Page last updated: 2024-08-21

indican and Inflammation

indican has been researched along with Inflammation in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's21 (51.22)24.3611
2020's20 (48.78)2.80

Authors

AuthorsStudies
Cetinkaya, MA; Kepekci-Tekkeli, SE; Kul, O; Melekoglu, E; Samur, G1
Eiam-Ong, S; Katavetin, P; Leelahavanichkul, A; Panpetch, W; Praditpornsilpa, K; Saisorn, W; Tumwasorn, S; Tungsanga, K; Tungsanga, S; Udompornpitak, K1
Hosoda, Y; Miyazaki, M; Mori, T; Sato, E; Sato, H; Sekimoto, A; Takahashi, N; Todoriki, S; Watanabe, M; Yamamoto, T1
Dimković, N; Golić, N; Mitrović, M; Nastasijević, B; Soković Bajić, S; Soldatović, I; Stanković-Popović, V; Svorcan, P; Tolinački, M; Veljović, K1
Garssen, J; Madella, AM; Masereeuw, R; Overbeek, SA; Van Bergenhenegouwen, J1
Salminen, A1
Alvarenga, L; Fouque, D; Mafra, D; Saldanha, JF; Soulage, CO; Stockler-Pinto, MB1
Adamowicz, K; Anders, HJ; Koziel, J; Lech, M; Liu, F; Ribeiro, A; Rother, S; Schmaderer, C; Srebrzynski, M; Steiger, S; Wadowska, M1
Abate, M; Capasso, A; Capasso, G; Caraglia, M; De, A; Di Paola, R; Izhar, R; La Russa, A; Perna, AF; Simeoni, M; Zappavigna, S1
Chang, L; Guo, Z; He, L; Li, Y; Tian, R; Xu, Y; Zhang, H1
Horikawa, M; Hou, H; Izumi, Y; Jono, H; Kakizoe, Y; Kuwabara, T; Mukoyama, M; Narita, Y; Saito, H1
Gao, LW; Hu, G; Jian, WX; Tian, Z; Tong, KK; Yang, XY; Yin, S; Yu, YF1
Atapour, A; Entezari, MH; Feizi, A; Hekmatdoost, A; Mirzaeian, S; Saraf-Bank, S1
Azevedo, R; Brito, JS; Cardozo, LFMF; Cunha, DB; Esgalhado, M; Kemp, JA; Mafra, D; Nakao, LS; Paiva, BR1
Burtey, S; Corbeau, P; Cristol, JP; Dunyach-Remy, C; Lavigne, JP; Moranne, O; Olivier, V; Sutra, T1
Arimura, N; Enoki, Y; Fukagawa, M; Imafuku, T; Kato, H; Maeda, H; Maruyama, T; Matsushita, K; Nakano, T; Tanaka, M; Tanaka, S; Tokumaru, K; Watanabe, H1
Alaniz, RC; Eshghjoo, S; Jayaraman, A; Sun, Y1
Autore, G; Dal Piaz, F; Di Iorio, BR; Iovane, V; Marzocco, S; Nishijima, F; Paciello, O; Popolo, A; Prisco, F; Rapa, SF1
Cosola, C; Gesualdo, L; Ranieri, E; Rocchetti, MT1
Armelloni, S; Caldiroli, L; Callegari, ML; Margiotta, E; Messa, P; Miragoli, F; Rizzo, V; Vettoretti, S; Zanoni, F1
Murohara, T; Niwa, T; Saito, S; Takeshita, K; Yisireyili, M1
Li, DY; Tang, WHW1
Chillon, JM; Hénaut, L; Kamel, S; Massy, ZA1
Jerman, A; Osredkar, J; Pajek, J; Pajek, M; Ponikvar, JB1
Chen, HF; Chou, YH; Huang, HP; Hung, SC; Sheen, JF; Shen, WC1
Kaminski, TW; Karbowska, M; Mor, AL; Mysliwiec, M; Pawlak, D; Pawlak, K; Znorko, B1
Bi, X; Han, W; He, T; Huang, Y; Liu, C; Liu, Y; Xiao, T; Xiong, J; Xu, X; Yang, K; Yu, Y; Zhang, B; Zhang, J; Zhao, J; Zheng, C1
Armstrong, EJ; Granick, JL; Simon, SI1
Croze, M; Fouque, D; Mafra, D; Soulage, CO; Stockler-Pinto, MB1
Andersen, GL; DeSantis, TZ; Pahl, M; Piceno, YM; Vaziri, ND; Wong, J1
Campbell, KL; Coombes, JS; Hawley, CM; Isbel, N; Johnson, DW; McWhinney, BC; Rossi, M; Stanton, T; Ungerer, JP; Vesey, DA; Weston, KS1
Chen, CK; Chen, CY; Chou, CC; Hsu, HJ; Hsu, KH; Lee, CC; Sun, CY; Tsai, CJ; Wu, IW; Wu, MS; Yen, CH1
Choukroun, G; Desjardins, L; Kamel, S; Lemke, HD; Liabeuf, S; Louvet, L; Massy, ZA; Oliveira, RB; Vanholder, R1
Fouque, D; Mafra, D; Saldanha, JF; Soulage, CO; Stockler-Pinto, MB; Yi, D1
Liu, X; Lu, F; Lu, Z; Zeng, Y; Zou, C1
Alvarez, JI; Anandasabapathy, N; Antel, J; Blain, M; Bunse, L; Chao, CC; Clish, CB; Izquierdo, G; Jung, S; Kébir, H; Kenison, JE; Mascanfroni, ID; Mayo, L; Obholzer, N; Patel, B; Pochet, N; Prat, A; Prinz, M; Quintana, FJ; Rothhammer, V; Takenaka, MC; Yan, R1
Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA1
Kamiński, TW; Karbowska, M; Myśliwiec, M; Pawlak, D; Pawlak, K1
Hsu, HH; Sun, CY; Wu, MS1
Koizumi, M; Morita, T; Namba, S; Tatebe, J; Watanabe, I; Yamazaki, J1
Higuchi, Y; Ishii, H; Ito, S; Nishijima, F; Osaka, M; Yagi, Y; Yamato, H; Yoshida, M1

