indium-oxine and Meningitis

111-indium-labelled leukocyte scintigraphy used for testing inflammatory intracranial lesion delimitation in differential diagnosis, shows reliable results in 80% of the cases, whereas 10% demonstrate false-positive as well as false-negative results. Loss of time is caused by the 24 h waiting period for measurement, and because of supply problems. Due to these drawbacks, this method is of only limited help to the neurosurgeon in quickly finding safe pointers for determining the time of operation if inflammatory intracranial lesions are suspected. Hence, this method requires to be improved upon, or a new one should be developed.

Topics: Adult; Aged; Brain Abscess; Female; Humans; Leukocytes; Male; Meningitis; Middle Aged; Organometallic Compounds; Oxyquinoline; Tomography, Emission-Computed, Single-Photon