Page last updated: 2024-08-21

indirubin and Inflammation

indirubin has been researched along with Inflammation in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's9 (81.82)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J1
Hoda, N; Maqbool, M; Mobashir, M1
Guo, F; Guo, J; Guo, Z; Hou, L; Lin, J; Sun, K; Wang, G; Wang, X; Wei, Y; Xu, J; Zhang, X1
Li, H; Li, S; Qi, T1
Deindl, E; Preissner, KT; Weckbach, LT1
Gao, W; Gong, Y; Guo, Y; Lin, Y; Sheng, T; Wang, C; Wu, Z; Yu, L1
Chen, YY; Guo, AZ; Hu, CM; Lai, JL; Liu, C; Liu, RN; Liu, YH; Qi, MP; Zhou, QG; Zhu, XF1
Cheng, X; Merz, KH1
Deng, X; Gao, Q; Gao, X; Gu, L; Wang, Q; Wang, Y; Xiong, X; Ye, B; Zeng, Z1
Hsieh, CC; Huang, JT; Lin, WC; You, WC1
Cho, IH; Choi, YY; Kim, MH; Nam, D; Yang, G; Yang, WM1

Reviews

3 review(s) available for indirubin and Inflammation

ArticleYear
Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease.
    European journal of medicinal chemistry, 2016, Jan-01, Volume: 107

    Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Diabetes Mellitus; Glycogen Synthase Kinase 3; Hippocampus; Humans; Hypoglycemic Agents; Inflammation; Molecular Targeted Therapy; Neoplasms; Protein Kinase Inhibitors

2016
The Role of Midkine in Arteriogenesis, Involving Mechanosensing, Endothelial Cell Proliferation, and Vasodilation.
    International journal of molecular sciences, 2018, Aug-29, Volume: 19, Issue:9

    Topics: Animals; Cell Proliferation; Endothelial Cells; Humans; Indoles; Inflammation; Membrane Glycoproteins; Mice; Midkine; Mutagenesis, Site-Directed; Nitric Oxide Synthase; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Receptors, Growth Factor; Shear Strength; Stress, Mechanical; Vasodilation

2018
The Role of Indirubins in Inflammation and Associated Tumorigenesis.
    Advances in experimental medicine and biology, 2016, Volume: 929

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Drug Discovery; Drugs, Chinese Herbal; Humans; Indoles; Inflammation; Inflammation Mediators; Medicine, Chinese Traditional; Molecular Structure; Molecular Targeted Therapy; Neoplasms; Phytotherapy; Plants, Medicinal; Protein Kinase Inhibitors; Signal Transduction; Structure-Activity Relationship

2016

Other Studies

8 other study(ies) available for indirubin and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature

2010
Indirubin protects chondrocytes and alleviates OA by inhibiting the MAPK and NF-κB pathways.
    International immunopharmacology, 2023, Volume: 115

    Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Chondrocytes; Collagen; Inflammation; Interleukin-1beta; Knee Joint; Mice; Mice, Inbred C57BL; NF-kappa B; Osteoarthritis; Signal Transduction

2023
Indirubin improves antioxidant and anti-inflammatory functions in lipopolysaccharide-challenged mice.
    Oncotarget, 2017, May-30, Volume: 8, Issue:22

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Drug Synergism; Female; Immunoglobulins; Indoles; Inflammation; Lipopolysaccharides; Mice; NF-kappa B; Nitric Oxide Synthase; Oxidative Stress

2017
Indirubin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice through the inhibition of inflammation and the induction of Foxp3-expressing regulatory T cells.
    Acta histochemica, 2016, Volume: 118, Issue:6

    Topics: Animals; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Forkhead Transcription Factors; Indoles; Inflammation; Male; Mice, Inbred BALB C; Signal Transduction; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha

2016
Indirubin Inhibits LPS-Induced Inflammation via TLR4 Abrogation Mediated by the NF-kB and MAPK Signaling Pathways.
    Inflammation, 2017, Volume: 40, Issue:1

    Topics: Animals; Cytokines; Dose-Response Relationship, Drug; Female; Indoles; Inflammation; Inflammation Mediators; Lipopolysaccharides; MAP Kinase Signaling System; Mastitis; Mice; NF-kappa B; Signal Transduction; Toll-Like Receptor 4

2017
Meisoindigo, but not its core chemical structure indirubin, inhibits zebrafish interstitial leukocyte chemotactic migration.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Indoles; Inflammation; Leukocytes; Molecular Structure; Signal Transduction; Structure-Activity Relationship; Time Factors; Zebrafish

2017
Indigowood root extract protects hematopoietic cells, reduces tissue damage and modulates inflammatory cytokines after total-body irradiation: does Indirubin play a role in radioprotection?
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2009, Volume: 16, Issue:12

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Cytokines; Glutamine; Granulocyte Colony-Stimulating Factor; Indoles; Inflammation; Isatis; Leukopenia; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Extracts; Radiation Injuries, Experimental; Radiation-Protective Agents; Random Allocation; Spleen; Thymus Gland

2009
Indirubin, a purple 3,2- bisindole, inhibited allergic contact dermatitis via regulating T helper (Th)-mediated immune system in DNCB-induced model.
    Journal of ethnopharmacology, 2013, Jan-09, Volume: 145, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Disease Models, Animal; Female; Hyperplasia; I-kappa B Proteins; Immune System; Immunoglobulin E; Indoles; Inflammation; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; T-Lymphocytes, Helper-Inducer

2013