Reviews

8 review(s) available for indican and Inflammation

ArticleYear
Microbial-Derived Tryptophan Catabolites, Kidney Disease and Gut Inflammation.
    Toxins, 2022, 09-18, Volume: 14, Issue:9

    Topics: Fatty Acids, Volatile; Humans; Indican; Inflammation; Prebiotics; Pregnane X Receptor; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Tryptophan

2022
Activation of aryl hydrocarbon receptor (AhR) in Alzheimer's disease: role of tryptophan metabolites generated by gut host-microbiota.
    Journal of molecular medicine (Berlin, Germany), 2023, Volume: 101, Issue:3

    Topics: Alzheimer Disease; Dysbiosis; Gastrointestinal Microbiome; Humans; Indican; Indoles; Inflammation; Microbiota; Receptors, Aryl Hydrocarbon; Tryptophan

2023
Possible Effects of Uremic Toxins p-Cresol, Indoxyl Sulfate, p-Cresyl Sulfate on the Development and Progression of Colon Cancer in Patients with Chronic Renal Failure.
    Genes, 2023, 06-13, Volume: 14, Issue:6

    Topics: Colonic Neoplasms; Humans; Indican; Inflammation; Kidney Failure, Chronic; Renal Insufficiency, Chronic; Sulfates; Uremic Toxins

2023
Microbiota-Mediated Immune Regulation in Atherosclerosis.
    Molecules (Basel, Switzerland), 2021, Jan-01, Volume: 26, Issue:1

    Topics: Animals; Atherosclerosis; Basic Helix-Loop-Helix Transcription Factors; Foam Cells; Gastrointestinal Microbiome; Humans; Indican; Inflammation; Methylamines; Receptors, Aryl Hydrocarbon

2021
Protein-Bound Uremic Toxins and Immunity.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2325

    Topics: Adaptive Immunity; Cardiovascular Diseases; Cresols; Gastrointestinal Microbiome; Humans; Immunity, Innate; Indican; Inflammation; Renal Insufficiency, Chronic; Sulfuric Acid Esters; T-Lymphocytes; Toxins, Biological; Uremia

2021
Contributory Role of Gut Microbiota and Their Metabolites Toward Cardiovascular Complications in Chronic Kidney Disease.
    Seminars in nephrology, 2018, Volume: 38, Issue:2

    Topics: Animals; Cardiovascular Diseases; Cresols; Diet Therapy; Dietary Supplements; Dysbiosis; Enzyme Inhibitors; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Indican; Inflammation; Methylamines; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Toxins, Biological

