indirubin-3'-monoxime has been researched along with Disease Models, Animal in 8 studies
indirubin-3'-monoxime: has antiangiogenic activity
indirubin-3'-monoxime : A member of the class of biindoles that is indirubin in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using an oral cancer mouse model, we demonstrate that topical application of an adhesive gel composed of I3M and poly(vinyl alcohol) (I3M/PVA) has dose-dependent anti-tumorigenic effects." | 1.39 | An indirubin derivative, indirubin-3'-monoxime suppresses oral cancer tumorigenesis through the downregulation of survivin. ( Chang, NW; Lo, WY, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 2 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Dera, AA | 1 |
| Rajagopalan, P | 1 |
| Al Fayi, M | 1 |
| Ahmed, I | 1 |
| Chandramoorthy, HC | 1 |
| Sathiya Priya, C | 1 |
| Vidhya, R | 1 |
| Kalpana, K | 1 |
| Anuradha, CV | 1 |
| Lo, WY | 1 |
| Chang, NW | 1 |
| Ding, Y | 1 |
| Qiao, A | 1 |
| Fan, GH | 1 |
| Schwaiberger, AV | 1 |
| Heiss, EH | 1 |
| Cabaravdic, M | 1 |
| Oberan, T | 1 |
| Zaujec, J | 1 |
| Schachner, D | 1 |
| Uhrin, P | 1 |
| Atanasov, AG | 1 |
| Breuss, JM | 1 |
| Binder, BR | 1 |
| Dirsch, VM | 1 |
| Wang, W | 1 |
| Yang, Y | 1 |
| Ying, C | 1 |
| Ruan, H | 1 |
| Zhu, X | 1 |
| You, Y | 1 |
| Han, Y | 1 |
| Chen, R | 1 |
| Wang, Y | 1 |
| Li, M | 1 |
8 other studies available for indirubin-3'-monoxime and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Indirubin-3-monoxime and thymoquinone exhibit synergistic efficacy as therapeutic combination in in-vitro and in-vivo models of Lung cancer.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Cell Cycle; Cell Line; Cell Pr | 2020 |
Indirubin-3'-monoxime prevents aberrant activation of GSK-3β/NF-κB and alleviates high fat-high fructose induced Aβ-aggregation, gliosis and apoptosis in mice brain.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Brain; Diet, High-Fat; Disease Models, Animal; Fructose; | 2019 |
An indirubin derivative, indirubin-3'-monoxime suppresses oral cancer tumorigenesis through the downregulation of survivin.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; | 2013 |
Indirubin-3'-monoxime rescues spatial memory deficits and attenuates beta-amyloid-associated neuropathology in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Anim | 2010 |
Indirubin-3'-monoxime blocks vascular smooth muscle cell proliferation by inhibition of signal transducer and activator of transcription 3 signaling and reduces neointima formation in vivo.
Topics: Animals; Arterial Occlusive Diseases; Becaplermin; Cell Cycle; Cell Proliferation; Cells, Cultured; | 2010 |
Inhibition of glycogen synthase kinase-3beta protects dopaminergic neurons from MPTP toxicity.
Topics: Analysis of Variance; Animals; Apoptosis; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Re | 2007 |