indirubin-3'-monoxime has been researched along with Obesity in 3 studies
indirubin-3'-monoxime: has antiangiogenic activity
indirubin-3'-monoxime : A member of the class of biindoles that is indirubin in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Obesity is a growing issue of the modern world, and its negative impact on bones in obese male patients has been recently reported." | 1.40 | Indirubin-3'-oxime, an activator of Wnt/β-catenin signaling, enhances osteogenic commitment of ST2 cells and restores bone loss in high-fat diet-induced obese male mice. ( Cha, PH; Choi, KY; Zahoor, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, C | 1 |
| Qi, L | 1 |
| Xue, J | 1 |
| Wang, Y | 1 |
| Choi, OM | 1 |
| Cho, YH | 1 |
| Choi, S | 1 |
| Lee, SH | 1 |
| Seo, SH | 1 |
| Kim, HY | 1 |
| Han, G | 1 |
| Min, DS | 1 |
| Park, T | 1 |
| Choi, KY | 2 |
| Zahoor, M | 1 |
| Cha, PH | 1 |
3 other studies available for indirubin-3'-monoxime and Obesity
| Article | Year |
|---|---|
Indirubin-3'-oxime promotes the efficacy of GnRHa in obese-induced central precocious puberty and maintains normal bone growth and body weight via the ERK-Sp1-KISS-1/GPR54 axis.
Topics: Animals; Body Weight; Bone Development; Female; Kisspeptins; Mice; Mice, Inbred C57BL; Obesity; Oxim | 2023 |
The small molecule indirubin-3'-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Cell Differentiation; Diet, Hi | 2014 |
Indirubin-3'-oxime, an activator of Wnt/β-catenin signaling, enhances osteogenic commitment of ST2 cells and restores bone loss in high-fat diet-induced obese male mice.
Topics: Adipogenesis; Animals; beta Catenin; Cell Line; Diet, High-Fat; Gene Expression; Indoles; Male; Mice | 2014 |