2018
Updates on the Mechanisms and the Care of Cardiovascular Calcification in Chronic Kidney Disease.
    Seminars in nephrology, 2018, Volume: 38, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Calcimimetic Agents; Calcium; Cardiovascular Diseases; Chelating Agents; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Glucuronidase; Glycation End Products, Advanced; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indican; Inflammation; Klotho Proteins; Magnesium; Mesenchymal Stem Cells; Phosphates; Renal Insufficiency, Chronic; Tunica Intima; Tunica Media; Vascular Calcification; Vitamin K 2; Zinc Finger Protein GLI1

2018
Indoxyl sulfate and p-cresyl sulfate in chronic kidney disease. Could these toxins modulate the antioxidant Nrf2-Keap1 pathway?
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2014, Volume: 24, Issue:5

    Topics: Antioxidants; Cresols; Gene Expression Regulation; Humans; Indican; Inflammation; Intestines; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Microbiota; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Renal Insufficiency, Chronic; Signal Transduction; Sulfuric Acid Esters

2014

Trials

4 trial(s) available for indican and Inflammation

ArticleYear
The Impact of Synbiotic Treatment on the Levels of Gut-Derived Uremic Toxins, Inflammation, and Gut Microbiome of Chronic Kidney Disease Patients-A Randomized Trial.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2023, Volume: 33, Issue:2

    Topics: Adolescent; Adult; C-Reactive Protein; Gastrointestinal Microbiome; Humans; Indican; Inflammation; Renal Insufficiency, Chronic; Synbiotics; Uremic Toxins

2023
Low-protein diet supplemented with inulin lowers protein-bound toxin levels in patients with stage 3b-5 chronic kidney disease: a randomized controlled study.
    Nutricion hospitalaria, 2023, 08-28, Volume: 40, Issue:4

    Topics: Diet, Protein-Restricted; Dietary Proteins; Dietary Supplements; Humans; Indican; Inflammation; Inulin; Kidney Failure, Chronic; Renal Insufficiency, Chronic

2023
Effects of synbiotic supplementation on microbiota-derived protein-bound uremic toxins, systemic inflammation, and biochemical parameters in patients on hemodialysis: A double-blind, placebo-controlled, randomized clinical trial.
    Nutrition (Burbank, Los Angeles County, Calif.), 2020, Volume: 73

    Topics: Double-Blind Method; Humans; Indican; Inflammation; Microbiota; Renal Dialysis; Synbiotics

2020
Resistant starch type-2 enriched cookies modulate uremic toxins and inflammation in hemodialysis patients: a randomized, double-blind, crossover and placebo-controlled trial.
    Food & function, 2020, Mar-26, Volume: 11, Issue:3

    Topics: Administration, Oral; Biomarkers; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Gastrointestinal Microbiome; Humans; Indican; Inflammation; Middle Aged; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Renal Dialysis; Resistant Starch

2020

Other Studies

29 other study(ies) available for indican and Inflammation

ArticleYear
Effects of prebiotic oligofructose-enriched inulin on gut-derived uremic toxins and disease progression in rats with adenine-induced chronic kidney disease.
    PloS one, 2021, Volume: 16, Issue:10

    Topics: Adenine; Animals; Blood Urea Nitrogen; Cresols; Disease Models, Animal; Dysbiosis; Humans; Indican; Inflammation; Interleukin-6; Inulin; Oligosaccharides; Prebiotics; Rats; Reactive Oxygen Species; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Urea

2021
Lactobacillus rhamnosus L34 attenuates chronic kidney disease progression in a 5/6 nephrectomy mouse model through the excretion of anti-inflammatory molecules.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2022, 07-26, Volume: 37, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Caco-2 Cells; Culture Media, Conditioned; Disease Models, Animal; Fibrosis; Humans; Indican; Inflammation; Lacticaseibacillus rhamnosus; Mice; Nephrectomy; Renal Insufficiency, Chronic; Tumor Necrosis Factor-alpha

2022
Methylglyoxal Induces Inflammation, Metabolic Modulation and Oxidative Stress in Myoblast Cells.
    Toxins, 2022, 04-07, Volume: 14, Issue:4

    Topics: Adenosine Triphosphate; Animals; Female; Humans; Indican; Inflammation; Male; Mice; Muscular Atrophy; Myoblasts; Oxidative Stress; Pyruvaldehyde; Renal Insufficiency, Chronic; Sarcopenia

2022
Effects of resveratrol on inflammation and oxidative stress induced by the uremic toxin indoxyl sulfate in Murine macrophage-like RAW 264.7.
    Biochimie, 2023, Volume: 213

