indigo-carmine and Peritonitis

In the experiment on mongrel dogs, the absorption of indigo carmine dye after its retroperitoneal administration with 10% dimexide solution into the lymphatic and venous systems was studied. More rapid delivery of a dye into the portal system, including the cases with portal hypertension, and into the lymphatic system was established. A method for retroperitoneal administration of antibiotics with 10% dimexide solution for prevention and treatment of purulent-septic complications in patients with acute appendicitis has been developed. The method was used in 120 patients, the result of treatment is good.

Topics: Acute Disease; Animals; Anti-Bacterial Agents; Appendicitis; Combined Modality Therapy; Dimethyl Sulfoxide; Dogs; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Hypertension, Portal; Indigo Carmine; Kanamycin; Peritonitis; Sepsis