indican has been researched along with Kidney Failure, Chronic in 120 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (3.33) | 18.7374 |
1990's | 5 (4.17) | 18.2507 |
2000's | 24 (20.00) | 29.6817 |
2010's | 68 (56.67) | 24.3611 |
2020's | 19 (15.83) | 2.80 |
Authors | Studies |
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Asaba, H; Deguchi, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T | 1 |
Carlier, A; Giselbrecht, S; King, J; Masereeuw, R; Swapnasrita, S; Truckenmüller, R | 1 |
Guo, X; He, S; Li, L; Liang, W; Lin, X; Wang, H; Xiang, S; Xiong, Q; Yao, Y; Ying, C; Zhang, P; Zhao, J; Zuo, X | 1 |
Chuang, VTG; Hirata, K; Ikeda, T; Maruyama, T; Nishi, K; Otagiri, M; Sakurama, K; Tanaka, M; Uchida, Y; Watanabe, H; Yamasaki, K | 1 |
Han, L; Jia, L; Li, J; Li, L; Liu, S; Mei, F; Shan, J; Xiao, J; Zhou, J | 1 |
Chen, X; Chen, Z; Guo, Z; Hu, J; Kong, F; Xie, N | 1 |
Hendriks, FK; Kooman, JP; Kuijpers, JHW; Meex, SJR; Senden, JMG; van der Sande, FM; van Kranenburg, JMX; van Loon, LJC | 1 |
Asgharian, M; Ghojazadeh, M; Gholizadeh, P; Jouyban, A; Samadi Kafil, H; Samadi, A; Soleymani, J; Tayebi Khosroshahi, H | 1 |
Adoberg, A; Arund, J; Dhondt, A; Fridolin, I; Glorieux, G; Holmar, J; Lauri, K; Leis, L; Luman, M; Paats, J; Pilt, K; Tanner, R; Uhlin, F | 1 |
Chen, Z; Gao, S; Luo, X; Mao, Z; Xing, X; Xu, J; Xue, C | 1 |
Abate, M; Capasso, A; Capasso, G; Caraglia, M; De, A; Di Paola, R; Izhar, R; La Russa, A; Perna, AF; Simeoni, M; Zappavigna, S | 1 |
Chang, L; Guo, Z; He, L; Li, Y; Tian, R; Xu, Y; Zhang, H | 1 |
Arvizu-Hernández, M; Caballero-Islas, AE; Camacho-Colin, D; Correa-Rotter, R; Del Toro-Cisneros, N; Gómez-Correa, LL; Hernandez-Ordoñez, SÓ; Martínez-Rueda, A; Vega-Vega, O | 1 |
Hillmer, H; Krause, S; Marcelli, D; Meibaum, J; Strohhöfer, C | 1 |
Adoberg, A; Arduan Ortiz, A; Arund, J; Dhondt, A; Fernström, A; Fridolin, I; Glorieux, G; Gonzalez-Parra, E; Leis, L; Luman, M; Paats, J; Perez-Gomez, VM; Pilt, K; Sanchez-Ospina, D; Segelmark, M; Uhlin, F | 1 |
Cheng, BC; Huang, CC; Lai, YR; Lu, CH | 1 |
Choi, HY; Han, SW; Jhee, JH; Jo, YI; Kim, SH; Lee, SH; Lee, SY; Park, HC; Shin, SK; Yang, DH; Yi, JH | 1 |
Hwang, Y; Kim, HC; Kim, HY; Lee, GH; Lee, SJ; Lee, WW; Yoo, TH; Yoon, CE | 1 |
Chou, HH; Huang, HL; Hung, SC; Lin, TY | 1 |
Giebułtowicz, J; Korytowska, N; Pączek, L; Wyczałkowska-Tomasik, A | 1 |
Blaser, MJ; Gao, Z; Holzman, R; Jhawar, S; Liebes, L; Lowenstein, J; Matalon, A; Nazzal, L; Roberts, J; Singh, P | 1 |
Cho, JY; Hwang, Y; Jang, J; Kim, B; Kim, HC; Kim, HY; Kim, MC; Lee, CJ; Lee, GH; Lee, WW; Park, S; Yoo, TH; Yu, HT | 1 |
Ei, I; Gejyo, F; Goto, S; Iguchi, A; Kaneko, Y; Kazama, JJ; Narita, I; Omori, K; Sato, M; Sato, Y; Suzuki, Y; Takahashi, Y; Wakamatsu, T; Yamamoto, S | 1 |
Banerjee, T; Coresh, J; Hostetter, TH; Hwang, S; Melamed, ML; Meyer, TW; Plummer, NS; Powe, NR; Shafi, T; Sirich, TL | 1 |
Chen, J; Ding, X; Gu, Y; Hu, J; Shen, Z; Xu, L; Zhang, H; Zhang, X | 1 |
Abe, T; Ito, S; Kisu, K; Matsumoto, Y; Mishima, E; Miura, D; Mori, T; Morikawa-Ichinose, T; Niwa, T; Oe, Y; Saigusa, D; Saito, R; Sato, E; Sato, H; Sekimoto, A; Takahashi, N; Tomioka, Y; Uchida, T | 1 |
Atherton, JG; Bissler, J; Hains, DS; Lindner, E; Pendley, BD | 1 |
Chen, S; Chen, X; Gao, S; Mao, Z; Mei, C; Pan, X; Ruan, M; Xing, X; Xu, J | 1 |
Ando, Y; Ishida, H; Ito, K; Kurabayashi, M; Kurosawa, K; Negishi, K; Obokata, M; Ogawa, T | 1 |
Ding, F; Li, Y; Liu, T; Ma, S; Shi, Y; Tian, H; Wang, W; Wang, Y; Zhu, Q | 1 |
Guo, CC; Xia, WW; Zhang, AH | 1 |
Coresh, J; Hostetter, TH; Melamed, ML; Meyer, TW; Parekh, R; Plantinga, L; Powe, NR; Shafi, T | 1 |
Abe, T; Akiyama, Y; Ishida, A; Ito, S; Jinno, D; Kikuchi, K; Mishima, E; Moriguchi, T; Saigusa, D; Shima, H; Souma, T; Sugawara, D; Suzuki, C; Suzuki, T; Takeuchi, Y; Tomioka, Y; Toyohara, T; Yamamoto, Y | 1 |
Watanabe, H | 1 |
Niwa, T | 4 |
Furukubo, T; Hiraoka, S; Hosoda, S; Izumi, S; Minegaki, T; Miyoshi, A; Nagano, Y; Nishiguchi, K; Shiraishi, A; Tsujimoto, M; Yamakawa, T | 1 |
Chen, HH; Chuang, CK; Lin, CJ; Liu, HL; Pan, CF; Sun, FJ; Wang, TJ; Wu, CJ | 1 |
Funk, BA; Hostetter, TH; Meyer, TW; Plummer, NS; Sirich, TL | 1 |
Fujiwara, K; Iwasawa, A; Kamachi, T; Kobayashi, T; Kohno, M; Matsumura, Y; Ozawa, T; Tanaka, N; Yanai, H | 1 |
Cheng, BC; Chiou, TT; Hsu, CY; Lee, CT; Lee, YT; Liao, SC; Ng, HY; Tain, YL; Wu, CH; Yang, CC | 1 |
Andersen, GL; DeSantis, TZ; Pahl, M; Piceno, YM; Vaziri, ND; Wong, J | 1 |
Lowenstein, J | 1 |
Hsu, KH; Lee, CC; Sun, CY; Tsai, CJ; Wu, IW; Wu, MS | 1 |
Anraku, M; Hirayama, F; Iohara, D; Maezaki, Y; Maruyama, T; Michihara, A; Otagiri, M; Tomida, H; Tsuchiya, D; Uekama, K | 1 |
Campbell, K; Dimeski, G; Hawley, C; Isbel, N; Johnson, D; McWhinney, B; Pascoe, E; Rossi, M; Stanton, T; Ungerer, J | 1 |
Chen, CK; Chen, CY; Chou, CC; Hsu, HJ; Hsu, KH; Lee, CC; Sun, CY; Tsai, CJ; Wu, IW; Wu, MS; Yen, CH | 1 |
Anraku, M; Hiraga, A; Hirayama, F; Imafuku, T; Iohara, D; Maezaki, Y; Maruyama, T; Nagumo, K; Otagiri, M; Tanaka, M; Uekama, K; Watanabe, H | 1 |
