indole-3-carbinol has been researched along with Albuminuria in 4 studies
indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant hypertension was induced in Cyp1a1-Ren-2 transgenic rats by activation of the renin gene using indole-3-carbinol (I3C), a natural xenobiotic." | 3.83 | Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats. ( Červenka, L; Doleželová, Š; Falck, JR; Husková, Z; Imig, JD; Jíchová, Š; Kompanowska-Jezierska, E; Kopkan, L; Kramer, HJ; Kujal, P; Neckář, J; Reddy, RN; Sadowski, J; Vernerová, Z, 2016) |
| "Diabetes was induced with streptozotocin in Cyp1a1mRen2 rats and hypertension was generated by inducing renin transgene expression with dietary indole-3-carbinol (I-3-C) for 28 weeks." | 3.80 | Tight blood glycaemic and blood pressure control in experimental diabetic nephropathy reduces extracellular matrix production without regression of fibrosis. ( Betz, B; Conway, BR; Dobyns, A; Dunbar, DR; Hughes, J; Manning, JR; Mullins, JJ; Sheldrake, TA, 2014) |
| "The present study was performed to assess the effects of the platelet-derived growth factor (PDGF) receptor kinase inhibitor imatinib mesylate on the renal morphological changes occurring during the development of malignant hypertension in transgenic rats with inducible expression of the Ren2 gene [TGR(Cyp1a1Ren2)]." | 3.78 | Imatinib ameliorates renal morphological changes in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension. ( Graciano, ML; Mitchell, KD, 2012) |
| "Hypertension is a prerequisite for advanced diabetic nephropathy in humans, so its rarity in typical rodent models may partly explain their resistance to nephropathy." | 1.38 | Hyperglycemia and renin-dependent hypertension synergize to model diabetic nephropathy. ( Bailey, MA; Bellamy, CO; Conway, BR; Dunbar, DR; Hughes, J; Manning, JR; Mullins, JJ; Rennie, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Conway, BR | 2 |
| Betz, B | 1 |
| Sheldrake, TA | 1 |
| Manning, JR | 2 |
| Dunbar, DR | 2 |
| Dobyns, A | 1 |
| Hughes, J | 2 |
| Mullins, JJ | 2 |
| Jíchová, Š | 1 |
| Kopkan, L | 1 |
| Husková, Z | 1 |
| Doleželová, Š | 1 |
| Neckář, J | 1 |
| Kujal, P | 1 |
| Vernerová, Z | 1 |
| Kramer, HJ | 1 |
| Sadowski, J | 1 |
| Kompanowska-Jezierska, E | 1 |
| Reddy, RN | 1 |
| Falck, JR | 1 |
| Imig, JD | 1 |
| Červenka, L | 1 |
| Graciano, ML | 1 |
| Mitchell, KD | 1 |
| Rennie, J | 1 |
| Bailey, MA | 1 |
| Bellamy, CO | 1 |
4 other studies available for indole-3-carbinol and Albuminuria
| Article | Year |
|---|---|
Tight blood glycaemic and blood pressure control in experimental diabetic nephropathy reduces extracellular matrix production without regression of fibrosis.
Topics: Albuminuria; Animals; Biomarkers; Blood Glucose; Blood Pressure; Cytochrome P-450 CYP1A1; Diabetes M | 2014 |
Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Topics: 8,11,14-Eicosatrienoic Acid; Albuminuria; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cy | 2016 |
Imatinib ameliorates renal morphological changes in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.
Topics: Albuminuria; Angiotensin II; Animals; Benzamides; Cytochrome P-450 CYP1A1; Hypertension, Malignant; | 2012 |
Hyperglycemia and renin-dependent hypertension synergize to model diabetic nephropathy.
Topics: Albuminuria; Animals; Comorbidity; Cytochrome P-450 CYP1A1; Diabetes Mellitus, Experimental; Diabeti | 2012 |