indicine-n-oxide and Liver-Diseases

indicine-n-oxide has been researched along with Liver-Diseases* in 1 studies

Other Studies

1 other study(ies) available for indicine-n-oxide and Liver-Diseases

Article	Year
Hepatic failure secondary to indicine N-oxide toxicity. A Pediatric Oncology Group Study. Cancer, 1983, Jul-01, Volume: 52, Issue:1 Indicine N-oxide, a pyrrolizidine alkaloid, was given to a five-year-old boy with refractory acute myelocytic leukemia. Three days after receiving the drug the patient developed signs and symptoms of acute hepatic failure. The patient died nine days after receiving the drug and an autopsy showed massive hepatic necrosis. The acute hepatic failure observed in this patient may have been secondary to indicine N-oxide toxicity. Topics: Antineoplastic Agents, Phytogenic; Chemical and Drug Induced Liver Injury; Child, Preschool; Humans; Leukemia, Myeloid, Acute; Liver Diseases; Male; Pyrrolizidine Alkaloids	1983

Article

Year

Hepatic failure secondary to indicine N-oxide toxicity. A Pediatric Oncology Group Study.

Cancer, 1983, Jul-01, Volume: 52, Issue:1

Indicine N-oxide, a pyrrolizidine alkaloid, was given to a five-year-old boy with refractory acute myelocytic leukemia. Three days after receiving the drug the patient developed signs and symptoms of acute hepatic failure. The patient died nine days after receiving the drug and an autopsy showed massive hepatic necrosis. The acute hepatic failure observed in this patient may have been secondary to indicine N-oxide toxicity.

Topics: Antineoplastic Agents, Phytogenic; Chemical and Drug Induced Liver Injury; Child, Preschool; Humans; Leukemia, Myeloid, Acute; Liver Diseases; Male; Pyrrolizidine Alkaloids

1983