indican has been researched along with Disease Exacerbation in 42 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (4.76) | 18.2507 |
2000's | 7 (16.67) | 29.6817 |
2010's | 25 (59.52) | 24.3611 |
2020's | 8 (19.05) | 2.80 |
Authors | Studies |
---|---|
Donouchi, M; Kamada, S; Kanda, M; Kobuchi, S; Matsumura, Y; Nakagawa, K; Ohkita, M; Tanaka, R; Tawa, M | 1 |
Anarat, A; Anninos, A; Azukaitis, K; Balat, A; Bayazit, A; Bilginer, Y; Bulut, IK; Cakar, N; Caliskan, S; Candan, C; Canpolat, N; Duzova, A; Ertan, P; Habbig, S; Harambat, J; Holle, J; Kirchner, M; Kranz, B; Melk, A; Niemirska, A; Okun, J; Özcakar, ZB; Querfeld, U; Schaefer, F; Shroff, R; Soylemezoglu, O; Thurn-Valsassina, D; Tschumi, S; Yilmaz, E; Zurowska, A | 1 |
Abe, T; Kato, T; Maruyama, T; Matsuura, T; Obara, W; Onoda, M; Sasaki, N; Sugimura, J; Tatsumi, K | 1 |
Benkowitz, P; Cheng, Y; Köttgen, A; Lamina, C; Li, Y; Sekula, P | 1 |
Cao, YG; Fenn, K; Garrett, WS; Glickman, JN; Lobel, L | 1 |
Azukaitis, K; Baskin, E; Bayazit, AK; Bulut, IK; Büscher, R; Candan, C; Canpolat, N; Drozdz, D; Duzova, A; Erdogan, H; Gimpel, C; Holle, J; Jankauskiene, A; Kirchner, M; Klaus, G; Lugani, F; Melk, A; Nobili, F; Obrycki, L; Oh, J; Okun, J; Özcelik, G; Querfeld, U; Ranchin, B; Schaefer, F; Shroff, R; Yilmaz, A; Zaloszyc, A | 1 |
Drueke, TB; Massy, ZA | 1 |
Han, SY; Jeong, KH; Kang, DH; Kee, YK; Kim, BS; Kim, GH; Kim, YW; Noh, JW | 1 |
Bernasconi, H; Díaz-Castillo, ST; Echeverría, G; Fuentealba, J; García-Cancino, A; Jerez-Morales, A; Merino, JS; Smith, CT | 1 |
Gao, H; Liu, S | 1 |
Chen, CN; Chou, CC; Lee, YJ; Tsai, PSJ | 1 |
Fujimori, S; Higashino, T; Ichida, K; Matsuo, H; Miyata, H; Nakashima, A; Nakayama, A; Ooyama, H; Ooyama, K; Sakiyama, M; Shinomiya, N; Suzuki, H; Takada, T; Tan, JK; Toyoda, Y; Yamamoto, T; Yamanashi, Y | 1 |
Chou, CC; Lee, YJ; Liao, YL | 1 |
Chang, JC; Chen, YC; Chen, YT; Chu, PH; Fan, PC; Kou, G; Lee, CC; Lin, CN; Lu, YA; Yang, CW | 1 |
Autore, G; Dal Piaz, F; Di Iorio, B; Di Micco, L; Marzocco, S; Sirico, ML; Tartaglia, D; Torraca, S | 1 |
Niwa, T | 4 |
Al Khodor, S; Shatat, IF | 1 |
Chen, SC; Chung, FM; Houng, JY; Hsu, CC; Hung, WC; Lee, YJ; Lu, YC; Tang, WH; Tsai, IT; Wang, CP; Yu, TH | 1 |
Devlin, AS; Dodd, D; Fischbach, MA; Marcobal, A; Meyer, T; Nayfach, S; Plummer, N; Pollard, KS; Sonnenburg, JL | 1 |
Atoh, K; Haneda, M; Itoh, H | 1 |
Fasching, A; Fujita, T; Hansell, P; Kawakami, T; Nangaku, M; Nishijima, F; Nordquist, L; Palm, F; Tanaka, T | 1 |
Kojima, T; Morimoto, A; Morita, T; Namba, S; Okuda, Y | 1 |
Hsu, HJ; Hsu, KH; Lee, CC; Lin, CY; Sun, CY; Tsai, CJ; Tzen, CY; Wang, YC; Wu, IW; Wu, MS | 1 |
Evenepoel, P; Meijers, BK | 1 |
Fujii, H; Fukagawa, M; Nakai, K | 1 |
Kiss, I | 1 |
Drüeke, TB; Liabeuf, S; Massy, ZA | 1 |
Schulman, G | 1 |
Jang, YH; Kang, DH; Kim, SH; Ryu, ES; Yu, MA | 1 |
Chen, CH; Cheng, CH; Chuang, YW; Huang, ST; Shu, KH; Wu, MJ; Yu, TM | 1 |
Hirashiki, A; Kondo, T; Murohara, T; Niwa, T; Okamoto, R; Okumura, T; Shimazu, S; Shinoda, N; Takeshita, K; Yamada, T | 1 |