    Topics: Animals; Humans; Indican; Inflammation; Macrophages; Mice; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Uremic Toxins

2023
Uremic Toxin Indoxyl Sulfate Promotes Macrophage-Associated Low-Grade Inflammation and Epithelial Cell Senescence.
    International journal of molecular sciences, 2023, Apr-28, Volume: 24, Issue:9

    Topics: Epithelial Cells; Humans; Indican; Inflammation; Lipopolysaccharides; Macrophages; Reactive Oxygen Species; Uremic Toxins

2023
Suppression of Indoxyl Sulfate Accumulation Reduces Renal Fibrosis in Sulfotransferase 1a1-Deficient Mice.
    International journal of molecular sciences, 2023, Jul-11, Volume: 24, Issue:14

    Topics: Animals; Disease Models, Animal; Erythropoietin; Fibrosis; Humans; Indican; Inflammation; Kidney; Mice; Mice, Inbred C57BL; Renal Insufficiency, Chronic; Sulfotransferases; Ureteral Obstruction

2023
Bibliometric analysis of intestinal microbiota in diabetic nephropathy.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:18

    Topics: Bibliometrics; Diabetes Mellitus; Diabetic Nephropathies; Drugs, Chinese Herbal; Gastrointestinal Microbiome; Humans; Indican; Inflammation; Obesity

2023
Factors of microinflammation in non-diabetic chronic kidney disease: a pilot study.
    BMC nephrology, 2020, 04-21, Volume: 21, Issue:1

    Topics: Bacterial Translocation; Biomarkers; C-Reactive Protein; Female; Gastrointestinal Microbiome; Humans; Indican; Indoleacetic Acids; Inflammation; Kidney Function Tests; Male; Oxidative Stress; Patient Acuity; Pilot Projects; Renal Dialysis; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Uremia

2020
Indoxyl Sulfate Contributes to Adipose Tissue Inflammation through the Activation of NADPH Oxidase.
    Toxins, 2020, 08-05, Volume: 12, Issue:8

    Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Anti-Inflammatory Agents; Calcium-Binding Proteins; Carbon; Chemokine CCL2; Indican; Inflammation; Male; Mice; Mice, Inbred ICR; NADPH Oxidases; Oxidative Stress; Oxides; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Renal Insufficiency, Chronic; Tumor Necrosis Factor-alpha

2020
Pro-Inflammatory Effects of Indoxyl Sulfate in Mice: Impairment of Intestinal Homeostasis and Immune Response.
    International journal of molecular sciences, 2021, Jan-24, Volume: 22, Issue:3

    Topics: Animals; bcl-2-Associated X Protein; Cyclooxygenase 2; Gene Expression Regulation; Indican; Inflammation; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Oxidative Stress; Renal Insufficiency, Chronic; Tumor Necrosis Factor-alpha; Tyrosine

2021
Association of Sarcopenia and Gut Microbiota Composition in Older Patients with Advanced Chronic Kidney Disease, Investigation of the Interactions with Uremic Toxins, Inflammation and Oxidative Stress.
    Toxins, 2021, 07-08, Volume: 13, Issue:7

    Topics: Aged; Bacteria; Gastrointestinal Microbiome; Humans; Indican; Inflammation; Interleukin-6; Malondialdehyde; Middle Aged; Oxidative Stress; Renal Dialysis; Renal Insufficiency, Chronic; Sarcopenia; Uremia; Uremic Toxins

2021
Indole-3-propionic acid suppresses indoxyl sulfate-induced expression of fibrotic and inflammatory genes in proximal tubular cells.
    Nagoya journal of medical science, 2017, Volume: 79, Issue:4

    Topics: Animals; Blotting, Western; Cell Line; Chemokine CCL2; Cytochrome P-450 CYP1A1; Humans; Immunohistochemistry; Indican; Inflammation; Kidney Tubules, Proximal; Propionates; Rats; Receptors, Aryl Hydrocarbon; STAT3 Transcription Factor; Transforming Growth Factor beta1

2017
Association of Uremic Toxins and Inflammatory Markers with Physical Performance in Dialysis Patients.
    Toxins, 2018, 10-01, Volume: 10, Issue:10

    Topics: Adult; Aged; Arginine; beta 2-Microglobulin; Biomarkers; C-Reactive Protein; Female; Hand Strength; Humans; Indican; Inflammation; Insulin-Like Growth Factor I; Interleukin-6; Male; Middle Aged; Myostatin; Physical Functional Performance; Renal Dialysis; Toxins, Biological; Urea; Uremia; Walking

