indole-3-carbinol has been researched along with Adenocarcinoma in 15 studies
indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In earlier studies, we demonstrated the efficacy of indole-3-carbinol (I3C) against lung adenocarcinoma in A/J mice." | 7.77 | Enhanced inhibition of lung adenocarcinoma by combinatorial treatment with indole-3-carbinol and silibinin in A/J mice. ( Dagne, A; Kassie, F; Luo, X; Melkamu, T; Qian, X; Schutten, MM; Upadhyaya, P, 2011) |
| "We studied the chemopreventive efficacy of indole-3-carbinol (I3C), a phytochemical found in cruciferous vegetables, to inhibit tobacco carcinogen-induced lung adenocarcinoma in A/J mice when given following post-initiation or progression protocol." | 7.77 | Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis. ( Kassie, F; Melkamu, T; Qian, X; Upadhyaya, P, 2011) |
| " In this paper, we extended our work and examined the effects of I3C (70 or 30 micromol/g diet) and MI (56 micromol/g diet) against vinyl carbamate (VC)-induced lung adenocarcinoma by administering the agents from 1 week after the second of two injections of VC until termination of the study at week 18." | 7.76 | Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice. ( Hecht, SS; Kalscheuer, S; Kassie, F; Ma, L; Matise, I; Melkamu, T; Upadhyaya, P, 2010) |
| "Human colorectal cancer cell lines DLD1, HCT116, HT-29, LS513, and RKO were treated with indole-3-carbinol or vehicle." | 4.93 | Indole-3-carbinol induces tumor cell death: function follows form. ( Carney, PR; Geiger, P; Kennedy, GD; Megna, BW; Nukaya, M, 2016) |
| "In earlier studies, we demonstrated the efficacy of indole-3-carbinol (I3C) against lung adenocarcinoma in A/J mice." | 3.77 | Enhanced inhibition of lung adenocarcinoma by combinatorial treatment with indole-3-carbinol and silibinin in A/J mice. ( Dagne, A; Kassie, F; Luo, X; Melkamu, T; Qian, X; Schutten, MM; Upadhyaya, P, 2011) |
| "We studied the chemopreventive efficacy of indole-3-carbinol (I3C), a phytochemical found in cruciferous vegetables, to inhibit tobacco carcinogen-induced lung adenocarcinoma in A/J mice when given following post-initiation or progression protocol." | 3.77 | Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis. ( Kassie, F; Melkamu, T; Qian, X; Upadhyaya, P, 2011) |
| " In this paper, we extended our work and examined the effects of I3C (70 or 30 micromol/g diet) and MI (56 micromol/g diet) against vinyl carbamate (VC)-induced lung adenocarcinoma by administering the agents from 1 week after the second of two injections of VC until termination of the study at week 18." | 3.76 | Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice. ( Hecht, SS; Kalscheuer, S; Kassie, F; Ma, L; Matise, I; Melkamu, T; Upadhyaya, P, 2010) |
| "Lung cancer is a prominent cause of cancer-associated mortality worldwide." | 2.52 | Dietary agents for prevention and treatment of lung cancer. ( Khan, N; Mukhtar, H, 2015) |
| "The high incidence of endometrial cancer in this strain of rats might be related to increased estrogen/progesterone ratio with aging." | 1.29 | Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indole-3-carbinol. ( Kojima, T; Mori, H; Tanaka, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, N | 1 |
| Mukhtar, H | 1 |
| Megna, BW | 1 |
| Carney, PR | 1 |
| Nukaya, M | 1 |
| Geiger, P | 1 |
| Kennedy, GD | 1 |
| Kassie, F | 5 |
| Kalscheuer, S | 1 |
| Matise, I | 1 |
| Ma, L | 1 |
| Melkamu, T | 5 |
| Upadhyaya, P | 4 |
| Hecht, SS | 2 |
| Zhang, X | 1 |
| Tan, J | 1 |
| Zeng, Y | 1 |
| Endalew, A | 1 |
| Luo, X | 2 |
| Dagne, A | 1 |
| Schutten, MM | 1 |
