Page last updated: 2024-08-21

indirubin and Alzheimer Disease

indirubin has been researched along with Alzheimer Disease in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Hoda, N; Maqbool, M; Mobashir, M1
Alam, MS; Hamid, H; Khan, I; Tantray, MA1
Ahmad, SS; Almalki, AS; Khalid, M; Khan, H1
Dubbs, JM; Loprasert, S; Mongkolsuk, S; Sallabhan, R; Wongsaroj, L1
Eisenbrand, G; Hippe, F; Jakobs, S; Muehlbeyer, S1
Bibb, JA; Biernat, J; Eisenbrand, G; Garnier, M; Greengard, P; Hoessel, R; Leclerc, S; Mandelkow, EM; Marko, D; Meijer, L; Snyder, GL; Wu, YZ1

Reviews

3 review(s) available for indirubin and Alzheimer Disease

ArticleYear
Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease.
    European journal of medicinal chemistry, 2016, Jan-01, Volume: 107

    Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Diabetes Mellitus; Glycogen Synthase Kinase 3; Hippocampus; Humans; Hypoglycemic Agents; Inflammation; Molecular Targeted Therapy; Neoplasms; Protein Kinase Inhibitors

2016
Natural and synthetic bioactive inhibitors of glycogen synthase kinase.
    European journal of medicinal chemistry, 2017, Jan-05, Volume: 125

    Topics: Alzheimer Disease; Animals; Bipolar Disorder; Clinical Trials as Topic; Diabetes Mellitus; Drug Discovery; Glycogen Synthase Kinase 3; Humans; Models, Molecular; Neoplasms; Patents as Topic; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction

2017
Molecular mechanisms of indirubin and its derivatives: novel anticancer molecules with their origin in traditional Chinese phytomedicine.
    Journal of cancer research and clinical oncology, 2004, Volume: 130, Issue:11

    Topics: Adenosine Triphosphate; Alzheimer Disease; Antibiotics, Antineoplastic; Cell Cycle; Cyclin-Dependent Kinases; Diabetes Mellitus; Enzyme Inhibitors; Humans; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Medicine, Chinese Traditional; Structure-Activity Relationship

2004

Other Studies

3 other study(ies) available for indirubin and Alzheimer Disease

ArticleYear
Emetine and Indirubin- 3- monoxime interaction with human brain acetylcholinesterase: A computational and statistical analysis.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Jan-02, Volume: 67, Issue:4

    Topics: Acetylcholinesterase; Alzheimer Disease; Binding Sites; Brain; Catalytic Domain; Cholinesterase Inhibitors; Emetine; Humans; Indoles; Ligands; Molecular Docking Simulation

2022
Cloning of Toluene 4-Monooxygenase Genes and Application of Two-Phase System to the Production of the Anticancer Agent, Indirubin.
    Molecular biotechnology, 2015, Volume: 57, Issue:8

    Topics: Alzheimer Disease; Antibiotics, Antineoplastic; Bacterial Proteins; Cloning, Molecular; Escherichia coli; Humans; Indoles; Leukemia, Myeloid; Oxygenases; Pseudomonas

2015
Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?
    The Journal of biological chemistry, 2001, Jan-05, Volume: 276, Issue:1

    Topics: Adenosine Triphosphate; Alkaloids; Alzheimer Disease; Animals; Antibiotics, Antineoplastic; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Cyclin B; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Indoles; Inhibitory Concentration 50; Mice; Molecular Structure; Neostriatum; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Phosphothreonine; Piperidines; Staurosporine; tau Proteins

2001