indican has been researched along with Kidney Diseases in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (15.79) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (18.42) | 29.6817 |
| 2010's | 23 (60.53) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Arimura, N; Fujita, I; Fukagawa, M; Imafuku, T; Maeda, H; Maruyama, T; Matsushita, K; Nakano, T; Tanaka, M; Tokumaru, K; Watanabe, H | 1 |
| Chen, J; Lv, J; Wang, M; Yan, F | 1 |
| Nolin, TD; Prokopienko, AJ | 1 |
| Huang, L; Ji, C; Lu, Z; Luo, Y; Tian, R; Zou, C | 1 |
| Asakura, M; Asano, Y; Asanuma, H; Chung, H; Fukuda, H; Funayama, M; Ihara, M; Imazu, M; Ito, S; Kitakaze, M; Min, KD; Minamino, T; Morita, T; Ogai, A; Sugimachi, M; Takahama, H; Takashima, S | 1 |
| Ayajiki, K; Ito, S; Jun-Ichi, S; Kobuchi, S; Manabe, E; Masuyama, T; Ohno, Y; Tanaka, T; Tsujino, T | 1 |
| Cai, GY; Chen, XM; Li, P; Liu, JQ; Song, YH; Sun, XF; Wang, SY; Wang, WJ | 1 |
| Nolin, TD; Prokopienko, AJ; Stubbs, JR; West, RE | 1 |
| Aronov, PA; Hostetter, TH; Meyer, TW; Plummer, NS; Sirich, TL | 1 |
| Brunet, P; Gondouin, B; Meyer, TW; Niwa, T; Sirich, TL | 1 |
| Barrios, C; Beaumont, M; Bell, JT; Clark, A; Goodrich, JK; Ley, RE; Menni, C; Pallister, T; Pascual, J; Spector, TD; Villar, J | 1 |
| Chen, M; Dong, M; Du, Y; Gao, H; Ji, J; Liao, S; Zhao, L; Zheng, H; Zhou, Q | 1 |
| Leong, SC; Sirich, TL | 1 |
| Aoyagi, M; Inaba, N; Kanda, E; Maeda, Y; Shiigai, T; Tanase, T; Tomura, S | 1 |
| Bammens, B; de Loor, H; Dehaen, W; Evenepoel, P; Meijers, BK; Meyer, TW; Verbeke, K | 1 |
| Aparicio, M; Chauveau, P; Fouque, D | 1 |
| Barreto, DV; Barreto, FC; Choukroun, G; Glorieux, G; Liabeuf, S; Massy, ZA; Meert, N; Temmar, M; Vanholder, R | 1 |
| Fujinaga, S; Hara, S; Ohtomo, Y; Shimizu, T; Someya, T; Umino, D | 1 |
| Fujita, T; Inagi, R; Kawakami, T; Nangaku, M; Tanaka, T; Wada, T | 1 |
| Kojima, T; Morimoto, A; Morita, T; Namba, S; Okuda, Y | 1 |
| Niwa, T | 2 |
| Kang, DH; Kim, YJ; Yu, M | 1 |
| Hostetter, TH; Li, Y; Luo, FY; Marquez, IO; Meyer, TW; Plummer, NS; Tambra, S | 1 |
| Meyer, TW; Sirich, T | 1 |
| Evenepoel, P; Meijers, BK | 1 |
| Fujii, H; Fukagawa, M; Nakai, K | 1 |
| Maruyama, T; Miyamoto, Y; Otagiri, M; Watanabe, H | 1 |
| Argiles, A; Cohen, G; De Smet, R; Duranton, F; Jankowski, J; Rodriguez, M; Vanholder, R | 1 |
| KASANEN, A | 1 |
| REDDY, V; SRIKANTIA, SG; VENKATACHALAM, PS | 1 |
| KUHLBAECK, B; PASTERNACK, A; TALLGREN, LG | 2 |
| DRUMMOND, KN; GOOD, RA; MICHAEL, AF; ULSTROM, RA | 1 |
| Niwa, T; Taki, K | 1 |
| Aoyama, I; Niwa, T; Shimokata, K | 1 |
| Aoyama, I; Cha, SH; Endou, H; Enomoto, A; Khamdang, S; Nakamura, S; Niwa, T; Sekine, T; Takayama, F; Takeda, M; Tojo, A | 1 |
| Müting, D | 1 |
4 review(s) available for indican and Kidney Diseases
| Article | Year |
|---|---|
Microbiota-derived uremic retention solutes: perpetrators of altered nonrenal drug clearance in kidney disease.
