical indole-3-carbinol.
Topics: Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Breast; Breast Neoplasms; Carcinogens; Cell Divi | 1997 |
Negative growth regulation of oncogene-transformed mammary epithelial cells by tumor inhibitors.
Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Cell Division; Cell Line; Cell Transformation, | 1997 |
Mechanisms of action of indole-3-carbinol as a chemopreventive agent.
Topics: 3T3 Cells; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Enzyme Inhibitors; Hum | 1998 |
Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice.
Topics: Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Estrogen Antagonists; Female; Gen | 1999 |
Inhibition of carcinogen-induced activity of gamma-glutamyl transpeptidase by certain dietary constituents in mouse skin.
Topics: Allyl Compounds; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Die | 1999 |
Indole-3-carbinol as a chemopreventive agent in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenesis: inhibition of PhIP-DNA adduct formation, acceleration of PhIP metabolism, and induction of cytochrome P450 in female F344 rats.
Topics: Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; D | 2000 |
Persistent estrogen responsiveness of ras oncogene-transformed mouse mammary epithelial cells.
Topics: Animals; Biomarkers, Tumor; Biotransformation; Cell Division; Cell Transformation, Neoplastic; Epith | 1992 |