Hayashi, M; Inoue, Y; Ishii, H; Kumagai, S; Matsubara, T; Matsumoto, M; Murohara, T; Niwa, T; Okumura, S; Sato, B; Suzuki, S; Takeshita, K; Tanaka, M; Yoshikawa, D | 1 |
Niwa, T; Taki, K | 1 |
Niwa, T; Taki, K; Tsuruta, Y | 1 |
Adijiang, A; Goto, S; Nishijima, F; Niwa, T; Uramoto, S | 1 |
Ise, M; Miyazaki, T; Niwa, T; Owada, A; Shiigai, T; Tsubakihara, Y; Tsukushi, S | 1 |
Endo, K; Hirata, M; Ise, M; Ito, Y; Miyazaki, T; Niwa, T; Seo, H | 1 |
Aoyama, I; Niwa, T | 1 |
Aoyama, I; Niwa, T; Shimokata, K | 1 |
7 review(s) available for indican and Disease Exacerbation
Article | Year |
---|---|
Role of uremic toxin indoxyl sulfate in the progression of cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Coronary Artery Disease; Disease Progression; Humans; Indican; NADPH Oxidases; Oxidation-Reduction; Oxidative Stress; Renal Insufficiency, Chronic | 2017 |
Targeting protein-bound uremic toxins in chronic kidney disease.
Topics: Bone and Bones; Carbon; Cardiovascular System; Disease Progression; Erythropoietin; Humans; Indican; Kidney; Kidney Failure, Chronic; Oxides; Protein Binding; Reactive Oxygen Species | 2013 |
Gut microbiome and kidney disease: a bidirectional relationship.
Topics: Carbon; Child; Dietary Supplements; Disease Progression; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Humans; Hypertension; Indican; Indoles; Oxides; Renal Dialysis; Renal Insufficiency, Chronic | 2017 |
The role of carbon adsorbent in the conservative management of chronic kidney disease.
Topics: Adsorption; Animals; Carbon; Conservative Treatment; Disease Progression; Humans; Indican; Kidney Failure, Chronic; Mice; Oxidative Stress; Oxides; Patient Safety; Rats; Reactive Oxygen Species | 2017 |
[The uremic toxin, indoxyl sulfate, signifies cardio-renal risk and intestinal-renal relationship].
Topics: Biomarkers; Cardiovascular Diseases; Disease Progression; Humans; Indican; Intestinal Mucosa; Intestines; Kidney; Kidney Failure, Chronic; Risk Factors; Uremia | 2011 |
Protein-bound uremic toxins: new insight from clinical studies.
Topics: Cardiovascular Diseases; Cresols; Disease Progression; Heart; Humans; Indican; Kidney; Protein Binding; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Toxins, Biological; Uremia | 2011 |
A nexus of progression of chronic kidney disease: tryptophan, profibrotic cytokines, and charcoal.
Topics: Adsorption; Carbon; Disease Progression; Fibrosis; Humans; Indican; Intestinal Absorption; Kidney Failure, Chronic; Microspheres; Oxides; Renin-Angiotensin System; Transforming Growth Factor beta; Tryptophan | 2012 |
3 trial(s) available for indican and Disease Exacerbation
Article | Year |
---|---|
Comparison of Different Types of Oral Adsorbent Therapy in Patients with Chronic Kidney Disease: A Multicenter, Randomized, Phase IV Clinical Trial.
Topics: Adsorption; Carbon; Creatinine; Cross-Over Studies; Cystatin C; Disease Progression; Female; Glomerular Filtration Rate; Humans; Indican; Male; Middle Aged; Oxides; Renal Insufficiency, Chronic; Treatment Outcome | 2021 |
Very low protein diet reduces indoxyl sulfate levels in chronic kidney disease.
