indirubin has been researched along with Granulocytic Leukemia, Chronic in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Gaboriaud-Kolar, N; Gerolymatos, P; Horne, DA; Jove, R; Mikros, E; Myrianthopoulos, V; Nam, S; Skaltsounis, AL; Vougogiannopoulou, K | 1 |
| Chen, Y; Long, L; Wang, J; Xu, Y; Zhang, L | 1 |
| Bai, G; Chen, Y; Wang, H; Wang, J; Wang, Z; Wei, C; Xu, Y; Yao, Q; Zhang, L | 1 |
| Chen, F; Hou, M; Ji, C; Li, L; Ma, D; Sun, J; Yan, S; Zhang, M | 1 |
| Bhatia, R; Chen, W; Cheng, X; Eisenbrand, G; Jove, R; Konig, H; Merz, KH; Nam, S; Park, S; Scuto, A; Yang, F; Yoo, HS | 1 |
| Steriti, R | 1 |
| Hao, Y; Liu, B; Qian, L; Xiao, Z | 1 |
| Eisenbrand, G; Hippe, F; Jakobs, S; Muehlbeyer, S | 1 |
4 review(s) available for indirubin and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Anticancer potential of indirubins in medicinal chemistry: Biological activity, structural modification, and structure-activity relationship.
Topics: Antineoplastic Agents; Cell Survival; Chemistry, Pharmaceutical; Drugs, Chinese Herbal; Humans; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Oximes; Structure-Activity Relationship | 2021 |
Nutritional support for chronic myelogenous and other leukemias: a review of the scientific literature.
Topics: Antineoplastic Agents; Curcumin; Humans; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Nutritional Support; Tretinoin; Vitamins | 2002 |
Indirubin and meisoindigo in the treatment of chronic myelogenous leukemia in China.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Blast Crisis; China; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Models, Chemical; Time Factors; Treatment Outcome | 2002 |
Molecular mechanisms of indirubin and its derivatives: novel anticancer molecules with their origin in traditional Chinese phytomedicine.
Topics: Adenosine Triphosphate; Alzheimer Disease; Antibiotics, Antineoplastic; Cell Cycle; Cyclin-Dependent Kinases; Diabetes Mellitus; Enzyme Inhibitors; Humans; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Medicine, Chinese Traditional; Structure-Activity Relationship | 2004 |
4 other study(ies) available for indirubin and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Natural-Based Indirubins Display Potent Cytotoxicity toward Wild-Type and T315I-Resistant Leukemia Cell Lines.
Topics: Apoptosis; Benzamides; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; CSK Tyrosine-Protein Kinase; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Structure; Piperazines; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases | 2016 |
Design, synthesis and antineoplastic activity of novel hybrids of podophyllotoxin and indirubin against human leukaemia cancer cells as multifunctional anti-MDR agents.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Down-Regulation; Drug Design; Drug Resistance, Neoplasm; G2 Phase Cell Cycle Checkpoints; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Dynamics Simulation; Multidrug Resistance-Associated Proteins; Podophyllotoxin; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Signal Transduction; Tubulin | 2018 |
Imatinib achieved complete cytogenetic response in a CML patient received 32-year indirubin and its derivative treatment.
Topics: Adult; Benzamides; Cytogenetic Analysis; Humans; Imatinib Mesylate; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Neoplasm, Residual; Philadelphia Chromosome; Piperazines; Pyrimidines; Remission Induction | 2010 |
Indirubin derivatives induce apoptosis of chronic myelogenous leukemia cells involving inhibition of Stat5 signaling.
Topics: Apoptosis; Benzamides; Blotting, Western; Cell Line, Tumor; Cell Survival; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Humans; Imatinib Mesylate; Immunoprecipitation; Indoles; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Oximes; Piperazines; Pyridones; Pyrimidines; Signal Transduction; STAT5 Transcription Factor | 2012 |