Al Shukaili, A; Al Za'abi, M; Ali, BH; Nemmar, A | 1 |
Banerjee, T; Dolgalev, I; Heguy, A; Jhawar, S; Kassem, H; Lowenstein, J; Ramirez-Valle, F; Singh, P; Torres, D; Zavadil, J | 1 |
Banerjee, T; Coresh, J; Hostetter, TH; Hwang, S; Melamed, ML; Meyer, TW; Parekh, RS; Powe, NR; Shafi, T | 1 |
Anraku, M; Hirayama, F; Iohara, D; Maruyama, T; Otagiri, M; Taguchi, K; Uekama, K; Wada, K | 1 |
Cheng, FP; Chou, CC; Hsieh, MJ; Hsu, WL; Lee, YJ | 1 |
Lin, CJ; Wu, CJ; Wu, PC; Wu, V | 1 |
Ando, Y; Ishida, H; Ito, K; Kurabayashi, M; Negishi, K; Obokata, M; Ogawa, T; Sunaga, H | 1 |
Aviles, DH; Blanchard, EE; Crespo-Salgado, J; Ferris, M; Greenbaum, LA; Kallash, M; Stewart, T; Taylor, CM; Vehaskari, VM; Wang, G; Zhang, Q | 1 |
Chen, J; Ding, X; Ji, J; Liu, T; Teng, J; Zhang, H; Zhang, X | 1 |
Borges, NA; Brito, JS; Carraro-Eduardo, JC; Dolenga, CJ; Mafra, D; Nakao, LS | 1 |
Hsu, CC; Hsu, WL; Huang, PH; Li, SY; Lin, SJ; Lin, YP; Liu, JS; Tarng, DC | 1 |
Beck, GJ; Chertow, GM; Fong, K; Kliger, AS; Larive, B; Levin, NW; Meyer, TW; Plummer, NS; Sirich, TL | 1 |
Banerjee, T; Hostetter, TH; Melamed, M; Meyer, TW; Powe, NR; Shafi, T; Zhu, Y | 1 |
Atoh, K; Haneda, M; Itoh, H | 1 |
Dhondt, A; Eloot, S; Hostetter, T; Meert, N; Meyer, T; Van Biesen, W; Vanholder, R | 1 |
Enomoto, A; Muteliefu, G; Niwa, T | 1 |
De Preter, V; Evenepoel, P; Meijers, BK; Vanrenterghem, Y; Verbeke, K | 1 |
Bammens, B; De Loor, H; Evenepoel, P; Meijers, BK; Vanrenterghem, Y; Verbeke, K | 1 |
Ezawa, A; Itoh, Y; Kikuchi, K; Murakami, K; Niwa, T; Tateoka, R | 2 |
Adrahtas, A; Kelly, DJ; Kompa, AR; Krum, H; Lekawanvijit, S; Wang, BH | 1 |
Benet, LZ; Frassetto, LA; Huang, Y; Sun, H | 1 |
Fasching, A; Fujita, T; Hansell, P; Kawakami, T; Nangaku, M; Nishijima, F; Nordquist, L; Palm, F; Tanaka, T | 1 |
Adijiang, A; Bolati, D; Dateki, M; Enomoto, A; Nishijima, F; Niwa, T; Shimizu, H | 1 |
Furukubo, T; Higuchi, K; Hirata, S; Izumi, S; Nishiguchi, K; Otagiri, M; Shima, D; Takara, K; Tsujimoto, M; Yamakawa, T; Yokota, H | 1 |
Hsu, HJ; Hsu, KH; Lee, CC; Lin, CY; Sun, CY; Tsai, CJ; Tzen, CY; Wang, YC; Wu, IW; Wu, MS | 1 |
Fujii, H; Fukagawa, M; Goto, S; Kita, T; Yoshiya, K | 1 |
Chen, HH; Chuang, CK; Lin, CJ; Pan, CF; Sun, FJ; Wang, TJ; Wu, CJ | 1 |
Argilés, A; Bergé-Lefranc, D; Brunet, P; Calaf, R; Cerini, C; Charpiot, P; Dignat-George, F; Dou, L; Génovésio, C; Gondouin, B; Jourde-Chiche, N; Morange, S; Rathelot, P; Verhaeghe, P | 1 |
Chiang, CK; Fujita, T; Inagi, R; Nangaku, M; Tanaka, T | 1 |
Kiss, I | 1 |
Chiang, CK; Nangaku, M; Tanaka, T | 1 |
Adelibieke, Y; Bolati, D; Muteliefu, G; Niwa, T; Shimizu, H | 1 |
Glorieux, G; Neirynck, N; Pletinck, A; Schepers, E; Vanholder, R | 1 |
Niwa, T; Shimizu, H | 1 |
Schulman, G | 2 |
Bolati, D; Niwa, T; Shimizu, H | 1 |
Fujita, T; Ikeda, Y; Ishihara, K; Kobayashi, M; Kumagai, Y; Maeda, M; Majima, M; Nakamura, T; Sahashi, K; Yasuda, S | 1 |
Chang, SC; Sun, CY; Wu, MS | 1 |
Chen, CH; Cheng, CH; Chuang, YW; Huang, ST; Shu, KH; Wu, MJ; Yu, TM | 1 |
Ishima, Y; Kadowaki, D; Kotani, S; Maruyama, T; Miyamoto, Y; Miyamura, S; Nakajima, M; Noguchi, T; Otagiri, M; Watanabe, H | 1 |
Chen, HH; Chuang, CK; Jayakumar, T; Lin, CJ; Liu, HL; Pan, CF; Wang, TJ; Wu, CJ | 1 |
Balcells, M; Bosch, I; Chitalia, VC; Edelman, ER; Kolandaivelu, K; Martorell, J; Shivanna, S | 1 |
Annaert, P; de Loor, H; Evenepoel, P; Meijers, B; Poesen, R; Viaene, L | 1 |
Imai, E; Oka, K; Okada, N; Shoji, T; Takabatake, Y; Takahito, I; Togawa, M; Tsubakihara, Y | 1 |
Hosokawa, A; Motojima, M; Muraki, T; Yamato, H; Yoshioka, T | 1 |
Deguchi, T; Nakamura, M; Otagiri, M; Suenaga, A; Tsutsumi, Y | 1 |
Berland, Y; Brunet, P; Cerini, C; Dignat-George, F; Dou, L; Faure, V; Sabatier, F; Sampol, J | 1 |
Ahmed, IH; Ali, BH | 1 |
Enomoto, A; Miglinas, M; Nakamura, S; Niwa, T; Taki, K | 1 |
Iida, S; Kohno, K; Miyazaki, H; Nishida, H; Okuda, S; Tamaki, K; Ueda, S; Usui, M; Yoshimura, J | 1 |
Anraku, M; Fukunaga, E; Hashimoto, M; Kitamura, K; Maruyama, T; Otagiri, M; Shimoishi, K; Taguchi, K; Tasaki, Y | 1 |
Enomoto, A; Niwa, T | 1 |
Hostetter, TH; Meyer, TW; Pham, NM; Recht, NS | 1 |
Niwa, T; Tumur, Z | 1 |
Bannai, K; Goto, S; Hayashi, H; Nishijima, F; Niwa, T; Owada, S | 1 |
Kawai, K; Nishii, R; Nishio, T; Takamura, N; Tokunaga, J; Yoshimoto, M | 1 |
Hostetter, TH; Lieu, S; Melamed, ML; Meyer, TW; Ponda, M; Quan, Z; Raff, AC | 1 |
Bernard, BF; de Jong, M; Docter, R; Hennemann, G; Krenning, EP; Lim, CF | 1 |
Agatsuma, S; Sekino, H; Watanabe, H | 1 |
Miyazaki, T; Niwa, T; Nomura, T; Sugiyama, S; Tsukushi, S; Tsutsui, S | 1 |
Endo, K; Hirata, M; Ise, M; Ito, Y; Miyazaki, T; Niwa, T; Seo, H | 1 |
Hara, Y; Iitaka, M; Katayama, S; Kawakami, Y; Kawasaki, S; Kitahama, S; Kuriyama, R; Miura, S; Sakurai, S; Yamanaka, K | 1 |
Maruyama, T; Otagiri, M; Shimada, H; Takadate, A; Tsutsumi, Y | 1 |
Aoyama, I; Niwa, T | 1 |
Barsotti, G; Giovannetti, S | 1 |
Gulyassy, PF; Jarrard, E; Stanfel, LA | 1 |
Jensen, OM | 1 |