Topics: Aged; Amino Acids; Case-Control Studies; Creatinine; Cross-Over Studies; Diet, Protein-Restricted; Disease Progression; Female; Fibroblast Growth Factor-23; Humans; Indican; Keto Acids; Male; Middle Aged; Pilot Projects; Prospective Studies; Renal Dialysis; Renal Insufficiency, Chronic; Treatment Outcome | 2013 |
Indoxyl sulfate and progression of renal failure: effects of a low-protein diet and oral sorbent on indoxyl sulfate production in uremic rats and undialyzed uremic patients.
Topics: Administration, Oral; Adsorption; Adult; Aged; Animals; Carbon; Dietary Proteins; Disease Progression; Fasting; Female; Humans; Indican; Male; Microspheres; Middle Aged; Oxides; Rats; Rats, Sprague-Dawley; Renal Dialysis; Renal Insufficiency; Uremia | 1997 |
32 other study(ies) available for indican and Disease Exacerbation
Article | Year |
---|---|
Vascular Endothelial Dysfunction in the Thoracic Aorta of Rats with Ischemic Acute Kidney Injury: Contribution of Indoxyl Sulfate.
Topics: Acute Kidney Injury; Animals; Aorta, Thoracic; Carbon; Disease Models, Animal; Disease Progression; Endothelial Cells; Endothelium, Vascular; Indican; Ischemia; Male; Nitric Oxide; Oxides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recovery of Function; Renal Insufficiency, Chronic; Reperfusion Injury; Signal Transduction | 2022 |
Indoxyl sulfate associates with cardiovascular phenotype in children with chronic kidney disease.
Topics: Adolescent; Biomarkers; Cardiovascular Diseases; Child; Cresols; Disease Progression; Female; Glomerular Filtration Rate; Humans; Indican; Male; Phenotype; Renal Insufficiency, Chronic; Sulfuric Acid Esters | 2019 |
Evaluation of a new measurement method of indoxyl sulfate in hemodialysis patients.
Topics: Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Clinical Enzyme Tests; Disease Progression; Humans; Indican; Limit of Detection; Renal Dialysis; Reproducibility of Results | 2021 |
The relationship between blood metabolites of the tryptophan pathway and kidney function: a bidirectional Mendelian randomization analysis.
Topics: Biomarkers; Disease Progression; Glomerular Filtration Rate; Humans; Indican; Indoles; Kynurenine; Mendelian Randomization Analysis; Renal Insufficiency, Chronic; Tryptophan | 2020 |
Diet posttranslationally modifies the mouse gut microbial proteome to modulate renal function.
Topics: Animals; Diet; Dietary Proteins; Disease Models, Animal; Disease Progression; Escherichia coli; Gastrointestinal Microbiome; Hydrogen Sulfide; Indican; Kidney; Mice; Protein Processing, Post-Translational; Proteome; Renal Insufficiency, Chronic; Toxins, Biological; Tryptophanase | 2020 |
Serum indoxyl sulfate concentrations associate with progression of chronic kidney disease in children.
Topics: Adolescent; Biomarkers; Child; Cresols; Disease Progression; Female; Humans; Indican; Kaplan-Meier Estimate; Male; Proportional Hazards Models; Prospective Studies; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Survival Analysis | 2020 |
Diet-microbiota interaction and kidney disease progression.
Topics: Animals; Diet; Disease Progression; Gastrointestinal Microbiome; Indican; Kidney; Mice; Proteome | 2021 |
The Administration of the Synbiotic
Topics: Animals; Creatinine; Disease Models, Animal; Disease Progression; Female; Fibrosis; Heart Diseases; Indican; Inulin; Kidney; Lactobacillus delbrueckii; Myocardium; Oligosaccharides; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Synbiotics; Toxins, Biological | 2021 |
Plasma indoxyl sulfate concentration predicts progression of chronic kidney disease in dogs and cats.
Topics: Animals; Biomarkers; Blood Urea Nitrogen; Cat Diseases; Cats; Creatinine; Disease Progression; Dog Diseases; Dogs; Indican; Phosphates; Renal Insufficiency, Chronic; Species Specificity | 2018 |
Identification of ABCG2 as an Exporter of Uremic Toxin Indoxyl Sulfate in Mice and as a Crucial Factor Influencing CKD Progression.
