Page last updated: 2024-08-21

indirubin and Neoplasms

indirubin has been researched along with Neoplasms in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's10 (83.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Hoda, N; Maqbool, M; Mobashir, M1
Evdokimov, NM; Kornienko, A; Magedov, IV; McBrayer, D1
Alam, MS; Hamid, H; Khan, I; Tantray, MA1
Caldon, EC; Tadesse, S; Tilley, W; Wang, S1
Chen, X; Chen, Y; Cui, N; Kong, L; Li, S; Li, X; Luo, H; Luo, Z; Wan, S; Wang, X; Yin, F; Zhang, Y1
Chan, JY; Hoi, PM; Lee, SM; Wang, Y1
Gaboriaud-Kolar, N; Skaltsounis, AL; Vougogiannopoulou, K1
Cheng, X; Merz, KH1
Chakrabarty, K; Hein, M; Karapetyan, G; Langer, P1
Kim, JK; Shin, EK1
Skaltsounis, AL; Vougogiannopoulou, K1
Davies, J; Kibble, A1

Reviews

8 review(s) available for indirubin and Neoplasms

ArticleYear
Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease.
    European journal of medicinal chemistry, 2016, Jan-01, Volume: 107

    Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Diabetes Mellitus; Glycogen Synthase Kinase 3; Hippocampus; Humans; Hypoglycemic Agents; Inflammation; Molecular Targeted Therapy; Neoplasms; Protein Kinase Inhibitors

2016
Natural and synthetic bioactive inhibitors of glycogen synthase kinase.
    European journal of medicinal chemistry, 2017, Jan-05, Volume: 125

    Topics: Alzheimer Disease; Animals; Bipolar Disorder; Clinical Trials as Topic; Diabetes Mellitus; Drug Discovery; Glycogen Synthase Kinase 3; Humans; Models, Molecular; Neoplasms; Patents as Topic; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction

2017
Cyclin-Dependent Kinase 2 Inhibitors in Cancer Therapy: An Update.
    Journal of medicinal chemistry, 2019, 05-09, Volume: 62, Issue:9

    Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Cyclin-Dependent Kinase 2; Drug Design; Humans; Neoplasms; Protein Binding; Protein Conformation; Protein Kinase Inhibitors

2019
New perspective on the dual functions of indirubins in cancer therapy and neuroprotection.
    Anti-cancer agents in medicinal chemistry, 2014, Volume: 14, Issue:9

    Topics: Animals; Antineoplastic Agents; Cyclin-Dependent Kinases; Glycogen Synthase Kinase 3; Humans; Indoles; Neoplasms; Neurodegenerative Diseases; Neuroprotective Agents; Phosphorylation; Protein Kinase Inhibitors; Structure-Activity Relationship

2014
Indirubin derivatives: a patent review (2010 - present).
    Expert opinion on therapeutic patents, 2015, Volume: 25, Issue:5

    Topics: Animals; Antineoplastic Agents; Drug Design; Humans; Indoles; Medicine, Chinese Traditional; Neoplasms; Patents as Topic; Signal Transduction; Solubility

2015
The Role of Indirubins in Inflammation and Associated Tumorigenesis.
    Advances in experimental medicine and biology, 2016, Volume: 929

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Drug Discovery; Drugs, Chinese Herbal; Humans; Indoles; Inflammation; Inflammation Mediators; Medicine, Chinese Traditional; Molecular Structure; Molecular Targeted Therapy; Neoplasms; Phytotherapy; Plants, Medicinal; Protein Kinase Inhibitors; Signal Transduction; Structure-Activity Relationship

2016
Synthesis and bioactivity of carbohydrate derivatives of indigo, its isomers and heteroanalogues.
    ChemMedChem, 2011, Jan-03, Volume: 6, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Female; Glycosides; Glycosylation; Humans; Indigo Carmine; Indoles; Isomerism; Male; Mice; Neoplasms

2011
From Tyrian purple to kinase modulators: naturally halogenated indirubins and synthetic analogues.
    Planta medica, 2012, Volume: 78, Issue:14

    Topics: Animals; Antibiotics, Antineoplastic; Brassicaceae; Fabaceae; Gastropoda; Glycogen Synthase Kinase 3; Halogenation; Heart; Humans; Indoles; Kidney; Leukemia; Neoplasms; Neurodegenerative Diseases; Pancreas; Polygonum; Protein Kinase Inhibitors; Stem Cells; Structure-Activity Relationship

2012

Other Studies

4 other study(ies) available for indirubin and Neoplasms

ArticleYear
Isatin derivatives with activity against apoptosis-resistant cancer cells.
    Bioorganic & medicinal chemistry letters, 2016, Mar-15, Volume: 26, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Isatin; Molecular Structure; Neoplasms; Structure-Activity Relationship

2016
Indirubin derivatives as bifunctional molecules inducing DNA damage and targeting PARP for the treatment of cancer.
    European journal of medicinal chemistry, 2023, Dec-05, Volume: 261

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; DNA Damage; Neoplasms; Phthalazines; Poly(ADP-ribose) Polymerase Inhibitors

2023
Indirubin derivative E804 inhibits angiogenesis.
    BMC cancer, 2012, May-03, Volume: 12

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Movement; Cell Proliferation; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Male; Mice; Microvessels; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Oximes; Rats; Signal Transduction; Tumor Burden; Vascular Endothelial Growth Factor Receptor-2

2012
American Association of Cancer Research--95th annual meeting. Kinases. 27-31 March, 2004, Orlando, FL, USA.
    IDrugs : the investigational drugs journal, 2004, Volume: 7, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Aurora Kinases; Enzyme Inhibitors; Humans; Indoles; Neoplasms; Protein Serine-Threonine Kinases

2004