indirubin has been researched along with Disease Models, Animal in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 4 (30.77) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Lai, XY; Li, MS; Liu, B; Liu, XM; Long, MY; Wang, JD; Xu, CL; Yu, GM; Zhou, LF; Zhu, YM | 1 |
| Han, L; Huang, S; Lin, J; Liu, J; Tian, S; Xie, J; Xu, R; Yang, M; Yang, X; Zhang, D | 1 |
| Cao, R; Han, L; Huang, Q; Lin, J; Liu, J; Tian, S; Xie, H; Xie, J; Yang, M; Zhang, D | 1 |
| Li, H; Li, S; Qi, T | 1 |
| Dai, H; Hu, J; Li, C; Li, J; Tao, C; Wu, J; Xu, J; Xue, X | 1 |
| Bastos, TM; Efstathiou, A; Gaboriaud-Kolar, N; Meira, CS; Rocha, VPC; Skaltsounis, AL; Smirlis, D; Soares, MBP; Vougogiannopoulou, K | 1 |
| Ju, X; Ning, B; Sun, N; Wei, J; Zhang, A | 1 |
| Gao, W; Gong, Y; Guo, Y; Lin, Y; Sheng, T; Wang, C; Wu, Z; Yu, L | 1 |
| Deng, X; Gao, Q; Gao, X; Gu, L; Wang, Q; Wang, Y; Xiong, X; Ye, B; Zeng, Z | 1 |
| Alex, D; Lam, IK; Lee, SM; Lin, Z | 1 |
| Cho, IH; Choi, YY; Kim, MH; Nam, D; Yang, G; Yang, WM | 1 |
| Ahn, SG; Kim, SA; Kim, SW; Kim, YC; Lee, SH; Min, JJ; Yoon, JH | 1 |
13 other study(ies) available for indirubin and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Therapeutic effect of indirubin-loaded bovine serum albumin nanoparticules on ulcerative colitis.
Topics: Animals; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Humans; Indoles; Mice; Mice, Inbred BALB C; Serum Albumin, Bovine | 2022 |
Combination Therapy with Indigo and Indirubin for Ulcerative Colitis via Reinforcing Intestinal Barrier Function.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Indigo Carmine; Mice; Reactive Oxygen Species | 2023 |
Hyaluronic acid/inulin-based nanocrystals with an optimized ratio of indigo and indirubin for combined ulcerative colitis therapy via immune and intestinal flora regulation.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Hyaluronic Acid; Indigo Carmine; Inulin; Mice; Mice, Inbred C57BL; Nanoparticles | 2023 |
Indirubin improves antioxidant and anti-inflammatory functions in lipopolysaccharide-challenged mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Drug Synergism; Female; Immunoglobulins; Indoles; Inflammation; Lipopolysaccharides; Mice; NF-kappa B; Nitric Oxide Synthase; Oxidative Stress | 2017 |
Indirubin attenuates mouse psoriasis-like skin lesion in a CD274-dependent manner: an achievement of RNA sequencing.
Topics: Adolescent; Adult; Aged; Animals; B7-H1 Antigen; CDC2 Protein Kinase; Disease Models, Animal; Epidermis; Female; Flow Cytometry; Gene Expression Regulation; Humans; Indoles; Interferon-gamma; Interleukin-17; Keratinocytes; Male; Mice; Middle Aged; Primary Cell Culture; Psoriasis; Sequence Analysis, RNA; Skin Abnormalities; Toll-Like Receptor 3; Toll-Like Receptor 4; Young Adult | 2018 |
Indirubin derivatives are potent and selective anti-Trypanosoma cruzi agents.
Topics: Animals; Chagas Disease; Disease Models, Animal; Female; Flow Cytometry; Indoles; Mice; Mice, Inbred BALB C; Nitroimidazoles; Parasitemia; Trypanocidal Agents; Trypanosoma cruzi | 2018 |
Indirubin Increases CD4+CD25+Foxp3+ Regulatory T Cells to Prevent Immune Thrombocytopenia in Mice.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Blood Platelets; Disease Models, Animal; Female; Flow Cytometry; Forkhead Transcription Factors; Immune Tolerance; Immunosuppressive Agents; Indoles; Interleukin-2 Receptor alpha Subunit; Lymph Nodes; Mice; Mice, Inbred CBA; Microscopy, Fluorescence; Purpura, Thrombocytopenic, Idiopathic; Rats; Rats, Wistar; Spleen; T-Lymphocytes, Regulatory | 2015 |
Indirubin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice through the inhibition of inflammation and the induction of Foxp3-expressing regulatory T cells.
Topics: Animals; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Forkhead Transcription Factors; Indoles; Inflammation; Male; Mice, Inbred BALB C; Signal Transduction; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha | 2016 |
Meisoindigo, but not its core chemical structure indirubin, inhibits zebrafish interstitial leukocyte chemotactic migration.
Topics: Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Indoles; Inflammation; Leukocytes; Molecular Structure; Signal Transduction; Structure-Activity Relationship; Time Factors; Zebrafish | 2017 |
Indirubin shows anti-angiogenic activity in an in vivo zebrafish model and an in vitro HUVEC model.
Topics: Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Apoptosis; Cell Cycle; Cell Line; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Endothelium, Vascular; Humans; In Situ Nick-End Labeling; Indoles; Magnoliopsida; Umbilical Veins; Zebrafish | 2010 |
Indirubin, a purple 3,2- bisindole, inhibited allergic contact dermatitis via regulating T helper (Th)-mediated immune system in DNCB-induced model.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dermatitis, Allergic Contact; Dinitrochlorobenzene; Disease Models, Animal; Female; Hyperplasia; I-kappa B Proteins; Immune System; Immunoglobulin E; Indoles; Inflammation; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; T-Lymphocytes, Helper-Inducer | 2013 |
Antitumor activity of novel indirubin derivatives in rat tumor model.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Disease Models, Animal; Drug Screening Assays, Antitumor; Humans; Indoles; Inhibitory Concentration 50; Male; Neoplasm Transplantation; Rats; Rats, Sprague-Dawley | 2007 |