Page last updated: 2024-10-29

indole-3-carbinol and Cardiomegaly

indole-3-carbinol has been researched along with Cardiomegaly in 3 studies

indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"Indole-3-carbinol (I3C), a monomer component extracted from leaves and stems of cruciferous vegetables, has inhibitory effects on tumors, obesity, and liver fibrosis, but its effects on the development of cardiac remodeling remain completely unknown."3.79Indole-3-carbinol protects against pressure overload induced cardiac remodeling via activating AMPK-α. ( Bian, Z; Deng, W; Guo, H; Li, H; Shen, D; Tang, Q; Yuan, Y; Zhang, R; Zhang, Y; Zhou, H; Zong, J, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Heijnen, BF1
Pelkmans, LP1
Danser, AH1
Garrelds, IM1
Mullins, JJ2
De Mey, JG1
Struijker-Boudier, HA1
Janssen, BJ1
Deng, W1
Zong, J1
Bian, Z1
Zhou, H1
Yuan, Y1
Zhang, R1
Guo, H1
Zhang, Y1
Shen, D1
Li, H1
Tang, Q1
Peters, J1
Schlüter, T1
Riegel, T1
Peters, BS1
Beineke, A1
Maschke, U1
Hosten, N1
Rettig, R1

Other Studies

3 other studies available for indole-3-carbinol and Cardiomegaly

ArticleYear
Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2014, Volume: 15, Issue:1

    Topics: Aging; Animals; Cardiomegaly; Cytochrome P-450 CYP1A1; Heart; Hypertension; Indoles; Male; Myocardiu

2014
Indole-3-carbinol protects against pressure overload induced cardiac remodeling via activating AMPK-α.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:9

    Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Cardiomegaly; Fibrosis; Heart; Indoles; Male; M

2013
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5

    Topics: Administration, Oral; Aldosterone; Animals; Cardiomegaly; Collagen Type I; Cytochrome P-450 CYP1A1;

2009