Black, DA | 1 |
17 review(s) available for indican and Kidney Failure, Chronic
Article | Year |
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Topics: Cardiovascular Diseases; Cohort Studies; Cresols; Follow-Up Studies; Humans; Indican; Kidney Failure, Chronic; Peritoneal Dialysis; Peritonitis; Prospective Studies; Sulfates; Sulfuric Acid Esters | 2022 |
Possible Effects of Uremic Toxins p-Cresol, Indoxyl Sulfate, p-Cresyl Sulfate on the Development and Progression of Colon Cancer in Patients with Chronic Renal Failure.
Topics: Colonic Neoplasms; Humans; Indican; Inflammation; Kidney Failure, Chronic; Renal Insufficiency, Chronic; Sulfates; Uremic Toxins | 2023 |
Generation, clearance, toxicity, and monitoring possibilities of unaccounted uremic toxins for improved dialysis prescriptions.
Topics: Humans; Indican; Kidney Failure, Chronic; Renal Dialysis; Toxins, Biological; Urea; Uremia | 2018 |
[Research progress of the uremic toxin indoxyl sulfate in cardiovascular complication of end-stage renal diseases].
Topics: Cardiovascular Diseases; Humans; Indican; Kidney Failure, Chronic; Oxidative Stress; Toxins, Biological | 2018 |
Molecular mechanisms for uremic toxin-induced oxidative tissue damage via a cardiovascular-renal connection.
Topics: Cardiovascular Diseases; Cresols; Humans; Indican; Kidney Failure, Chronic; Oxidation-Reduction; Oxidative Stress; Sulfuric Acid Esters | 2013 |
Targeting protein-bound uremic toxins in chronic kidney disease.
Topics: Bone and Bones; Carbon; Cardiovascular System; Disease Progression; Erythropoietin; Humans; Indican; Kidney; Kidney Failure, Chronic; Oxides; Protein Binding; Reactive Oxygen Species | 2013 |
Meta-Analysis of the Associations of p-Cresyl Sulfate (PCS) and Indoxyl Sulfate (IS) with Cardiovascular Events and All-Cause Mortality in Patients with Chronic Renal Failure.
Topics: Biomarkers; Cardiovascular Diseases; Cresols; Humans; Indican; Kidney Failure, Chronic; Risk Factors; Sulfuric Acid Esters; Toxins, Biological; Uremia | 2015 |
The role of carbon adsorbent in the conservative management of chronic kidney disease.
Topics: Adsorption; Animals; Carbon; Conservative Treatment; Disease Progression; Humans; Indican; Kidney Failure, Chronic; Mice; Oxidative Stress; Oxides; Patient Safety; Rats; Reactive Oxygen Species | 2017 |
Uremic toxins and oral adsorbents.
Topics: Administration, Oral; Animals; Carbon; Chelating Agents; Humans; Indican; Kidney Failure, Chronic; Mice; Oxides; Polyamines; Protein Binding; Sevelamer; Uremia | 2011 |
[The uremic toxin, indoxyl sulfate, signifies cardio-renal risk and intestinal-renal relationship].
Topics: Biomarkers; Cardiovascular Diseases; Disease Progression; Humans; Indican; Intestinal Mucosa; Intestines; Kidney; Kidney Failure, Chronic; Risk Factors; Uremia | 2011 |
Dysregulated oxygen metabolism of the kidney by uremic toxins: review.
Topics: Animals; Cell Proliferation; Erythropoietin; Homeostasis; Humans; Hypoxia; Indican; Kidney; Kidney Failure, Chronic; Kidney Tubules; Oxidative Stress; Oxygen Consumption; Rats; Uremia | 2012 |
An update on protein-bound uremic retention solutes.
Topics: Adsorption; Blood Proteins; Carbon; Cresols; Humans; Indican; Kidney Failure, Chronic; Microspheres; Oxides; Protein Binding; Renal Dialysis; Sulfuric Acid Esters; Uremia | 2012 |
Indoxyl sulfate induces nephrovascular senescence.
Topics: Animals; Aorta; Cardiovascular Diseases; Cellular Senescence; Endothelial Cells; Gene Expression; Glucuronidase; Humans; Hypertension; Indican; Kidney Failure, Chronic; Kidney Tubules, Proximal; Klotho Proteins; NF-kappa B; Nitric Oxide; Rats; Reactive Oxygen Species; Uremia | 2012 |
A nexus of progression of chronic kidney disease: tryptophan, profibrotic cytokines, and charcoal.
Topics: Adsorption; Carbon; Disease Progression; Fibrosis; Humans; Indican; Intestinal Absorption; Kidney Failure, Chronic; Microspheres; Oxides; Renin-Angiotensin System; Transforming Growth Factor beta; Tryptophan | 2012 |
[Oral sorbent].
Topics: Administration, Oral; Adsorption; Animals; Carbon; Clinical Trials as Topic; Contraindications; Humans; Indican; Kidney Failure, Chronic; Kidney Tubules, Proximal; Organic Anion Transporters; Oxides; Transforming Growth Factor beta | 2004 |
Roles of organic anion transporters in the progression of chronic renal failure.
Topics: Animals; Biological Transport; Bone Diseases; Humans; Indican; Kidney Failure, Chronic; Organic Anion Transporters; Toxins, Biological; Uremia | 2007 |
Uremic intoxication.
Topics: Amines; Animals; Creatinine; Dogs; Guanidines; Humans; Hydroxy Acids; Indican; Kidney Failure, Chronic; Molecular Weight; Phenols; Renal Dialysis; Toxins, Biological; Urea; Uremia; Uric Acid | 1975 |
17 trial(s) available for indican and Kidney Failure, Chronic
Article | Year |
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Intradialytic Protein Ingestion and Exercise do Not Compromise Uremic Toxin Removal Throughout Hemodialysis.