Topics: Animals; Cresols; Drug-Related Side Effects and Adverse Reactions; Dysbiosis; Gastrointestinal Microbiome; Humans; Indican; Kidney Diseases; Liver; Pharmaceutical Preparations; Sulfuric Acid Esters; Toxins, Biological | 2018 |
Indoxyl Sulfate-Review of Toxicity and Therapeutic Strategies.
Topics: Animals; Bone Diseases; Humans; Indican; Kidney Diseases; Vascular Diseases | 2016 |
Indoxyl sulfate is a nephro-vascular toxin.
Topics: Adsorption; Animals; Carbon; Cardiovascular Diseases; Free Radicals; Glomerular Mesangium; Humans; Indican; Kidney Diseases; Kidney Tubules; Models, Biological; Oxidative Stress; Oxides; Proteins; Uremia | 2010 |
Normal and pathologic concentrations of uremic toxins.
Topics: beta 2-Microglobulin; Chronic Disease; Homocysteine; Humans; Indican; Kidney Diseases; Parathyroid Hormone; Toxins, Biological; Uremia; Uric Acid | 2012 |
1 trial(s) available for indican and Kidney Diseases
| Article | Year |
|---|---|
[Examination of activated charcoal preparations in chronic kidney disease: comparing Kremezin (K) and Merckmezin (M)].
Topics: Adult; Aged; Biomarkers; Carbon; Chronic Disease; Creatinine; Drugs, Generic; Female; Humans; Indican; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged; Oxides; Prospective Studies | 2009 |
33 other study(ies) available for indican and Kidney Diseases
| Article | Year |
|---|---|
Indoxyl Sulfate Contributes to mTORC1-Induced Renal Fibrosis via The OAT/NADPH Oxidase/ROS Pathway.
Topics: Cell Line; Epithelial Cells; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Indican; Kidney Diseases; Kidney Tubules; Macrophages; Mechanistic Target of Rapamycin Complex 1; NADPH Oxidases; Ornithine-Oxo-Acid Transaminase; Reactive Oxygen Species; Signal Transduction | 2021 |
Klotho alleviates indoxyl sulfate-induced heart failure and kidney damage by promoting M2 macrophage polarization.
Topics: Animals; Cell Line, Tumor; Glucuronidase; Heart Failure; Humans; Indican; Kidney Diseases; Klotho Proteins; Macrophages; Mice; Mice, Inbred C57BL | 2020 |
Effect of astragaloside IV on indoxyl sulfate-induced kidney injury in mice via attenuation of oxidative stress.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Deoxyguanosine; Indican; Interleukin-1beta; Interleukin-6; Kidney; Kidney Diseases; Male; Malondialdehyde; Mice, Inbred C57BL; Oxidative Stress; Saponins; Superoxide Dismutase; Triterpenes | 2018 |
AST-120, an Adsorbent of Uremic Toxins, Improves the Pathophysiology of Heart Failure in Conscious Dogs.
Topics: Adsorption; Animals; Apoptosis; Apoptosis Regulatory Proteins; Carbon; Cardio-Renal Syndrome; Consciousness; Disease Models, Animal; Dogs; Fibrosis; Heart Failure; Hemodynamics; Indican; Kidney Diseases; Mitochondria, Heart; Myocardium; Oxides; Signal Transduction; Sorption Detoxification; Uremia; Ventricular Function, Left | 2019 |
Neutrophil/lymphocyte ratio elevation in renal dysfunction is caused by distortion of leukocyte hematopoiesis in bone marrow.
Topics: Adenine; Aged; Aged, 80 and over; Animals; Biomarkers; Bone Marrow; Carbon; Cardiovascular Diseases; Disease Models, Animal; Female; Glomerular Filtration Rate; Hematopoiesis; Humans; Indican; Kidney Diseases; Lymphocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Middle Aged; Neutrophils; Oxides; Prognosis; Retrospective Studies; Risk Factors | 2019 |
Methionine restriction delays senescence and suppresses the senescence-associated secretory phenotype in the kidney through endogenous hydrogen sulfide.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Caloric Restriction; Cell Line; Cellular Senescence; Cystathionine gamma-Lyase; Cytokines; Humans; Hydrogen Sulfide; Indican; Kidney; Kidney Diseases; Longevity; Male; Methionine; Mice; Mice, Inbred C57BL; Phosphorylation; TOR Serine-Threonine Kinases | 2019 |
Development and validation of a UHPLC-MS/MS method for measurement of a gut-derived uremic toxin panel in human serum: An application in patients with kidney disease.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cresols; Hippurates; Humans; Hydrogen-Ion Concentration; Indican; Kidney Diseases; Kynurenic Acid; Quality Control; Reproducibility of Results; Risk Factors; Solvents; Sulfuric Acid Esters; Tandem Mass Spectrometry; Time Factors; Uremia | 2019 |
Numerous protein-bound solutes are cleared by the kidney with high efficiency.
