indinavir-sulfate and Acidosis--Lactic

indinavir-sulfate has been researched along with Acidosis--Lactic* in 3 studies

Reviews

1 review(s) available for indinavir-sulfate and Acidosis--Lactic

Article	Year
[Antiretrovirals]. Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 2 Topics: Acidosis, Lactic; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Hemophilia A; Hemorrhage; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Indinavir; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine	2003

Other Studies

2 other study(ies) available for indinavir-sulfate and Acidosis--Lactic

Article	Year
Type B lactic acidosis: a rare complication of antiretroviral therapy after cardiac surgery. The Annals of thoracic surgery, 2002, Volume: 74, Issue:4 This report describes a 47-year-old woman with human immunodeficiency virus (HIV) and end-stage renal disease on hemodialysis, treated with combination antiretroviral drug therapy, who developed an acute, severe type B lactic acidosis 24 hours after homograft root replacement for endocarditis. She fully recovered after HIV medication was discontinued, along with administration of riboflavin and supportive measures including hemodialysis. The timing of this complication and previous reports suggest that open heart surgery may be a risk factor for nonischemic (type B) lactic acidosis in patients taking nucleoside analogue reverse transcriptase inhibitors. Topics: Acidosis, Lactic; Anti-HIV Agents; Aortic Valve; Female; Heart Valve Prosthesis; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Kidney Failure, Chronic; Lamivudine; Middle Aged; Postoperative Complications; Renal Dialysis; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine	2002
[Fatal lactic acidosis in a patient with acquired immunodeficiency syndrome treated with stavudine, lamivudine and indinavir]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1999, Volume: 73, Issue:12 Recently, several class-related adverse events have been recognized with antiretroviral drugs. For nucleoside analogue reverse transcriptase inhibitors. (NRTI), lactic acidosis with hepatomegaly and hepatic steatosis have been reported. These appear to occur at a low frequency, but with a high fatality rate. We report a case of fatal lactic acidosis in a patient with acquired immunodeficiency syndrome (AIDS) treated with stavudine (d4T), lamivudine (3TC) and indinavir (IDV). A 48-year-old male AIDS patient was admitted with complaints of general fatigue and dyspnea. His medications at presentation included d4T, 3TC and IDV. Physical examination demonstrated icteric sclerae and abdominal tenderness with hepatomegaly. Laboratory data demonstrated a severe metabolic acidosis with an anion gap due to lactate accumulation. Despite intensive treatment, cardiorespiratory arrest occurred and this could not be resuscitated. Topics: Acidosis, Lactic; Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; Fatal Outcome; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine	1999

Article

Year

Type B lactic acidosis: a rare complication of antiretroviral therapy after cardiac surgery.

The Annals of thoracic surgery, 2002, Volume: 74, Issue:4

This report describes a 47-year-old woman with human immunodeficiency virus (HIV) and end-stage renal disease on hemodialysis, treated with combination antiretroviral drug therapy, who developed an acute, severe type B lactic acidosis 24 hours after homograft root replacement for endocarditis. She fully recovered after HIV medication was discontinued, along with administration of riboflavin and supportive measures including hemodialysis. The timing of this complication and previous reports suggest that open heart surgery may be a risk factor for nonischemic (type B) lactic acidosis in patients taking nucleoside analogue reverse transcriptase inhibitors.

Topics: Acidosis, Lactic; Anti-HIV Agents; Aortic Valve; Female; Heart Valve Prosthesis; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Kidney Failure, Chronic; Lamivudine; Middle Aged; Postoperative Complications; Renal Dialysis; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine

2002

[Fatal lactic acidosis in a patient with acquired immunodeficiency syndrome treated with stavudine, lamivudine and indinavir].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1999, Volume: 73, Issue:12

Recently, several class-related adverse events have been recognized with antiretroviral drugs. For nucleoside analogue reverse transcriptase inhibitors. (NRTI), lactic acidosis with hepatomegaly and hepatic steatosis have been reported. These appear to occur at a low frequency, but with a high fatality rate. We report a case of fatal lactic acidosis in a patient with acquired immunodeficiency syndrome (AIDS) treated with stavudine (d4T), lamivudine (3TC) and indinavir (IDV). A 48-year-old male AIDS patient was admitted with complaints of general fatigue and dyspnea. His medications at presentation included d4T, 3TC and IDV. Physical examination demonstrated icteric sclerae and abdominal tenderness with hepatomegaly. Laboratory data demonstrated a severe metabolic acidosis with an anion gap due to lactate accumulation. Despite intensive treatment, cardiorespiratory arrest occurred and this could not be resuscitated.

Topics: Acidosis, Lactic; Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; Fatal Outcome; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine

1999