Topics: Aged; Aged, 80 and over; Creatinine; Cystatin C; Eating; Exercise; Humans; Indican; Kidney Failure, Chronic; Middle Aged; Phosphates; Polyesters; Renal Dialysis; Urea; Uremic Toxins | 2023 |
Low-protein diet supplemented with inulin lowers protein-bound toxin levels in patients with stage 3b-5 chronic kidney disease: a randomized controlled study.
Topics: Diet, Protein-Restricted; Dietary Proteins; Dietary Supplements; Humans; Indican; Inflammation; Inulin; Kidney Failure, Chronic; Renal Insufficiency, Chronic | 2023 |
Improved β2-Microglobulin and Phosphorous Removal with Expanded Hemodialysis and Online Hemodiafiltration versus High-Flux Hemodialysis: A Cross-Over Randomized Clinical Trial.
Topics: beta 2-Microglobulin; Cross-Over Studies; Hemodiafiltration; Humans; Indican; Interleukin-10; Interleukin-6; Kidney Failure, Chronic; Phosphates; Phosphorus; Prospective Studies; Renal Dialysis; Serum Albumin | 2023 |
Adsorption of Protein-Bound Uremic Toxins Through Direct Hemoperfusion With Hexadecyl-Immobilized Cellulose Beads in Patients Undergoing Hemodialysis.
Topics: Adsorption; Aged; Blood Proteins; Cellulose; Cresols; Feasibility Studies; Female; Hemoperfusion; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Male; Middle Aged; Porosity; Protein Binding; Renal Dialysis; Serum Albumin; Sulfuric Acid Esters; Toxins, Biological; Uremia | 2018 |
Results of the HEMO Study suggest that p-cresol sulfate and indoxyl sulfate are not associated with cardiovascular outcomes.
Topics: Adult; Aged; Cardiovascular Diseases; Cresols; Female; Glutamine; Hippurates; Humans; Indican; Kidney Failure, Chronic; Longitudinal Studies; Male; Middle Aged; Renal Dialysis; Risk Factors; Serum Albumin; Sulfuric Acid Esters; Uremia | 2017 |
Shen-Shuai-Ning granule decreased serum concentrations of indoxyl sulphate in uremic patients undergoing peritoneal dialysis.
Topics: Adult; Cresols; Drugs, Chinese Herbal; Female; Humans; Indican; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Peritoneal Dialysis; Sulfuric Acid Esters; Treatment Outcome; Uremia | 2018 |
Oral adsorbent AST-120 potentiates the effect of erythropoietin-stimulating agents on Stage 5 chronic kidney disease patients: a randomized crossover study.
Topics: Adult; Aged; Anemia; Carbon; Cross-Over Studies; Drug Synergism; Epoetin Alfa; Erythropoietin; Female; Hemoglobins; Humans; Indican; Kidney; Kidney Failure, Chronic; Male; Microspheres; Middle Aged; Oxides; Polyethylene Glycols; Recombinant Proteins | 2014 |
Effects of chitosan on oxidative stress and related factors in hemodialysis patients.
Topics: Aged; Antioxidants; Chitosan; Humans; Hyperphosphatemia; Indican; Kidney Failure, Chronic; Middle Aged; Oxidative Stress; Phosphates; Renal Dialysis; Serum Albumin; Treatment Outcome | 2014 |
Limited reduction in uremic solute concentrations with increased dialysis frequency and time in the Frequent Hemodialysis Network Daily Trial.
Topics: Adult; Cresols; Female; Humans; Indican; Kidney Failure, Chronic; Male; Metabolomics; Middle Aged; Renal Dialysis; Sulfuric Acid Esters; Time Factors; Uremia | 2017 |
Free and total p-cresol sulfate levels and infectious hospitalizations in hemodialysis patients in CHOICE and HEMO.
Topics: Adult; Aged; Aged, 80 and over; Cresols; Female; Gastrointestinal Diseases; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Patient Admission; Sepsis; Young Adult | 2017 |
p-Cresyl sulfate serum concentrations in haemodialysis patients are reduced by the prebiotic oligofructose-enriched inulin.
Topics: Administration, Oral; Aged; Cresols; Female; Humans; Indican; Inulin; Kidney Failure, Chronic; Male; Middle Aged; Oligosaccharides; Prebiotics; Renal Dialysis; Sulfuric Acid Esters | 2010 |
Hepatic clearance, but not gut availability, of erythromycin is altered in patients with end-stage renal disease.
Topics: Administration, Oral; Adult; Aged; Biological Availability; Case-Control Studies; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Interactions; Erythromycin; Female; Furans; Humans; Indican; Infusions, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Propionates; Tissue Distribution | 2010 |
A nexus of progression of chronic kidney disease: charcoal, tryptophan and profibrotic cytokines.
Topics: Administration, Oral; Adult; Aged; Carbon; Cytokines; Endpoint Determination; Female; Fibrosis; Humans; Indican; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Oxides; Tryptophan | 2006 |
Elevation of circulating endothelial microparticles in patients with chronic renal failure.
Topics: Adult; Aged; Aged, 80 and over; Annexin A5; Antigens, CD; Cadherins; CD146 Antigen; Cells, Cultured; Cresols; Endothelial Cells; Female; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Particle Size; Renal Dialysis; Toxins, Biological; Uremia | 2006 |
Carbonic-adsorbent AST-120 reduces overload of indoxyl sulfate and the plasma level of TGF-beta1 in patients with chronic renal failure.
Topics: Adsorption; Aged; Carbon; Female; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Oxides; Transforming Growth Factor beta1 | 2006 |
Removal of the protein-bound solutes indican and p-cresol sulfate by peritoneal dialysis.
Topics: Adult; Aged; Blood Proteins; Cresols; Dialysis Solutions; Female; Humans; Indican; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Sulfuric Acid Esters; Treatment Outcome | 2008 |
Influences of haemodialysis on the binding sites of human serum albumin: possibility of an efficacious administration plan using binding inhibition.
Topics: Adult; Aged; Barbiturates; Binding Sites; Carbon Radioisotopes; Diazepam; Diuretics; Fatty Acids, Nonesterified; Female; Furans; Furosemide; Hippurates; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Propionates; Protein Binding; Renal Dialysis; Serum Albumin; Treatment Outcome; Warfarin | 2008 |
86 other study(ies) available for indican and Kidney Failure, Chronic
Article | Year |
---|---|
Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney.
Topics: Animals; Anions; Biological Transport; Dose-Response Relationship, Drug; Female; Furans; Indican; Kidney; Kidney Failure, Chronic; Male; Oocytes; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Probenecid; Propionates; Rats; Rats, Wistar; Toxins, Biological; Tritium; Uremia; Uricosuric Agents; Xenopus laevis | 2002 |
Modeling indoxyl sulfate transport in a bioartificial kidney: Two-step binding kinetics or lumped parameters model for uremic toxin clearance?
Topics: Humans; Indican; Kidney; Kidney Failure, Chronic; Kinetics; Toxins, Biological | 2021 |
The Accumulation of Gut Microbiome-derived Indoxyl Sulfate and P-Cresyl Sulfate in Patients With End-stage Renal Disease.
Topics: Cresols; Dialysis Solutions; Gastrointestinal Microbiome; Humans; Indican; Indoles; Kidney Failure, Chronic; Renal Insufficiency, Chronic; RNA, Ribosomal, 16S; Sulfates; Sulfuric Acid Esters; Tryptophan | 2022 |
The Binding of Aripiprazole to Plasma Proteins in Chronic Renal Failure Patients.
