indole-3-carbinol has been researched along with Cardiomegaly in 3 studies
indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indole-3-carbinol (I3C), a monomer component extracted from leaves and stems of cruciferous vegetables, has inhibitory effects on tumors, obesity, and liver fibrosis, but its effects on the development of cardiac remodeling remain completely unknown." | 3.79 | Indole-3-carbinol protects against pressure overload induced cardiac remodeling via activating AMPK-α. ( Bian, Z; Deng, W; Guo, H; Li, H; Shen, D; Tang, Q; Yuan, Y; Zhang, R; Zhang, Y; Zhou, H; Zong, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heijnen, BF | 1 |
| Pelkmans, LP | 1 |
| Danser, AH | 1 |
| Garrelds, IM | 1 |
| Mullins, JJ | 2 |
| De Mey, JG | 1 |
| Struijker-Boudier, HA | 1 |
| Janssen, BJ | 1 |
| Deng, W | 1 |
| Zong, J | 1 |
| Bian, Z | 1 |
| Zhou, H | 1 |
| Yuan, Y | 1 |
| Zhang, R | 1 |
| Guo, H | 1 |
| Zhang, Y | 1 |
| Shen, D | 1 |
| Li, H | 1 |
| Tang, Q | 1 |
| Peters, J | 1 |
| Schlüter, T | 1 |
| Riegel, T | 1 |
| Peters, BS | 1 |
| Beineke, A | 1 |
| Maschke, U | 1 |
| Hosten, N | 1 |
| Rettig, R | 1 |
3 other studies available for indole-3-carbinol and Cardiomegaly
| Article | Year |
|---|---|
Cardiac remodeling during and after renin-angiotensin system stimulation in Cyp1a1-Ren2 transgenic rats.
Topics: Aging; Animals; Cardiomegaly; Cytochrome P-450 CYP1A1; Heart; Hypertension; Indoles; Male; Myocardiu | 2014 |
Indole-3-carbinol protects against pressure overload induced cardiac remodeling via activating AMPK-α.
Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Cardiomegaly; Fibrosis; Heart; Indoles; Male; M | 2013 |
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism.
Topics: Administration, Oral; Aldosterone; Animals; Cardiomegaly; Collagen Type I; Cytochrome P-450 CYP1A1; | 2009 |