indirubin-3'-monoxime has been researched along with Parkinson Disease in 2 studies
indirubin-3'-monoxime: has antiangiogenic activity
indirubin-3'-monoxime : A member of the class of biindoles that is indirubin in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Doggrell, SA | 1 |
| Castelo-Branco, G | 1 |
| Rawal, N | 1 |
| Arenas, E | 1 |
2 other studies available for indirubin-3'-monoxime and Parkinson Disease
| Article | Year |
|---|---|
A new approach to Parkinson's disease: inhibition of leucine-rich repeat kinase-2.
Topics: Animals; Antiparkinson Agents; Cell Culture Techniques; Cell Death; Corpus Striatum; Genetic Vectors | 2011 |
GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons.
Topics: Animals; Benzazepines; beta Catenin; Brain; Cell Differentiation; Cell Proliferation; Cell Survival; | 2004 |