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Aripiprazole; Blood Proteins; Case-Control Studies; Cresols; Female; Humans; Indican; Kidney Failure, Chronic; Male; Protein Binding; Retrospective Studies; Serum Albumin, Human; Sulfuric Acid Esters; Young Adult | 2021 |
Increased clearance of indoxyl sulphate in renal failure rats with the addition of water-soluble poly-β-cyclodextrin to the dialysate.
Topics: Animals; beta-Cyclodextrins; Dialysis Solutions; Indican; Kidney Failure, Chronic; Male; Rats; Rats, Sprague-Dawley; Renal Dialysis; Water | 2022 |
Mechanistic Study on the Effect of Renal Impairment on the Pharmacokinetics of Vildagliptin and its Carboxylic Acid Metabolite.
Topics: Animals; Carboxylic Acids; Dipeptidyl-Peptidase IV Inhibitors; Indican; Kidney Failure, Chronic; Organic Anion Transporters; Rats; Vildagliptin | 2022 |
Correlation of inflammatory biomarkers with the diversity of Bacteroidaceae, Bifidobacteriaceae, Prevotellaceae and Lactobacillaceae families in the intestinal microbiota of patients with end stage renal disease.
Topics: Antioxidants; Bacteroidaceae; Biomarkers; Gastrointestinal Microbiome; Humans; Indican; Interleukin-1; Interleukin-6; Kidney Failure, Chronic; Lactobacillaceae; RNA, Ribosomal, 16S; Tumor Necrosis Factor-alpha | 2022 |
Treatment with Paracetamol Can Interfere with the Intradialytic Optical Estimation in Spent Dialysate of Uric Acid but Not of Indoxyl Sulfate.
Topics: Acetaminophen; Dialysis Solutions; Hemodiafiltration; Humans; Indican; Kidney Failure, Chronic; Renal Dialysis; Uric Acid | 2022 |
Identification and characterisation of fluorescent substances in spent dialysis fluid.
Topics: Chromatography, High Pressure Liquid; Dialysis Solutions; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Renal Dialysis; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2020 |
Serum Levels and Removal by Haemodialysis and Haemodiafiltration of Tryptophan-Derived Uremic Toxins in ESKD Patients.
Topics: Adult; Aged; Aged, 80 and over; Female; Hemodiafiltration; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis; Renal Insufficiency, Chronic; Tryptophan | 2020 |
Improved cardiovascular autonomic function and decreased protein-bound uremic toxins in patients with end-stage renal disease after peritoneal dialysis.
Topics: Cresols; Humans; Indican; Kidney Failure, Chronic; Peritoneal Dialysis; Renal Dialysis; Sulfuric Acid Esters | 2020 |
New oral spherical carbon adsorbent effectively reduces serum indoxyl sulfate levels in moderate to advanced chronic kidney disease patients: a multicenter, prospective, open-label study.
Topics: Adsorption; Aged; Carbon; Female; Glomerular Filtration Rate; Hemoglobins; Humans; Indican; Kidney Failure, Chronic; Male; Microspheres; Middle Aged; Prospective Studies; Renal Insufficiency, Chronic; Severity of Illness Index | 2020 |
Indoxyl Sulfate-Mediated Metabolic Alteration of Transcriptome Signatures in Monocytes of Patients with End-Stage Renal Disease (ESRD).
Topics: Aged; Case-Control Studies; Energy Metabolism; Female; Gene Expression Profiling; Gene Regulatory Networks; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Monocytes; Protein Interaction Maps; Toxins, Biological; Transcriptome; Up-Regulation; Uremia | 2020 |
Indoxyl Sulfate and Incident Peripheral Artery Disease in Hemodialysis Patients.
Topics: Aged; Aged, 80 and over; Biomarkers; Cause of Death; Female; Humans; Incidence; Indican; Kidney Failure, Chronic; Male; Middle Aged; Peripheral Arterial Disease; Prognosis; Prospective Studies; Renal Dialysis; Risk Assessment; Risk Factors; Taiwan; Time Factors; Up-Regulation | 2020 |
Evaluation of Salivary Indoxyl Sulfate with Proteinuria for Predicting Graft Deterioration in Kidney Transplant Recipients.
Topics: Adult; Biomarkers; Chromatography, Liquid; Cresols; Female; Graft Rejection; Humans; Indican; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Poland; Predictive Value of Tests; Proteinuria; Saliva; Toxins, Biological | 2021 |
Microbiome perturbation by oral vancomycin reduces plasma concentration of two gut-derived uremic solutes, indoxyl sulfate and p-cresyl sulfate, in end-stage renal disease.
Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Biomarkers; Cresols; Female; Gastrointestinal Microbiome; Humans; Indican; Kidney Failure, Chronic; Male; Metagenome; Middle Aged; Molecular Typing; Pilot Projects; RNA, Ribosomal, 16S; Sulfuric Acid Esters; Vancomycin | 2017 |
Indoxyl sulfate (IS)-mediated immune dysfunction provokes endothelial damage in patients with end-stage renal disease (ESRD).
Topics: Adult; Aged; Apoptosis; Case-Control Studies; CD4-Positive T-Lymphocytes; Cells, Cultured; Chemokine CXCL1; CX3C Chemokine Receptor 1; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Receptors, Aryl Hydrocarbon; Tumor Necrosis Factor-alpha | 2017 |
Indoxyl sulfate accelerates vascular smooth muscle cell calcification via microRNA-29b dependent regulation of Wnt/β-catenin signaling.
Topics: beta Catenin; Cell Culture Techniques; Cells, Cultured; Down-Regulation; Humans; Indican; Kidney Failure, Chronic; MicroRNAs; Muscle, Smooth, Vascular; Radial Artery; Signal Transduction; Vascular Calcification; Wnt Proteins | 2018 |
Impact of the Oral Adsorbent AST-120 on Organ-Specific Accumulation of Uremic Toxins: LC-MS/MS and MS Imaging Techniques.
Topics: Administration, Oral; Adsorption; Animals; Carbon; Chromatography, Liquid; Cresols; Indican; Kidney Failure, Chronic; Male; Mice, Inbred C57BL; Oxides; Sulfuric Acid Esters; Tandem Mass Spectrometry; Toxins, Biological; Uremia | 2017 |
Echocardiography-based pressure-volume loop assessment in the evaluation for the effects of indoxyl sulfate on cardiovascular function.
Topics: Aged; Biomarkers; Echocardiography; Female; Follow-Up Studies; Humans; Hypertrophy, Left Ventricular; Indican; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Contraction; Prognosis; Renal Dialysis; Stroke Volume; Systole; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling | 2019 |
Increasing the removal of protein-bound uremic toxins by liposome-supported hemodialysis.
Topics: Animals; Cresols; Dialysis Solutions; Equipment Design; Hippurates; Indican; Kidney Failure, Chronic; Liposomes; Male; Rats, Sprague-Dawley; Renal Dialysis; Sulfuric Acid Esters; Toxins, Biological; Uremia | 2019 |
Retained organic solutes, patient characteristics and all-cause and cardiovascular mortality in hemodialysis: results from the retained organic solutes and clinical outcomes (ROSCO) investigators.
Topics: Adult; Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Female; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome | 2013 |
Indoxyl sulfate down-regulates SLCO4C1 transporter through up-regulation of GATA3.
Topics: Animals; Biological Transport; Carbon; Cell Line; Disease Models, Animal; Down-Regulation; GATA3 Transcription Factor; Gene Expression Regulation; Humans; Indican; Kidney Failure, Chronic; Organic Anion Transporters; Oxides; Rats; Toxins, Biological | 2013 |
Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease.
