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indole-3-carbinol and Body Weight

indole-3-carbinol has been researched along with Body Weight in 25 studies

indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"This study investigated the effects of indole-3-carbinol (I3C), a cruciferous vegetable derivative, on obesity and its associated factors in high-fat-diet-induced obese (DIO) mice."7.77Antiobesity activities of indole-3-carbinol in high-fat-diet-induced obese mice. ( Chan, MH; Chang, HP; Chen, YH; Chiu, YS; Wang, ML, 2011)
"The histopathologic changes of intestinal lymphangiectasis and lipidosis in this study share similarities with intestinal lymphangiectasia as observed in humans and dogs."5.38Intestinal lymphangiectasis and lipidosis in rats following subchronic exposure to indole-3-carbinol via oral gavage. ( Boyle, MC; Crabbs, TA; Hill, GD; Lieuallen, WG; Malarkey, DE; Nyska, A; Painter, JT; Wyde, ME, 2012)
"Indole-3-carbinol (I3C), a monomer component extracted from leaves and stems of cruciferous vegetables, has inhibitory effects on tumors, obesity, and liver fibrosis, but its effects on the development of cardiac remodeling remain completely unknown."3.79Indole-3-carbinol protects against pressure overload induced cardiac remodeling via activating AMPK-α. ( Bian, Z; Deng, W; Guo, H; Li, H; Shen, D; Tang, Q; Yuan, Y; Zhang, R; Zhang, Y; Zhou, H; Zong, J, 2013)
"This study investigated the effects of indole-3-carbinol (I3C), a compound from cruciferous vegetables, on various parameters related to obesity, in particular, the parameters of infiltration by macrophages and of inflammatory cytokines expressed during the co-culture of adipocytes and macrophages."3.77Suppression of inflammation-associated factors by indole-3-carbinol in mice fed high-fat diets and in isolated, co-cultured macrophages and adipocytes. ( Chan, MH; Chang, HP; Chen, YH; Hsu, CY; Liu, ME; Wang, ML, 2011)
"This study investigated the effects of indole-3-carbinol (I3C), a cruciferous vegetable derivative, on obesity and its associated factors in high-fat-diet-induced obese (DIO) mice."3.77Antiobesity activities of indole-3-carbinol in high-fat-diet-induced obese mice. ( Chan, MH; Chang, HP; Chen, YH; Chiu, YS; Wang, ML, 2011)
"Male Sprague-Dawley rats were treated orally with indole-3-carbinol (13C) for 7 wk at levels of 150, 100, and 50 mg/kg body weight."3.71Effects of indole-3-carbinol on immune responses, aberrant crypt foci, and colonic crypt cell proliferation in rats. ( Exon, JH; Hendrix, K; Magnuson, BA; South, EH, 2001)
"The histopathologic changes of intestinal lymphangiectasis and lipidosis in this study share similarities with intestinal lymphangiectasia as observed in humans and dogs."1.38Intestinal lymphangiectasis and lipidosis in rats following subchronic exposure to indole-3-carbinol via oral gavage. ( Boyle, MC; Crabbs, TA; Hill, GD; Lieuallen, WG; Malarkey, DE; Nyska, A; Painter, JT; Wyde, ME, 2012)
"Polyarteritis nodosa is a necrotizing vasculitis of medium-sized arteries of unknown origin."1.36The renin-angiotensin system as a primary cause of polyarteritis nodosa in rats. ( Beineke, A; Kuttler, B; Lorenz, G; Mullins, JJ; Nicolai, O; Peters, BS; Peters, J; Rettig, R; Thiele, A, 2010)
" In Experiment 2, a total of 45 female SD rats were dosed with DEN (100 mg/kg, i."1.29Biphasic modifying effect of indole-3-carbinol on diethylnitrosamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley rats. ( Ahn, B; Bae, JH; Han, BS; Jang, JJ; Kim, DJ; Lee, KK, 1994)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's5 (20.00)18.2507
2000's8 (32.00)29.6817
2010's9 (36.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Mohamad, KA1
El-Naga, RN1
Wahdan, SA1
Donia, T1
Gerges, MN1
Mohamed, TM1
Deng, W1
Zong, J1
Bian, Z1
Zhou, H1
Yuan, Y1
Zhang, R1
Guo, H1
Zhang, Y1
Shen, D1
Li, H1
Tang, Q1
Kim, JK1
Gallaher, DD1
Chen, C1
Gallaher, CM1
Yao, D1
Trudo, SP1
Peters, BS1
Kuttler, B1
Beineke, A1
Lorenz, G1
Thiele, A1
Nicolai, O1
Rettig, R1
Mullins, JJ1
Peters, J1
Shimamoto, K3
Dewa, Y2
Kemmochi, S2
Taniai, E2
Hayashi, H2
Imaoka, M2
Shibutani, M3
Mitsumori, K3
Chang, HP2
Wang, ML2
Hsu, CY1
Liu, ME1
Chan, MH2
Chen, YH2
Chiu, YS1
Ishii, Y2
Morita, R2
Kuwata, K1
Suzuki, K2
Boyle, MC1
Crabbs, TA1
Wyde, ME1
Painter, JT1
Hill, GD1
Malarkey, DE1
Lieuallen, WG1
Nyska, A1
Yamamoto, R1
Kimura, M1
Fujii, Y1
Gao, X1
Petroff, BK1
Oluola, O1
Georg, G1
Terranova, PF1
Rozman, KK1
Nemeti, B1
Csanaky, I1
Gregus, Z1
Kishida, T1
Nagamoto, M1
Ohtsu, Y1
Watakabe, M1
Ohshima, D1
Nashiki, K1
Mizushige, T1
Izumi, T1
Obata, A1
Ebihara, K1
Kim, DJ2
Lee, KK1
Han, BS1
Ahn, B2
Bae, JH2
Jang, JJ2
He, YH1
Schut, HA1
Malejka-Giganti, D1
Niehans, GA1
Reichert, MA1
Bliss, RL1
Exon, JH1
South, EH1
Magnuson, BA1
Hendrix, K1
Kang, JS1
Nam, KT1
Kim, KS1
Choi, M1
Jang, DD1
Ramaiah, SK1
Apte, U1
Mehendale, HM1
Stoner, G1
Casto, B1
Ralston, S1
Roebuck, B1
Pereira, C1
Bailey, G1
Tanaka, T1
Kojima, T1
Morishita, Y1
Mori, H1
Wortelboer, HM1
van der Linden, EC1
de Kruif, CA1
Noordhoek, J1
Blaauboer, BJ1
van Bladeren, PJ1
Falke, HE1
Cho, KJ1
Lee, YS1
Pence, BC1
Buddingh, F1
Yang, SP1

