indigo-carmine and Nasopharyngeal-Neoplasms

To follow up the chronological change of tubal function in patients with nasopharyngeal carcinoma for 10 years after irradiation.. Patients with nasopharyngeal carcinoma were subjected to eustachian tube function tests before irradiation and 6 months, 5 years, and 10 years after irradiation.. University hospital.. Ten patients (20 ears), 7 men and 3 women.. Twelve (60%) of the ears had patulous tubes 10 years after irradiation, which might result from atrophy of peritubal tissues. The occurrence of a patulous tube was independent of the radiation dosage, but it was related to the interval since irradiation.. Development of a patulous tube is associated with correction of organic obstruction of the eustachian tube. Resolution of the inflammatory reaction plays the most important role in recovery of function of the tube. Therefore, the prevalence of middle ear complications is low 10 years after irradiation.

Topics: Adult; Aged; Atrophy; Carcinoma; Coloring Agents; Eustachian Tube; Female; Follow-Up Studies; Humans; Indigo Carmine; Longitudinal Studies; Male; Middle Aged; Nasopharyngeal Neoplasms; Otitis Media; Otitis Media with Effusion; Pressure; Prevalence; Radiotherapy Dosage; Time Factors