Topics: Cell Line, Tumor; Cytochrome P-450 CYP3A; Erythromycin; Furans; Hippurates; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Liver; Microsomes, Liver; Pregnane X Receptor; Propionates; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger; Steroid Hydroxylases; Toxins, Biological; Vitamin D; Vitamin D3 24-Hydroxylase | 2013 |
Gastrointestinal-related uremic toxins in peritoneal dialysis: a pilot study with a 5-year follow-up.
Topics: Adult; Cardiovascular Diseases; Cresols; Female; Follow-Up Studies; Humans; Indican; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Pilot Projects; Prognosis; Sulfuric Acid Esters | 2013 |
Prominent accumulation in hemodialysis patients of solutes normally cleared by tubular secretion.
Topics: Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Cresols; Female; Glutamine; Hippurates; Humans; Indican; Kidney Failure, Chronic; Kidney Tubules; Male; Middle Aged; Models, Statistical; Renal Dialysis | 2014 |
Exploration of novel predictive markers in rat plasma of the early stages of chronic renal failure.
Topics: Adenine; Adenosine; Animals; Biomarkers; Chromatography, Liquid; Cresols; Early Diagnosis; Glycocholic Acid; Indican; Kidney Failure, Chronic; Lysophospholipids; Male; Metabolomics; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Sulfuric Acid Esters; Tandem Mass Spectrometry | 2014 |
Effects of AST-120 on blood concentrations of protein-bound uremic toxins and biomarkers of cardiovascular risk in chronic dialysis patients.
Topics: Adsorption; Adult; Biomarkers; Carbon; Cardiovascular Diseases; Cresols; Cytokine TWEAK; Female; Humans; Indican; Interleukin-6; Kidney Failure, Chronic; Male; Malondialdehyde; Middle Aged; Oxides; Protein Binding; Renal Dialysis; Risk Factors; Sulfuric Acid Esters; Tumor Necrosis Factors; Uremia | 2014 |
Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD.
Topics: Adult; Aged; Ammonia; Cresols; Diet; Fatty Acids, Volatile; Female; Humans; Indican; Indoles; Inflammation; Intestines; Kidney Failure, Chronic; Male; Microbiota; Middle Aged; Sulfuric Acid Esters; Urate Oxidase; Urea; Urease | 2014 |
Agent Orange and heart disease: is there a connection?
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Agent Orange; Binding, Competitive; Coronary Disease; Defoliants, Chemical; Humans; Indican; Kidney Failure, Chronic; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Signal Transduction; Veterans; Vietnam Conflict | 2014 |
Antioxidant and renoprotective activity of chitosan in nephrectomized rats.
Topics: Animals; Antioxidants; Chitosan; Indican; Iron; Kidney Failure, Chronic; Male; Nephrectomy; Oxidation-Reduction; Oxidative Stress; Rats; Serum Albumin | 2012 |
Uraemic toxins and cardiovascular disease across the chronic kidney disease spectrum: an observational study.
Topics: Aged; Biomarkers; Brachial Artery; Cardiovascular Diseases; Carotid Intima-Media Thickness; Cresols; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Indican; Kidney Failure, Chronic; Logistic Models; Male; Middle Aged; Multivariate Analysis; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors; Sulfuric Acid Esters; Vascular Stiffness | 2014 |
The association of uremic toxins and inflammation in hemodialysis patients.
Topics: Aged; Comorbidity; Coronary Artery Disease; Creatinine; Cresols; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Indican; Inflammation; Inflammation Mediators; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Sulfuric Acid Esters | 2014 |
High-mobility group box-1 protein in adenine-induced chronic renal failure and the influence of gum arabic thereon.
Topics: Adenine; Animals; Biomarkers; Creatinine; Disease Models, Animal; Gum Arabic; HMGB1 Protein; Indican; Inflammation Mediators; Kidney; Kidney Failure, Chronic; Male; Rats, Wistar; Time Factors; Urea | 2015 |
Functional genomic analysis identifies indoxyl sulfate as a major, poorly dialyzable uremic toxin in end-stage renal disease.
Topics: Adult; Aged; Animals; Cell Line; Chromatography, High Pressure Liquid; Culture Media; Female; Gene Expression Regulation; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Plasma; Probenecid; Renal Dialysis; Swine; Uremia | 2015 |
Free Levels of Selected Organic Solutes and Cardiovascular Morbidity and Mortality in Hemodialysis Patients: Results from the Retained Organic Solutes and Clinical Outcomes (ROSCO) Investigators.
Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Cause of Death; Cresols; Female; Glutamine; Hippurates; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Morbidity; Mortality; Patient Outcome Assessment; Renal Dialysis; Sulfuric Acid Esters; United States | 2015 |
Antioxidant and renoprotective activity of 2-hydroxypropyl-β-cyclodextrin in nephrectomized rats.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Antioxidants; beta-Cyclodextrins; Biomarkers; Blood Urea Nitrogen; Creatinine; Cytoprotection; Disease Models, Animal; Indican; Indoles; Kidney; Kidney Failure, Chronic; Male; Nephrectomy; Oxidation-Reduction; Oxidative Stress; Proton Magnetic Resonance Spectroscopy; Rats; Serum Albumin; Time Factors | 2016 |
Detection of indoxyl sulfate levels in dogs and cats suffering from naturally occurring kidney diseases.
Topics: Animals; Biomarkers; Cats; Chromatography, High Pressure Liquid; Dogs; Indican; Kidney Failure, Chronic | 2015 |
Independent and incremental prognostic value of novel cardiac biomarkers in chronic hemodialysis patients.
Topics: Aged; Biomarkers; Cardiovascular Diseases; Cause of Death; Female; Galectin 3; Humans; Indican; Interleukin-1 Receptor-Like 1 Protein; Kidney Failure, Chronic; Male; Middle Aged; Mortality; Natriuretic Peptide, Brain; Peptide Fragments; Prognosis; Prospective Studies; Renal Dialysis; Risk Factors; ROC Curve; Stroke Volume | 2016 |
Intestinal microbiota in pediatric patients with end stage renal disease: a Midwest Pediatric Nephrology Consortium study.
Topics: Actinobacteria; Adolescent; Bacterial Load; Bacteroidetes; C-Reactive Protein; Child; Child, Preschool; Cresols; Feces; Female; Firmicutes; Gastrointestinal Microbiome; Humans; Indican; Intestines; Kidney Failure, Chronic; Kidney Transplantation; Lactic Acid; Male; Peritoneal Dialysis; Proteobacteria; RNA, Ribosomal, 16S; Sulfuric Acid Esters; Uremia; Verrucomicrobia | 2016 |
Indoxyl Sulfate Enhance the Hypermethylation of Klotho and Promote the Process of Vascular Calcification in Chronic Kidney Disease.
Topics: Animals; Cell Line; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Glucuronidase; Humans; Indican; Kidney Failure, Chronic; Klotho Proteins; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Vascular Calcification | 2016 |
Is there a relationship between tryptophan dietary intake and plasma levels of indoxyl sulfate in chronic kidney disease patients on hemodialysis?
Topics: Cross-Sectional Studies; Diet; Female; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Tryptophan | 2016 |
High Uric Acid Ameliorates Indoxyl Sulfate-Induced Endothelial Dysfunction and Is Associated with Lower Mortality among Hemodialysis Patients.