Topics: Adult; Aged; Aged, 80 and over; Chromatography, Liquid; Cresols; Female; Hippurates; Humans; Indican; Kidney; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged; Protein Binding; Renal Dialysis; Sulfuric Acid Esters; Tandem Mass Spectrometry | 2013 |
Protein-bound molecules: a large family with a bad character.
Topics: Cardiovascular Diseases; Cognition Disorders; Cresols; Humans; Indican; Kidney Diseases; Protein Binding; Sulfuric Acid Esters | 2014 |
Gut-Microbiota-Metabolite Axis in Early Renal Function Decline.
Topics: Adult; Aged; Aged, 80 and over; Body Mass Index; Clostridiales; Cresols; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diseases in Twins; Feces; Female; Fermentation; Gastrointestinal Microbiome; Glomerular Filtration Rate; Glutamine; Humans; Indican; Kidney Diseases; Male; Metabolome; Microbiota; Middle Aged; Ribotyping; Sulfuric Acid Esters | 2015 |
Identification of key metabolic changes in renal interstitial fibrosis rats using metabonomics and pharmacology.
Topics: Amino Acids, Branched-Chain; Animals; Biomarkers; Disease Models, Animal; Indican; Kidney; Kidney Diseases; Male; Metabolomics; Proton Magnetic Resonance Spectroscopy; Rats; Rats, Sprague-Dawley; Urine | 2016 |
Sodium octanoate to reverse indoxyl sulfate and p-cresyl sulfate albumin binding in uremic and normal serum during sample preparation followed by fluorescence liquid chromatography.
Topics: Albumins; Caprylates; Chromatography, Liquid; Cresols; Fluorescence; Humans; Indican; Kidney Diseases; Protein Binding; Sensitivity and Specificity; Sulfuric Acid Esters | 2009 |
Effect of a very low-protein diet on long-term outcomes.
Topics: Chronic Disease; Diet, Protein-Restricted; Humans; Indican; Kidney Diseases; Prognosis; Treatment Outcome; Tryptophan | 2009 |
Serum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients.
Topics: Adult; Aged; Chronic Disease; Female; Glomerular Filtration Rate; Humans; Indican; Kidney Diseases; Male; Middle Aged; Parathyroid Hormone; Proportional Hazards Models; Vascular Diseases | 2009 |
Serum indoxyl sulfate as an early marker for detecting chronic cyclosporine nephrotoxicity.
Topics: Adolescent; Biomarkers; Child; Child, Preschool; Chronic Disease; Cyclosporine; Early Diagnosis; Female; Humans; Immunosuppressive Agents; Indican; Kidney Diseases; Male; Young Adult | 2010 |
Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress.
Topics: Animals; Carbon; Cell Death; Cell Line; Cell Proliferation; Chronic Disease; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Endoplasmic Reticulum; Extracellular Signal-Regulated MAP Kinases; Humans; Indican; Interleukin-6; Kidney Diseases; Kidney Tubules, Proximal; Male; Nephrectomy; Oxides; Rats; Rats, Sprague-Dawley; Signal Transduction; Stress, Physiological; Transcription Factor CHOP | 2010 |
[Serum indoxyl sulfate is a useful predictor for progression of chronic kidney disease].
Topics: Aged; Biomarkers; Chronic Disease; Disease Progression; Female; Humans; Indican; Kidney Diseases; Male; Middle Aged; Predictive Value of Tests | 2010 |
Indoxyl sulfate-induced endothelial dysfunction in patients with chronic kidney disease via an induction of oxidative stress.
Topics: Adult; Carbon; Cells, Cultured; Chronic Disease; Endothelial Cells; Female; Humans; Indican; Kidney Diseases; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Oxides; Prospective Studies | 2011 |
Contribution of residual function to removal of protein-bound solutes in hemodialysis.
Topics: Adult; Aged; Cresols; Female; Glomerular Filtration Rate; Hippurates; Humans; Indican; Kidney; Kidney Diseases; Linear Models; Male; Middle Aged; Models, Biological; Practice Guidelines as Topic; Protein Binding; Renal Dialysis; Sulfuric Acid Esters; Time Factors; Treatment Outcome; Urea | 2011 |
Indoxyl sulfate: long suspected but not yet proven guilty.
Topics: Carbon; Chronic Disease; Endothelial Cells; Glomerular Filtration Rate; Humans; Indican; Kidney Diseases; Oxides; Vascular Diseases | 2011 |
The gut-kidney axis: indoxyl sulfate, p-cresyl sulfate and CKD progression.