2018
Induced pluripotent stem cell-derived endothelial progenitor cells attenuate ischemic acute kidney injury and cardiac dysfunction.
    Stem cell research & therapy, 2018, 12-10, Volume: 9, Issue:1

    Topics: Acute Kidney Injury; Animals; Apoptosis; Azotemia; Capillaries; Creatinine; Endothelial Progenitor Cells; Heart; Humans; Indican; Induced Pluripotent Stem Cells; Inflammation; Interleukin-1beta; Ischemia; Kidney Tubules; Male; Mice, Inbred NOD; Mice, SCID; Myocytes, Cardiac; Neovascularization, Physiologic

2018
The impact of antihypertensive pharmacotherapy on interplay between protein-bound uremic toxin (indoxyl sulfate) and markers of inflammation in patients with chronic kidney disease.
    International urology and nephrology, 2019, Volume: 51, Issue:3

    Topics: Adult; Aged; Antibodies; Antihypertensive Agents; Biomarkers; Blood Pressure; C-Reactive Protein; Creatinine; Drug Therapy, Combination; E-Selectin; Female; Ferritins; Humans; Hypertension; Indican; Inflammation; Interleukin-6; Lipoproteins, LDL; Lymphocyte Count; Male; Middle Aged; Neopterin; Neutrophils; Oxidative Stress; P-Selectin; Renal Insufficiency, Chronic; Superoxide Dismutase-1; Tumor Necrosis Factor-alpha

2019
Klotho restrain RIG-1/NF-κB signaling activation and monocyte inflammatory factor release under uremic condition.
    Life sciences, 2019, Aug-15, Volume: 231

    Topics: Adult; Animals; Blotting, Western; DEAD Box Protein 58; Female; Glucuronidase; Humans; Indican; Inflammation; Interleukin-6; Kidney; Klotho Proteins; Male; Mice; Mice, Inbred BALB C; Middle Aged; Monocytes; NF-kappa B; Receptors, Immunologic; Renal Insufficiency, Chronic; Signal Transduction; THP-1 Cells; Tumor Necrosis Factor-alpha; Uremia

2019
Editorial: A missing link? Monocyte activation by uremic toxins in cardiorenal syndrome.
    Journal of leukocyte biology, 2013, Volume: 93, Issue:6

    Topics: Animals; Carbon; Gastrointestinal Agents; Humans; Indican; Inflammation; Male; Monocytes; Oxides; Renal Insufficiency, Chronic

2013
Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD.
    American journal of nephrology, 2014, Volume: 39, Issue:3

    Topics: Adult; Aged; Ammonia; Cresols; Diet; Fatty Acids, Volatile; Female; Humans; Indican; Indoles; Inflammation; Intestines; Kidney Failure, Chronic; Male; Microbiota; Middle Aged; Sulfuric Acid Esters; Urate Oxidase; Urea; Urease

2014
Protein-bound uremic toxins, inflammation and oxidative stress: a cross-sectional study in stage 3-4 chronic kidney disease.
    Archives of medical research, 2014, Volume: 45, Issue:4

    Topics: Aged; Antioxidants; Biomarkers; Blood Proteins; Cardiovascular Diseases; Cresols; Cross-Sectional Studies; Female; Humans; Indican; Inflammation; Interleukin-6; Male; Middle Aged; Oxidative Stress; Renal Insufficiency, Chronic; Risk Reduction Behavior; Sulfuric Acid Esters; Toxins, Biological; Uremia; Vascular Stiffness

2014
The association of uremic toxins and inflammation in hemodialysis patients.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Aged; Comorbidity; Coronary Artery Disease; Creatinine; Cresols; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Indican; Inflammation; Inflammation Mediators; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Sulfuric Acid Esters

2014
Uremic toxicity and sclerostin in chronic kidney disease patients.
    Nephrologie & therapeutique, 2014, Volume: 10, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aortography; Arteriosclerosis; beta 2-Microglobulin; Biomarkers; Bone Morphogenetic Proteins; Calcinosis; Cresols; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Follow-Up Studies; Genetic Markers; Humans; Indican; Inflammation; Male; Middle Aged; Pulse Wave Analysis; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Survival Analysis; Tomography, Spiral Computed; Uremia; Vascular Stiffness

2014
The uremic toxin indoxyl sulfate exacerbates reactive oxygen species production and inflammation in 3T3-L1 adipose cells.
    Free radical research, 2016, Volume: 50, Issue:3