Topics: Adult; Aged; Biomarkers; Cause of Death; Cells, Cultured; Chi-Square Distribution; Endothelial Cells; Female; Humans; Hyperuricemia; Indican; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Middle Aged; Multivariate Analysis; Nitric Oxide; Oxidative Stress; Prevalence; Prognosis; Proportional Hazards Models; Registries; Risk Factors; Taiwan; Time Factors; Up-Regulation; Uric Acid | 2017 |
Serum indoxyl sulfate levels in patients with diabetic nephropathy: relation to renal function.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diagnostic Techniques, Endocrine; Disease Progression; Female; Glomerular Filtration Rate; Humans; Indican; Kidney; Kidney Failure, Chronic; Male; Middle Aged | 2009 |
Why do patients on peritoneal dialysis have low blood levels of protein-bound solutes?
Topics: Cresols; Humans; Indican; Kidney Failure, Chronic; Peritoneal Dialysis; Renal Dialysis; Sulfuric Acid Esters; Uremia | 2009 |
Indoxyl sulfate promotes proliferation of human aortic smooth muscle cells by inducing oxidative stress.
Topics: Antioxidants; Aortic Valve Stenosis; Cardiovascular Diseases; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Indican; Kidney Failure, Chronic; Muscle, Smooth, Vascular; Oxidative Stress | 2009 |
p-Cresyl sulfate and indoxyl sulfate in hemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cohort Studies; Cresols; Female; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Models, Biological; Renal Dialysis; Serum Albumin; Sulfuric Acid Esters; Urea | 2009 |
Metabolomic analysis of uremic toxins by liquid chromatography/electrospray ionization-tandem mass spectrometry.
Topics: Animals; Chromatography, Liquid; Cresols; Disease Models, Animal; Hippurates; Humans; Indican; Kidney; Kidney Failure, Chronic; Male; Metabolomics; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Sulfuric Acid Esters; Toxins, Biological | 2010 |
Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes?
Topics: Animals; Blotting, Western; Cardiomyopathy, Hypertrophic; Cell Survival; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Fibroblasts; Indican; Kidney Failure, Chronic; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; RNA, Messenger; Toxins, Biological | 2010 |
Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress.
Topics: Acetophenones; Animals; Carbon; Cell Hypoxia; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Humans; Indican; Indoles; Kidney Failure, Chronic; Kidney Tubules, Proximal; Male; NADPH Oxidases; Nephrectomy; Ouabain; Oxidative Stress; Oxides; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Time Factors; Uremia | 2010 |
Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate.
Topics: Acetylcysteine; Animals; Benzothiazoles; Cell Line; Cell Proliferation; Cellular Senescence; Fibrosis; Humans; Indican; Kidney Failure, Chronic; Kidney Tubules, Proximal; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Toluene; Tumor Suppressor Protein p53 | 2010 |
Inhibitory effects of uraemic toxins 3-indoxyl sulfate and p-cresol on losartan metabolism in vitro.
Topics: Angiotensin II Type 1 Receptor Blockers; Aryl Hydrocarbon Hydroxylases; Cresols; Cytochrome P-450 CYP2C9; Humans; Imidazoles; In Vitro Techniques; Indican; Kidney Failure, Chronic; Losartan; Microsomes, Liver; Renal Dialysis; Tetrazoles; Uremia | 2010 |
Metabolomic search for uremic toxins as indicators of the effect of an oral sorbent AST-120 by liquid chromatography/tandem mass spectrometry.
Topics: Adsorption; Animals; Carbon; Chromatography, Liquid; Hippurates; Indican; Kidney Failure, Chronic; Male; Metabolomics; Oxides; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Toxins, Biological; Uremia | 2010 |
p-Cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease.
Topics: Aged; Biomarkers; Cohort Studies; Creatinine; Cresols; Disease Progression; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Indican; Kidney Failure, Chronic; Kidney Function Tests; Male; Prognosis; Prospective Studies; Risk Factors; Sulfuric Acid Esters; Survival Rate; Uremia | 2011 |
p-Cresylsulfate and indoxyl sulfate level at different stages of chronic kidney disease.
Topics: Cohort Studies; Cresols; Female; Humans; Indican; Kidney Failure, Chronic; Linear Models; Male; Middle Aged; Multivariate Analysis; Sulfuric Acid Esters | 2011 |
Determination of uremic solutes in biological fluids of chronic kidney disease patients by HPLC assay.
Topics: Aged; Chromatography, High Pressure Liquid; Cresols; Female; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Male; Middle Aged; Phenol; Phenols; Sulfuric Acid Esters; Uremia | 2011 |
Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner.
Topics: Animals; Blotting, Western; Cobalt; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Gene Expression Regulation; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1; Indican; Indoles; Kidney Failure, Chronic; Luciferases; Oxygen; Rats; Uremia | 2011 |
Indoxyl sulfate induces endothelial cell senescence by increasing reactive oxygen species production and p53 activity.
Topics: Arginine; Cellular Senescence; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Indican; Kidney Failure, Chronic; Nitric Oxide Synthase; Reactive Oxygen Species; Tumor Suppressor Protein p53 | 2012 |
AST-120 ameliorates epithelial-to-mesenchymal transition and interstitial fibrosis in the kidneys of chronic kidney disease rats.
Topics: Actins; Adsorption; Animals; Carbon; Cell Movement; Epithelial Cells; Fibrosis; Immunohistochemistry; Indican; Kidney; Kidney Failure, Chronic; Male; Membrane Proteins; Oxides; Phosphoproteins; Rats; Rats, Sprague-Dawley; Zonula Occludens-1 Protein | 2012 |
In vivo kinetics of indoxyl sulfate in humans and its renal interaction with angiotensin-converting enzyme inhibitor quinapril in rats.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Indican; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Male; Organic Anion Transporters, Sodium-Independent; Probenecid; Quinapril; Rats; Tetrahydroisoquinolines; Toxins, Biological; Young Adult | 2012 |
Uremic toxins induce kidney fibrosis by activating intrarenal renin-angiotensin-aldosterone system associated epithelial-to-mesenchymal transition.
Topics: Angiotensinogen; Animals; Cresols; Epithelial-Mesenchymal Transition; Fibrosis; Gene Expression Regulation; Indican; Kidney; Kidney Failure, Chronic; Kidney Tubules; Losartan; Male; Mice; Models, Biological; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Snail Family Transcription Factors; Sulfuric Acid Esters; Transcription Factors; Transforming Growth Factor beta1; Uremia | 2012 |
Serum total p-cresol and indoxyl sulfate correlated with stage of chronic kidney disease in renal transplant recipients.
Topics: Adult; Cresols; Disease Progression; Female; Humans; Indican; Kidney Failure, Chronic; Kidney Transplantation; Male | 2012 |
Interaction between two sulfate-conjugated uremic toxins, p-cresyl sulfate and indoxyl sulfate, during binding with human serum albumin.
Topics: Binding Sites; Biological Transport; Cresols; Humans; Immunotoxins; Indican; Kidney Failure, Chronic; Mutation; Protein Binding; Serum Albumin; Sulfates; Sulfuric Acid Esters; Ultrafiltration; Uremia | 2012 |
Indoxyl sulfate predicts cardiovascular disease and renal function deterioration in advanced chronic kidney disease.
Topics: Adult; Biomarkers; Cardiovascular Diseases; Female; Humans; Indican; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Multivariate Analysis | 2012 |
Uremic serum and solutes increase post-vascular interventional thrombotic risk through altered stability of smooth muscle cell tissue factor.
Topics: Adult; Aged; Cell Line; Coronary Vessels; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Male; Middle Aged; Myocytes, Smooth Muscle; Renal Dialysis; Risk Factors; Serum; Stents; Thromboplastin; Thrombosis; Ubiquitination; Uremia | 2013 |
Albumin is the main plasma binding protein for indoxyl sulfate and p-cresyl sulfate.
