indigo-carmine and Infertility--Female

To evaluate whether the presence of a visualizable "flow" effect in the fallopian tube ostia in hysteroscopy was predictive of tubal patency.. A prospective cohort study.. In a prospective study, infertile women who underwent surgery because of infertility between March and November 2018 were included. The main outcome parameter was fallopian tube patency assessed by laparoscopic chromopertubation. The predictive parameter tested was the presence of hysteroscopic tube flow.. Seventy-two infertile women.. Combined hysteroscopy and laparoscopy with chromopertubation.. One-hundred forty-four fallopian tubes were evaluated, with 88 (61.1%) patent tubes at laparoscopic chromopertubation. A positive hysteroscopic flow effect was recorded for 94 (65.3%) ostia and was accurate in predicting patency (p < .001), with a sensitivity of 85.3% (95% confidence interval [CI], 76.1-91.9) and a specificity of 66.1% (95% CI, 52.2-78.2). A multivariate binary regression model revealed that the presence of a hydrosalpinx (odds ratio = 8.216; 95% CI, 1.062-63.574; p = .044) and peritubal adhesions (odds ratio = 3.439; 95% CI, 1.142-10.353; p = .028) were associated with a false-normal flow result. A hazy hysteroscopic picture was found in 15 of 21 (71.4%) and 5 of 51 (9.8%) cases with and without bilateral tubal occlusion, respectively (p < .001, sensitivity = 71.4% [95% CI, 47.8-88.7], specificity = 90.2% [95% CI, 78.6-96.7]).. The presence of hysteroscopic tubal flow was a reliable indicator of tubal patency. A hydrosalpinx or peritubal adhesions increase the risk for a false-normal result. A hazy hysteroscopic picture suggests bilateral tubal occlusion. Using the hysteroscopic flow effect, one can provide additional information for the patient.

Topics: Adolescent; Adult; Fallopian Tube Diseases; Fallopian Tube Patency Tests; Female; Humans; Hysteroscopy; Indigo Carmine; Infertility, Female; Laparoscopy; Middle Aged; Predictive Value of Tests; Prospective Studies; Sensitivity and Specificity; Staining and Labeling; Young Adult

Diagnostic techniques for oviductal obstruction in the mare are limited and development of a more reliable and direct method to assess oviductal patency is needed.. To evaluate the feasibility of hysteroscopic selective hydrotubation of the equine oviduct via videoendoscopy in standing mares.. Using a catheter inserted under endoscopic guidance into the uterotubal junctions of 10 mares, 5 ml of indigo carmine solution (4 mg/ml) was flushed into the oviduct. After introduction of the dye, peritoneal fluid was obtained via abdominocentesis. A colpotomy was also performed to allow introduction of a videoendoscope into the abdominal cavity to assess the presence of dye visually at the ovarian end of the oviduct.. In 15 of 20 (75.0%) attempts, the catheter was successfully inserted into the uterotubal junction, and dye was observed at the ampulla, fimbria, overlying the ovary or surrounding tissue. In 2 mares, the videoendoscope could not be manipulated to identify the uterotubal junction. Only one of 2 oviducts was flushed in an additional mare because insufflation of the uterus could not be maintained. The colour of the dye was evident macroscopically and spectrophotometrically in 4 of 8 mares from which peritoneal fluid was successfully collected.. The equine oviduct can be evaluated by hysteroscopic selective hydrotubation.

Topics: Animals; Fallopian Tube Diseases; Fallopian Tube Patency Tests; Female; Horse Diseases; Horses; Indigo Carmine; Infertility, Female

To report the technique and outcome of laparoscopy in endometriosis using indigo carmine.. Case report.. Tertiary care center.. Twenty-nine-year-old nulligravid woman with a history of endometriosis and left unicornuate uterus with an absent right horn with a present right ovary and distal fallopian tube with recurrence of disease.. Operative laparoscopy for destruction of endometriosis and chromopertubation, given the patient's history of infertility.. Identification of endometriosis.. Lesions of endometriosis were stained with indigo carmine and were easily identified.. Tissue staining demonstrated lesions of endometriosis that were more easily identified; therefore, this technique could provide a special and unique approach to a more accurate diagnosis of endometriosis.

Topics: Adult; Coloring Agents; Endometriosis; Female; Humans; Indigo Carmine; Infertility, Female; Laparoscopy; Reproducibility of Results

Topics: Fallopian Tubes; Female; Humans; Indigo Carmine; Indoles; Infertility, Female; Laparoscopy; Pregnancy