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Indican; Inflammation; Interleukin-6; Mice; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Renal Insufficiency, Chronic; Toxins, Biological; Tumor Necrosis Factor-alpha; Uremia

2016
Rhubarb Enema Attenuates Renal Tubulointerstitial Fibrosis in 5/6 Nephrectomized Rats by Alleviating Indoxyl Sulfate Overload.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; C-Reactive Protein; Collagen Type I; Deoxyguanosine; Enema; Indican; Inflammation; Kidney; Male; Nephrectomy; NF-kappa B; Occludin; Oxidative Stress; Rats, Sprague-Dawley; Rheum; Superoxide Dismutase

2015
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.
    Nature medicine, 2016, Volume: 22, Issue:6

    Topics: Animals; Astrocytes; Case-Control Studies; Cell Proliferation; Central Nervous System; Chemokine CCL2; Chromatin Immunoprecipitation; Chromatography, High Pressure Liquid; Encephalomyelitis, Autoimmune, Experimental; Fluorescent Antibody Technique; Gastrointestinal Microbiome; Gene Expression Profiling; Gene Knockdown Techniques; Glial Fibrillary Acidic Protein; Humans; Immunoblotting; Indican; Indoles; Inflammation; Interferon Type I; Interferon-beta; Limosilactobacillus reuteri; Mice; Mice, Knockout; Multiple Sclerosis; Myxovirus Resistance Proteins; Nitric Oxide Synthase Type II; Optical Imaging; Polymerase Chain Reaction; Receptor, Interferon alpha-beta; Receptors, Aryl Hydrocarbon; Serotonin; STAT1 Transcription Factor; Suppressor of Cytokine Signaling Proteins; T-Lymphocytes; Tryptophan; Tryptophanase

2016
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study.
    BMC nephrology, 2016, 11-10, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Anxiety; Biomarkers; Cognition; Cross-Sectional Studies; Depression; Female; Glomerular Filtration Rate; Humans; Hydrocortisone; Indican; Indoleacetic Acids; Inflammation; Kynurenic Acid; Male; Middle Aged; Neopterin; Oxidative Stress; Pilot Projects; Prospective Studies; Renal Insufficiency, Chronic; Surveys and Questionnaires; Tasmania; Tryptophan

2016
Indoxyl sulfate - the uremic toxin linking hemostatic system disturbances with the prevalence of cardiovascular disease in patients with chronic kidney disease.
    BMC nephrology, 2017, 01-25, Volume: 18, Issue:1

    Topics: Adult; Aged; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Female; Hemostasis; Humans; Hydrogen Peroxide; Indican; Inflammation; Intercellular Adhesion Molecule-1; Lipoproteins; Male; Middle Aged; Neopterin; Oxidative Stress; Peptide Fragments; Plasminogen Activator Inhibitor 1; Prevalence; Prothrombin; Renal Insufficiency, Chronic; Thrombin; Thromboplastin; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator; Vascular Cell Adhesion Molecule-1; von Willebrand Factor

2017
p-Cresol sulfate and indoxyl sulfate induce similar cellular inflammatory gene expressions in cultured proximal renal tubular cells.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2013, Volume: 28, Issue:1

    Topics: Animals; Cells, Cultured; Cresols; Gene Expression; Indican; Inflammation; Kidney; Kidney Tubules, Proximal; Mice; Real-Time Polymerase Chain Reaction; Sulfuric Acid Esters

2013
Activation of aryl hydrocarbon receptor mediates indoxyl sulfate-induced monocyte chemoattractant protein-1 expression in human umbilical vein endothelial cells.
    Circulation journal : official journal of the Japanese Circulation Society, 2013, Volume: 77, Issue:1

    Topics: Chemokine CCL2; Dose-Response Relationship, Drug; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Indican; Inflammation; Oxidative Stress; Receptors, Aryl Hydrocarbon; Time Factors

2013
Reduction of indoxyl sulfate by AST-120 attenuates monocyte inflammation related to chronic kidney disease.
    Journal of leukocyte biology, 2013, Volume: 93, Issue:6

    Topics: Animals; Carbon; Cardiovascular Diseases; Cell Line; Disease Models, Animal; Flow Cytometry; Gastrointestinal Agents; Humans; Immunoblotting; Indican; Inflammation; Male; Mice; Mice, Inbred C57BL; Monocytes; Oxides; Reactive Oxygen Species; Renal Insufficiency, Chronic

2013