Topics: Binding Sites; Cresols; Humans; Indican; Kidney Failure, Chronic; Models, Biological; Protein Binding; Renal Dialysis; Serum Albumin; Sulfuric Acid Esters; Ultrafiltration | 2013 |
Effects of the oral adsorbent AST-120 on tryptophan metabolism in uremic patients.
Topics: Administration, Oral; Adsorption; Blood Proteins; Carbon; Dialysis; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Indican; Kidney Failure, Chronic; Microspheres; Middle Aged; Nutrition Disorders; Nutritional Status; Oxides; Protein Binding; Serum Albumin, Bovine; Tryptophan; Uremia | 2003 |
Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-kappaB and free radical in proximal tubular cells.
Topics: Anions; Cells, Cultured; Free Radicals; Gene Expression; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Kidney Tubules, Proximal; NF-kappa B; Oxidative Stress; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Signal Transduction; Toxins, Biological; Up-Regulation; Uremia | 2003 |
Pharmacokinetics and tissue distribution of uraemic indoxyl sulphate in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; In Vitro Techniques; Indican; Infusions, Intravenous; Kidney; Kidney Failure, Chronic; Male; Nephrectomy; Rats; Rats, Wistar; Tissue Distribution | 2003 |
Hormonal replacement therapy in an animal model with chronic renal failure and gonadectomy: biochemical and hematological study.
Topics: Animals; Creatinine; Disease Models, Animal; Erythrocyte Count; Estradiol; Female; Hematocrit; Hemoglobins; Indican; Kidney Failure, Chronic; Male; Nephrectomy; Orchiectomy; Ovariectomy; Random Allocation; Rats; Rats, Wistar; Testosterone; Urea | 2006 |
Accumulation of indoxyl sulfate in OAT1/3-positive tubular cells in kidneys of patients with chronic renal failure.
Topics: Aged; Aged, 80 and over; Female; Humans; Immunohistochemistry; Indican; Kidney; Kidney Failure, Chronic; Kidney Tubules; Kidney Tubules, Distal; Kidney Tubules, Proximal; Loop of Henle; Male; Middle Aged; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent | 2006 |
An oral adsorbent, AST-120 protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure.
Topics: Administration, Oral; Animals; Antioxidants; Biomarkers; Carbon; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression; Humans; Indican; Kidney Failure, Chronic; Male; Nephrectomy; Organic Anion Transport Protein 1; Oxidation-Reduction; Oxidative Stress; Oxides; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Serum Albumin; Time Factors; Transforming Growth Factor beta1 | 2007 |
Oral sorbent AST-120 increases renal NO synthesis in uremic rats.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Carbon; Creatinine; Disease Models, Animal; Indican; Kidney; Kidney Failure, Chronic; Male; Nephrectomy; Nitric Oxide; Nitric Oxide Synthase Type III; Oxides; Rats; Rats, Sprague-Dawley; Reference Values; Uremia | 2008 |
Indoxyl sulfate reduces superoxide scavenging activity in the kidneys of normal and uremic rats.
Topics: Animals; Case-Control Studies; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Half-Life; Immunohistochemistry; Indican; Kidney; Kidney Failure, Chronic; Pyrrolidines; Rats; Rats, Wistar; Superoxide Dismutase; Superoxides; Uremia | 2008 |
Relationship of impaired olfactory function in ESRD to malnutrition and retained uremic molecules.
Topics: Adult; Age Distribution; Ambulatory Care; Analysis of Variance; Cross-Sectional Studies; Ethylamines; Female; Follow-Up Studies; Hemodialysis Units, Hospital; Humans; Incidence; Indican; Kidney Failure, Chronic; Kidney Function Tests; Male; Malnutrition; Middle Aged; Nutritional Status; Olfaction Disorders; Probability; Renal Dialysis; Risk Assessment; Severity of Illness Index; Sex Distribution | 2008 |
A furan fatty acid and indoxyl sulfate are the putative inhibitors of thyroxine hepatocyte transport in uremia.
Topics: Adsorption; Animals; Biological Transport; Cells, Cultured; Furans; Hippurates; Humans; Indican; Iodides; Kidney Failure, Chronic; Liver; Male; Propionates; Rats; Rats, Wistar; Renal Dialysis; Thyroxine; Uremia | 1993 |
Indoxyl-beta-D-glucuronide and 3-indoxyl sulfate in plasma of hemodialysis patients.
Topics: beta 2-Microglobulin; Chromatography, High Pressure Liquid; Female; Fluorometry; Glucuronates; Humans; Indican; Indoles; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis | 1996 |
The protein metabolite hypothesis, a model for the progression of renal failure: an oral adsorbent lowers indoxyl sulfate levels in undialyzed uremic patients.
Topics: Administration, Oral; Adsorption; Aged; Carbon; Creatinine; Female; Humans; Indican; Kidney Failure, Chronic; Male; Microspheres; Middle Aged; Oxides; Uremia | 1997 |
Indoxyl sulfate stimulates renal synthesis of transforming growth factor-beta 1 and progression of renal failure.
Topics: Animals; Cells, Cultured; Disease Progression; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Indican; Intercellular Adhesion Molecule-1; Kidney; Kidney Failure, Chronic; Rats; RNA, Messenger; Swine; Transforming Growth Factor beta | 1997 |
Serum substances that interfere with thyroid hormone assays in patients with chronic renal failure.
Topics: Aged; Chromatography, High Pressure Liquid; Female; Hippurates; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Male; Middle Aged; Radioimmunoassay; Radioligand Assay; Regression Analysis; Renal Dialysis; Sensitivity and Specificity; Thyroid Hormones; Thyroxine; Triiodothyronine | 1998 |
Decreased bilirubin-binding capacity in uremic serum caused by an accumulation of furan dicarboxylic acid.
Topics: Adult; Bilirubin; Furans; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Propionates; Protein Binding; Serum Albumin; Uremia | 2000 |
An oral adsorbent ameliorates renal overload of indoxyl sulfate and progression of renal failure in diabetic rats.
Topics: Administration, Oral; Animals; Blood Urea Nitrogen; Carbon; Cholesterol; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Immunohistochemistry; Indican; Kidney; Kidney Failure, Chronic; Kidney Glomerulus; Male; Oxides; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Treatment Outcome; Triglycerides | 2001 |
The protein metabolite theory as a mechanism for the progression of renal failure.
Topics: Carbon; Dietary Proteins; Disease Progression; Humans; Indican; Kidney Failure, Chronic; Oxides; Uremia | 2001 |
Contributions of hippurate, indoxyl sulfate, and o-hydroxyhippurate to impaired ligand binding by plasma in azotemic humans.
Topics: Blood Proteins; Calcium; Chlorides; Creatinine; Hippurates; Humans; Indican; Kidney Failure, Chronic; Ligands; Salicylates; Salicylic Acid; Uremia | 1987 |
Diagnosis of uraemia post mortem.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Autopsy; Blood Chemical Analysis; Cerebrospinal Fluid; Child; Child, Preschool; Creatinine; Female; Humans; Indican; Infant; Kidney Failure, Chronic; Male; Middle Aged; Postmortem Changes; Sulfates; Urea; Uremia; Urine | 1969 |
A perspective on uremic toxins.
Topics: Ammonia; Animals; Blood Urea Nitrogen; Creatinine; Diet Therapy; Guanidines; Humans; Indican; Kidney Failure, Chronic; Phenols; Renal Dialysis; Sodium; Toxins, Biological; Urea; Uremia; Water-Electrolyte Balance | 1970 |