Topics: Adenine; Adenosine Triphosphate; Analysis of Variance; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Chromatography, Liquid; Disease Models, Animal; Disease Progression; Gene Knockout Techniques; Half-Life; HEK293 Cells; Humans; Indican; Mice; Mice, Knockout; Neoplasm Proteins; Renal Elimination; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Toxins, Biological; Transport Vesicles | 2018 |
The association of indoxyl sulfate with fibroblast growth factor-23 in cats with chronic kidney disease.
Topics: Animals; Case-Control Studies; Cat Diseases; Cats; Chromatography, High Pressure Liquid; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Indican; Male; Renal Insufficiency, Chronic; Retrospective Studies; Severity of Illness Index | 2019 |
Serum indoxyl sulfate predicts adverse cardiovascular events in patients with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Disease Progression; Female; Humans; Indican; Male; Mass Spectrometry; Middle Aged; Multivariate Analysis; Renal Insufficiency, Chronic; ROC Curve; Taiwan; Tertiary Care Centers | 2019 |
Increased Levels of Total p-Cresylsulfate Are Associated with Pruritus in Patients with Chronic Kidney Disease.
Topics: Aged; Biomarkers; Cresols; Cross-Sectional Studies; Disease Progression; Female; Glomerular Filtration Rate; Humans; Indican; Male; Middle Aged; Pruritus; Renal Insufficiency, Chronic; Sulfuric Acid Esters | 2016 |
Modulation of a Circulating Uremic Solute via Rational Genetic Manipulation of the Gut Microbiota.
Topics: Animal Feed; Animals; Bacteria; Bacteroides; Diet; Disease Models, Animal; Disease Progression; Gastrointestinal Microbiome; Gastrointestinal Tract; Genetic Engineering; Germ-Free Life; Humans; Indican; Indoles; Metagenome; Mice; Microbiota; Renal Insufficiency, Chronic; Toxins, Biological; Tryptophan; Tryptophanase | 2016 |
Serum indoxyl sulfate levels in patients with diabetic nephropathy: relation to renal function.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diagnostic Techniques, Endocrine; Disease Progression; Female; Glomerular Filtration Rate; Humans; Indican; Kidney; Kidney Failure, Chronic; Male; Middle Aged | 2009 |
Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress.
Topics: Acetophenones; Animals; Carbon; Cell Hypoxia; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Humans; Indican; Indoles; Kidney Failure, Chronic; Kidney Tubules, Proximal; Male; NADPH Oxidases; Nephrectomy; Ouabain; Oxidative Stress; Oxides; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Time Factors; Uremia | 2010 |
[Serum indoxyl sulfate is a useful predictor for progression of chronic kidney disease].
Topics: Aged; Biomarkers; Chronic Disease; Disease Progression; Female; Humans; Indican; Kidney Diseases; Male; Middle Aged; Predictive Value of Tests | 2010 |
p-Cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease.
Topics: Aged; Biomarkers; Cohort Studies; Creatinine; Cresols; Disease Progression; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Indican; Kidney Failure, Chronic; Kidney Function Tests; Male; Prognosis; Prospective Studies; Risk Factors; Sulfuric Acid Esters; Survival Rate; Uremia | 2011 |
The gut-kidney axis: indoxyl sulfate, p-cresyl sulfate and CKD progression.
Topics: Chronic Disease; Cresols; Disease Progression; Humans; Indican; Kidney Diseases; Sulfuric Acid Esters | 2011 |
Role of oxidative stress and indoxyl sulfate in progression of cardiovascular disease in chronic kidney disease.
Topics: Animals; Carbon; Cardiovascular Diseases; Chronic Disease; Disease Progression; Drug Delivery Systems; Humans; Indican; Kidney Diseases; Oxidative Stress; Oxides; Uremia | 2011 |
Role of indoxyl sulfate in the progression of chronic kidney disease and cardiovascular disease: experimental and clinical effects of oral sorbent AST-120.
Topics: Animals; Carbon; Cardiovascular Diseases; Chronic Disease; Disease Progression; Humans; Indican; Kidney Diseases; Oxidative Stress; Oxides; Protein Binding; Rats; Uremia | 2011 |
Indoxyl sulfate-induced epithelial-to-mesenchymal transition and apoptosis of renal tubular cells as novel mechanisms of progression of renal disease.
