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indole-3-carbinol and Animal Mammary Carcinoma

indole-3-carbinol has been researched along with Animal Mammary Carcinoma in 3 studies

indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.

Research Excerpts

ExcerptRelevanceReference
" We tested the hypothesis that indole-3-carbinol (I3C), the hydrolysis product of glucosinolates occurring in cruciferous vegetables, may protect against ET-743-induced hepatotoxicity in the female Wistar rat, the animal species with the highest sensitivity toward the adverse hepatic effect of this drug."1.32Dietary agent indole-3-carbinol protects female rats against the hepatotoxicity of the antitumor drug ET-743 (trabectidin) without compromising efficacy in a rat mammary carcinoma. ( Colombo, T; D'Incalci, M; Donald, S; Falcioni, C; Gescher, AJ; Greaves, P; Jimeno, J; Manson, MM; Steward, WP; Verschoyle, RD; Zaffaroni, M; Zucchetti, M, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Donald, S1
Verschoyle, RD1
Greaves, P1
Colombo, T1
Zucchetti, M1
Falcioni, C1
Zaffaroni, M1
D'Incalci, M1
Manson, MM1
Jimeno, J1
Steward, WP1
Gescher, AJ1
Malejka-Giganti, D1
Parkin, DR1
Bennett, KK1
Lu, Y1
Decker, RW1
Niehans, GA1
Bliss, RL1
Kang, JS1
Kim, DJ1
Ahn, B1
Nam, KT1
Kim, KS1
Choi, M1
Jang, DD1

Other Studies

3 other studies available for indole-3-carbinol and Animal Mammary Carcinoma

ArticleYear
Dietary agent indole-3-carbinol protects female rats against the hepatotoxicity of the antitumor drug ET-743 (trabectidin) without compromising efficacy in a rat mammary carcinoma.
    International journal of cancer, 2004, Oct-10, Volume: 111, Issue:6

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Alkylating; Antioxidants; Chemoprevention; Die

2004
Suppression of mammary gland carcinogenesis by post-initiation treatment of rats with tamoxifen or indole-3-carbinol or their combination.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2007, Volume: 16, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Drug Therapy, Combination; Female; Indoles; Mammary Neoplasms, Ani

2007
Post-initiation treatment of Indole-3-carbinol did not suppress N-methyl-N-nitrosourea induced mammary carcinogenesis in rats.
    Cancer letters, 2001, Aug-28, Volume: 169, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Female; Indoles; Mammary Neoplasms, Anim

2001