Topics: Chronic Disease; Cresols; Disease Progression; Humans; Indican; Kidney Diseases; Sulfuric Acid Esters | 2011 |
Role of oxidative stress and indoxyl sulfate in progression of cardiovascular disease in chronic kidney disease.
Topics: Animals; Carbon; Cardiovascular Diseases; Chronic Disease; Disease Progression; Drug Delivery Systems; Humans; Indican; Kidney Diseases; Oxidative Stress; Oxides; Uremia | 2011 |
New insight into the redox properties of uremic solute indoxyl sulfate as a pro- and anti-oxidant.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Chronic Disease; Humans; Indican; Kidney Diseases; Oxidants; Oxidation-Reduction; Oxidative Stress; Uremia | 2011 |
Role of indoxyl sulfate in the progression of chronic kidney disease and cardiovascular disease: experimental and clinical effects of oral sorbent AST-120.
Topics: Animals; Carbon; Cardiovascular Diseases; Chronic Disease; Disease Progression; Humans; Indican; Kidney Diseases; Oxidative Stress; Oxides; Protein Binding; Rats; Uremia | 2011 |
Serum indican and endogenous indican clearance in renal insufficiency.
Topics: Humans; Indican; Kidney; Kidney Diseases; Renal Insufficiency | 1957 |
CLINICAL AND BIOCHEMICAL FEATURES OF A CASE OF HARTNUP DISEASE.
Topics: Biochemical Phenomena; Biochemistry; Child; Genetics, Medical; Hartnup Disease; Humans; Indican; Indoleacetic Acids; Kidney; Kidney Diseases; Pellagra; Renal Aminoacidurias; Tryptophan; Urine | 1964 |
SERUM INDICAN IN HAEMODIALYSIS.
Topics: Blood Chemical Analysis; Creatine; Creatinine; Indican; Kidney; Kidney Diseases; Kidney Function Tests; Kidneys, Artificial; Renal Dialysis; Statistics as Topic | 1964 |
THE BLUE DIAPER SYNDROME: FAMILIAL HYPERCALCEMIA WITH NEPHROCALCINOSIS AND INDICANURIA; A NEW FAMILIAL DISEASE, WITH DEFINITION OF THE METABOLIC ABNORMALITY.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Blood Protein Electrophoresis; Chromatography; Electrophoresis; Eye Abnormalities; Humans; Hypercalcemia; Indican; Indoles; Intestinal Absorption; Kidney Diseases; Kidney Function Tests; Lipid Metabolism; Metabolism, Inborn Errors; Nephrocalcinosis; Pathology; Radiography; Spectrophotometry; Tryptophan; Urine; Vitamins | 1964 |
SERUM INDICAN IN RENAL DISEASE.
Topics: Blood; Creatine; Creatinine; Glomerulonephritis; Indican; Kidney Diseases; Nephrotic Syndrome; Urea; Uric Acid | 1964 |
Indoxyl sulfate-lowering capacity of oral sorbents affects the prognosis of kidney function and oxidative stress in chronic kidney disease.
Topics: Acrolein; Administration, Oral; Adsorption; Animals; Biomarkers; Carbon; Chronic Disease; Creatinine; Disease Progression; Gastrointestinal Agents; Indican; Kidney Diseases; Male; Oxidative Stress; Oxides; Prognosis; Rats; Rats, Sprague-Dawley | 2007 |
Combination therapy with benazepril and oral adsorbent ameliorates progressive renal fibrosis in uremic rats.
Topics: Adsorption; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Blood Pressure; Carbon; Cells, Cultured; Disease Progression; Drug Therapy, Combination; Fibroblasts; Fibrosis; Humans; In Situ Hybridization; Indican; Kidney; Kidney Diseases; Male; Nephrectomy; Nephrosclerosis; Osteopontin; Oxides; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Transforming Growth Factor beta1; Uremia | 2002 |
Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity.
Topics: Animals; Anions; Biological Transport; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Immunohistochemistry; Indican; Kidney Cortex; Kidney Diseases; Kidney Tubules; Kidney Tubules, Proximal; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Osmolar Concentration; Probenecid; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2002 |
Studies on the pathogenesis of uremia. Comparative determinations of glucuronic acid, indican, free and bound phenols in the serum, cerebrospinal fluid, and urine of renal diseases with and without uremia.
Topics: Blood Chemical Analysis; Cerebrospinal Fluid; Chemistry, Clinical; Coma; Glucuronates; Humans; Indican; Kidney Diseases; Phenols; Uremia; Urine | 1965 |