Topics: Actins; Animals; Apoptosis; Cadherins; Cell Line; Cell Movement; Cell Proliferation; Disease Progression; Enzyme Activation; Epithelial-Mesenchymal Transition; Indican; Membrane Proteins; Mitogen-Activated Protein Kinase 1; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Rats; Renal Insufficiency, Chronic; Signal Transduction; Zonula Occludens-1 Protein | 2012 |
Serum total p-cresol and indoxyl sulfate correlated with stage of chronic kidney disease in renal transplant recipients.
Topics: Adult; Cresols; Disease Progression; Female; Humans; Indican; Kidney Failure, Chronic; Kidney Transplantation; Male | 2012 |
Association between indoxyl sulfate and cardiac dysfunction and prognosis in patients with dilated cardiomyopathy.
Topics: Adult; Aged; Biomarkers; Cardiomyopathy, Dilated; Disease Progression; Female; Heart Failure; Humans; Indican; Kaplan-Meier Estimate; Male; Middle Aged; Natriuretic Peptide, Brain; Predictive Value of Tests; Prognosis; Renal Insufficiency, Chronic; Risk Factors; Stroke Volume; Ultrasonography; Uremia | 2013 |
Relation of plasma indoxyl sulfate levels and estimated glomerular filtration rate to left ventricular diastolic dysfunction.
Topics: Aged; Biomarkers; Chromatography, High Pressure Liquid; Diastole; Disease Progression; Echocardiography; Female; Follow-Up Studies; Glomerular Filtration Rate; Heart Ventricles; Humans; Indican; Male; Prognosis; Prospective Studies; Renal Insufficiency, Chronic; Ventricular Dysfunction, Left; Ventricular Function, Left | 2013 |
Indoxyl sulfate-lowering capacity of oral sorbents affects the prognosis of kidney function and oxidative stress in chronic kidney disease.
Topics: Acrolein; Administration, Oral; Adsorption; Animals; Biomarkers; Carbon; Chronic Disease; Creatinine; Disease Progression; Gastrointestinal Agents; Indican; Kidney Diseases; Male; Oxidative Stress; Oxides; Prognosis; Rats; Rats, Sprague-Dawley | 2007 |
Indoxyl sulfate and atherosclerotic risk factors in hemodialysis patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Atherosclerosis; Biomarkers; C-Reactive Protein; Cholesterol, HDL; Chromatography, High Pressure Liquid; Creatinine; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Incidence; Indican; Lysine; Male; Middle Aged; Nephelometry and Turbidimetry; Renal Dialysis; Uremia | 2007 |
Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats.
Topics: Analysis of Variance; Animals; Aortic Diseases; Blood Pressure; Calcinosis; Core Binding Factors; Disease Models, Animal; Disease Progression; Immunohistochemistry; Indican; Kidney Glomerulus; Organic Anion Transporters, Sodium-Independent; Osteoblasts; Osteopontin; Random Allocation; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary | 2008 |
Indoxyl sulfate stimulates renal synthesis of transforming growth factor-beta 1 and progression of renal failure.
Topics: Animals; Cells, Cultured; Disease Progression; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Indican; Intercellular Adhesion Molecule-1; Kidney; Kidney Failure, Chronic; Rats; RNA, Messenger; Swine; Transforming Growth Factor beta | 1997 |
An oral adsorbent ameliorates renal overload of indoxyl sulfate and progression of renal failure in diabetic rats.
Topics: Administration, Oral; Animals; Blood Urea Nitrogen; Carbon; Cholesterol; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Immunohistochemistry; Indican; Kidney; Kidney Failure, Chronic; Kidney Glomerulus; Male; Oxides; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Treatment Outcome; Triglycerides | 2001 |
The protein metabolite theory as a mechanism for the progression of renal failure.
Topics: Carbon; Dietary Proteins; Disease Progression; Humans; Indican; Kidney Failure, Chronic; Oxides; Uremia | 2001 |
Combination therapy with benazepril and oral adsorbent ameliorates progressive renal fibrosis in uremic rats.
Topics: Adsorption; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Blood Pressure; Carbon; Cells, Cultured; Disease Progression; Drug Therapy, Combination; Fibroblasts; Fibrosis; Humans; In Situ Hybridization; Indican; Kidney; Kidney Diseases; Male; Nephrectomy; Nephrosclerosis; Osteopontin; Oxides; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Transforming Growth Factor beta1; Uremia | 2002 |