| Qian, X | 2 |
| Wu, TY | 1 |
| Saw, CL | 1 |
| Khor, TO | 1 |
| Pung, D | 1 |
| Boyanapalli, SS | 1 |
| Kong, AN | 1 |
| Kang, JK | 1 |
| Yoshida, M | 1 |
| Katashima, S | 1 |
| Ando, J | 1 |
| Tanaka, T | 3 |
| Uematsu, F | 1 |
| Nakae, D | 1 |
| Maekawa, A | 1 |
| Suzui, M | 1 |
| Inamine, M | 1 |
| Kaneshiro, T | 1 |
| Morioka, T | 1 |
| Yoshimi, N | 1 |
| Suzuki, R | 1 |
| Kohno, H | 1 |
| Kojima, T | 1 |
| Mori, H | 1 |
| Kim, DJ | 1 |
| Han, BS | 1 |
| Ahn, B | 1 |
| Hasegawa, R | 1 |
| Shirai, T | 1 |
| Ito, N | 1 |
| Tsuda, H | 1 |
| Staub, RE | 1 |
| Feng, C | 1 |
| Onisko, B | 1 |
| Bailey, GS | 1 |
| Firestone, GL | 1 |
| Bjeldanes, LF | 1 |
| Pence, BC | 1 |
| Buddingh, F | 1 |
| Yang, SP | 1 |
2 reviews available for indole-3-carbinol and Adenocarcinoma
| Article | Year |
|---|---|
Dietary agents for prevention and treatment of lung cancer.
Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phyto | 2015 |
Indole-3-carbinol induces tumor cell death: function follows form.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Bi | 2016 |
13 other studies available for indole-3-carbinol and Adenocarcinoma
| Article | Year |
|---|---|
Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Prol | 2010 |
Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Blotting, Western; Female; Gene Expression Profili | 2010 |
Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Be | 2010 |
Enhanced inhibition of lung adenocarcinoma by combinatorial treatment with indole-3-carbinol and silibinin in A/J mice.
Topics: Adenocarcinoma; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Therapy, Combination; | 2011 |
Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anticarcinogenic Agents; Carcinogens; Cell Growth P | 2011 |
In vivo pharmacodynamics of indole-3-carbinol in the inhibition of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: involvement of Nrf2 and cell cycle/apoptosis signaling pathways.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle; Dietary Supplements; Drug S | 2012 |
Lack of chemoprevention of indole-3-carbinol in N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Dose-Response Relationship, Drug; Eating; Female; | 2002 |
Dietary indole-3-carbinol promotes endometrial adenocarcinoma development in rats initiated with N-ethyl-N'-nitro-N-nitrosoguanidine, with induction of cytochrome P450s in the liver and consequent modulation of estrogen metabolism.
Topics: Adenocarcinoma; Animals; Carcinogens; Cytochrome P-450 Enzyme System; Disease Models, Animal; Endome | 2004 |
Indole-3-carbinol inhibits the growth of human colon carcinoma cells but enhances the tumor multiplicity and volume of azoxymethane-induced rat colon carcinogenesis.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antioxidants; Apoptosis; Cell Cycle; Cell Proliferati | 2005 |
Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indole-3-carbinol.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Diet; Endometrial Neoplasms; Estradiol; Female; Hy | 1994 |
Enhancement by indole-3-carbinol of liver and thyroid gland neoplastic development in a rat medium-term multiorgan carcinogenesis model.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Dieth | 1997 |
Fate of indole-3-carbinol in cultured human breast tumor cells.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Breast Neoplasms; Carbon Isotopes; Carcinoma, Hepa | 2002 |
Multiple dietary factors in the enhancement of dimethylhydrazine carcinogenesis: main effect of indole-3-carbinol.
Topics: Adenocarcinoma; Analysis of Variance; Animal Feed; Animals; Aryl Hydrocarbon Hydroxylases; Body Weig | 1986 |