Other Studies

25 other studies available for indole-3-carbinol and Body Weight

ArticleYear
Neuroprotective effects of indole-3-carbinol on the rotenone rat model of Parkinson's disease: Impact of the SIRT1-AMPK signaling pathway.
    Toxicology and applied pharmacology, 2022, 01-15, Volume: 435

    Topics: alpha-Synuclein; Animals; Body Weight; Catalepsy; Dopamine; Indoles; Male; MAP Kinase Signaling Syst

2022
Anticancer Effects of Combination of Indole-3-Carbinol and Hydroxychloroquine on Ehrlich Ascites Carcinoma via Targeting Autophagy and Apoptosis.
    Nutrition and cancer, 2022, Volume: 74, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Ascites; Autophagy; Body Weight; Carcinoma; Cell Line, Tu

2022
Indole-3-carbinol protects against pressure overload induced cardiac remodeling via activating AMPK-α.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:9

    Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Cardiomegaly; Fibrosis; Heart; Indoles; Male; M

2013
Phenethyl isothiocyanate and indole-3-carbinol from cruciferous vegetables, but not furanocoumarins from apiaceous vegetables, reduced PhIP-induced DNA adducts in Wistar rats.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Arylsulfotransferase; Body Weight; Colon; Cytochrome P-450 CYP1A1;

2016
The renin-angiotensin system as a primary cause of polyarteritis nodosa in rats.
    Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:6A

    Topics: Animals; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Antinuclear; Blood Pressure; Body Weigh

2010
Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats.
    Archives of toxicology, 2011, Volume: 85, Issue:9

    Topics: Animals; beta-Naphthoflavone; Body Weight; Cytochrome P-450 CYP1A1; Diethylnitrosamine; Enzyme Induc

2011
Suppression of inflammation-associated factors by indole-3-carbinol in mice fed high-fat diets and in isolated, co-cultured macrophages and adipocytes.
    International journal of obesity (2005), 2011, Volume: 35, Issue:12

    Topics: Adipocytes; Adipose Tissue; Animals; Anti-Obesity Agents; Body Weight; Coculture Techniques; Diet, H

2011
Antiobesity activities of indole-3-carbinol in high-fat-diet-induced obese mice.
    Nutrition (Burbank, Los Angeles County, Calif.), 2011, Volume: 27, Issue:4

    Topics: Acetyl-CoA Carboxylase; Adiponectin; Adipose Tissue; Animals; Anti-Obesity Agents; Blood Glucose; Bo

2011
Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine.
    Toxicology, 2011, May-10, Volume: 283, Issue:2-3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Body Weight; Carcinogens; Deoxyguanosine; Diethylnitrosamine;

2011
Intestinal lymphangiectasis and lipidosis in rats following subchronic exposure to indole-3-carbinol via oral gavage.
    Toxicologic pathology, 2012, Volume: 40, Issue:4

    Topics: Administration, Oral; Animals; Body Weight; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Female

2012
Involvement of PTEN/Akt signaling and oxidative stress on indole-3-carbinol (I3C)-induced hepatocarcinogenesis in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2013, Volume: 65, Issue:6

    Topics: Animals; Body Weight; Cocarcinogenesis; Diethylnitrosamine; DNA Damage; Immunohistochemistry; Indole

2013
Endocrine disruption by indole-3-carbinol and tamoxifen: blockage of ovulation.
    Toxicology and applied pharmacology, 2002, Sep-15, Volume: 183, Issue:3

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Female; Gonadotropins; Indoles; Organ Size;

2002
Arsenate reduction in human erythrocytes and rats--testing the role of purine nucleoside phosphorylase.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 74, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Blotting, Western; Body Weight; Bone Density; Calcitriol; Colon; C

2003
Lack of an inducible effect of dietary soy isoflavones on the mRNA abundance of hepatic cytochrome P-450 isozymes in rats.
    Bioscience, biotechnology, and biochemistry, 2004, Volume: 68, Issue:3

    Topics: Animals; Body Weight; Cyclophilins; Cytochrome P-450 Enzyme System; Eating; Enzyme Induction; Female

2004
Biphasic modifying effect of indole-3-carbinol on diethylnitrosamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley rats.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Body Weight; Diethylnitrosamine; Enzyme Inducti

1994
Inhibition of DNA adduct formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3-methylimidazo[4,5-f]quinoline by dietary indole-3-carbinol in female rats.
    Journal of biochemical and molecular toxicology, 1999, Volume: 13, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Diet; DNA Adducts; Female; Imidazoles; I

1999
Post-initiation treatment of rats with indole-3-carbinol or beta-naphthoflavone does not suppress 7, 12-dimethylbenz[a]anthracene-induced mammary gland carcinogenesis.
    Cancer letters, 2000, Nov-28, Volume: 160, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; beta-Naphthoflavone; Body Weight

2000
Effects of indole-3-carbinol on immune responses, aberrant crypt foci, and colonic crypt cell proliferation in rats.
    Journal of toxicology and environmental health. Part A, 2001, Apr-06, Volume: 62, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Biomarkers; Body Weight; Carcinogens; Cell Division;

2001
Post-initiation treatment of Indole-3-carbinol did not suppress N-methyl-N-nitrosourea induced mammary carcinogenesis in rats.
    Cancer letters, 2001, Aug-28, Volume: 169, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Female; Indoles; Mammary Neoplasms, Anim

2001
Cytochrome P4502E1 induction increases thioacetamide liver injury in diet-restricted rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:8

    Topics: Animals; Antioxidants; Blotting, Western; Body Weight; Carbon Tetrachloride; Carcinogens; Chemical a

2001
Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol.
    Carcinogenesis, 2002, Volume: 23, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Anticarcinogenic Agents; Azoxymethane; Body

2002
Inhibitory effects of the natural products indole-3-carbinol and sinigrin during initiation and promotion phases of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.
    Japanese journal of cancer research : Gann, 1992, Volume: 83, Issue:8

    Topics: 4-Nitroquinoline-1-oxide; Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Carcinoma, Sq

1992
Effects of indole-3-carbinol on biotransformation enzymes in the rat: in vivo changes in liver and small intestinal mucosa in comparison with primary hepatocyte cultures.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1992, Volume: 30, Issue:7

    Topics: Administration, Oral; Animals; Biotransformation; Body Weight; Cells, Cultured; Cytochrome P-450 Enz

1992
Modifying responses of allyl sulfide, indole-3-carbinol and germanium in a rat multi-organ carcinogenesis model.
    Carcinogenesis, 1991, Volume: 12, Issue:4

    Topics: Allyl Compounds; Animals; Body Weight; Diethylnitrosamine; Disease Models, Animal; Germanium; Indole

1991
Multiple dietary factors in the enhancement of dimethylhydrazine carcinogenesis: main effect of indole-3-carbinol.
    Journal of the National Cancer Institute, 1986, Volume: 77, Issue:1

    Topics: Adenocarcinoma; Analysis of Variance; Animal Feed; Animals; Aryl Hydrocarbon Hydroxylases; Body Weig

1986