indican has been researched along with Cardiovascular Diseases in 57 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.75) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (1.75) | 29.6817 |
| 2010's | 42 (73.68) | 24.3611 |
| 2020's | 13 (22.81) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, CH; Chang, KT; Huang, YC; Ko, PH; Lai, LC; Tsai, TC | 1 |
| Bataille, S; Brunet, P; Burtey, S; Dou, L; Fraisse, M; Lano, G; McKay, N; Pelletier, M; Sallée, M | 1 |
| Arcidiacono, T; Avino, M; Belloni, C; Bisegna, S; Bologna, A; Conte, F; Foligno, N; Locatelli, M; Macrina, L; Magni, G; Palmieri, N; Premaschi, S; Simonini, M; Slaviero, G; Vezzoli, G | 1 |
| Hu, D; Li, C; Peng, A; Wang, Q; Xue, W; Yu, H; Zhou, C | 1 |
| Bagnati, M; Carrera, D; Chiarinotti, D; De Mauri, A; Riso, S; Rolla, R; Torreggiani, M; Vidali, M | 1 |
| Jiang, BW; Jin, YX; Li, Q; Liu, SX; Mu, XW; Song, JN; Wang, SN; Wang, XN; Wang, ZH; Wang, ZZ; Wu, QJ; Xiao, J; Yan, XY; You, LL; Zhang, S; Zhang, Y; Zhao, XN | 1 |
| Altomare, A; Astori, E; Colombo, G; Dalle-Donne, I; Gagliano, N; Garavaglia, ML; Giustarini, D; Landoni, L; Lionetti, MC; Milzani, A; Rossi, R | 1 |
| Chen, Z; Gao, S; Luo, X; Mao, Z; Xing, X; Xu, J; Xue, C | 1 |
| Arefin, S; de Loor, H; Ebert, T; Evenepoel, P; Hernandez, L; Hobson, S; Kublickiene, K; Rahman, A; Stenvinkel, P | 1 |
| Huang, L; Liu, L; Liu, XY; Liu, YF; Lu, C; Tang, MY; Wu, L; Zhang, C | 1 |
| Anarat, A; Anninos, A; Azukaitis, K; Balat, A; Bayazit, A; Bilginer, Y; Bulut, IK; Cakar, N; Caliskan, S; Candan, C; Canpolat, N; Duzova, A; Ertan, P; Habbig, S; Harambat, J; Holle, J; Kirchner, M; Kranz, B; Melk, A; Niemirska, A; Okun, J; Özcakar, ZB; Querfeld, U; Schaefer, F; Shroff, R; Soylemezoglu, O; Thurn-Valsassina, D; Tschumi, S; Yilmaz, E; Zurowska, A | 1 |
| Burtey, S; Lano, G; Sallée, M | 1 |
| Abe, T; Kato, T; Maruyama, T; Matsuura, T; Obara, W; Onoda, M; Sasaki, N; Sugimura, J; Tatsumi, K | 1 |
| Cosola, C; Gesualdo, L; Ranieri, E; Rocchetti, MT | 1 |
| Borges, NA; Brito, JS; Esgalhado, M; Mafra, D; Magliano, DC; Soulage, CO | 1 |
| Banerjee, T; Coresh, J; Hostetter, TH; Hwang, S; Melamed, ML; Meyer, TW; Plummer, NS; Powe, NR; Shafi, T; Sirich, TL | 1 |
| Gao, H; Liu, S | 1 |
| Addi, T; Brunet, P; Burtey, S; Cerini, C; Denison, MS; Dignat-George, F; Dou, L; Duval-Sabatier, A; Gondouin, B; Jourde-Chiche, N; McKay, N; Poitevin, S; Sallée, M | 1 |
| Li, DY; Tang, WHW | 1 |
| Chillon, JM; Hénaut, L; Kamel, S; Massy, ZA | 1 |
| Amano, H; Fujii, T; Ikeda, T; Koike, H; Morita, T; Nakanishi, R; Noike, R; Okubo, R; Saito, D; Tatebe, J; Toda, M; Watanabe, I; Yabe, T | 1 |
| Guo, CC; Xia, WW; Zhang, AH | 1 |
| Jin, M; Qian, Z; Xu, W; Yin, J; Zhou, X | 1 |
| Chang, JC; Chen, YC; Chen, YT; Chu, PH; Fan, PC; Kou, G; Lee, CC; Lin, CN; Lu, YA; Yang, CW | 1 |
| Ayajiki, K; Ito, S; Jun-Ichi, S; Kobuchi, S; Manabe, E; Masuyama, T; Ohno, Y; Tanaka, T; Tsujino, T | 1 |
| Coresh, J; Hostetter, TH; Melamed, ML; Meyer, TW; Parekh, R; Plantinga, L; Powe, NR; Shafi, T | 1 |
| Watanabe, H | 1 |
| Chen, HH; Chuang, CK; Lin, CJ; Liu, HL; Pan, CF; Sun, FJ; Wang, TJ; Wu, CJ | 1 |
| Cheng, BC; Chiou, TT; Hsu, CY; Lee, CT; Lee, YT; Liao, SC; Ng, HY; Tain, YL; Wu, CH; Yang, CC | 1 |
| Campbell, KL; Coombes, JS; Hawley, CM; Isbel, N; Johnson, DW; McWhinney, BC; Rossi, M; Stanton, T; Ungerer, JP; Vesey, DA; Weston, KS | 1 |
| Brunet, P; Gondouin, B; Meyer, TW; Niwa, T; Sirich, TL | 1 |
| Claes, K; Evenepoel, P; Gu, Y; Jin, Y; Liu, Y; Meijers, B; Staessen, J; Thijs, L; Viaene, L | 1 |
| Campbell, K; Dimeski, G; Hawley, C; Isbel, N; Johnson, D; McWhinney, B; Pascoe, E; Rossi, M; Stanton, T; Ungerer, J | 1 |
| Ameri, P; Balbi, M; Barisione, C; Brunelli, C; Canepa, M; Ghigliotti, G | 1 |
| Banerjee, T; Coresh, J; Hostetter, TH; Hwang, S; Melamed, ML; Meyer, TW; Parekh, RS; Powe, NR; Shafi, T | 1 |
| Lin, CJ; Wu, CJ; Wu, PC; Wu, V | 1 |
| Chillon, JM; Drueke, TB; Gross, P; Massy, ZA; Poirot, S; Rémond, MC; Six, I | 1 |
| Liu, X; Lu, F; Lu, Z; Zeng, Y; Zheng, Y; Zou, C | 1 |
| Cha, MU; Han, SH; Jhee, JH; Jung, SY; Kang, HY; Kang, SW; Kee, YK; Kim, H; Kim, HC; Kim, S; Kwon, YE; Lee, M; Lim, SK; Nam, BY; Park, J; Park, JT; Park, S; Seo, C; Um, JE; Wu, M; Yoo, TH; Yoon, CY; Yun, HR | 1 |
| Ando, Y; Ishida, H; Ito, K; Kurabayashi, M; Negishi, K; Obokata, M; Ogawa, T; Sunaga, H | 1 |
| Liabeuf, S; Massy, ZA; Villain, C | 1 |
| Hazen, SL; Skye, SM | 1 |
| Kamiński, TW; Karbowska, M; Myśliwiec, M; Pawlak, D; Pawlak, K | 1 |
| Hung, SC; Kuo, KL; Tarng, DC; Wu, CC | 1 |
| Enomoto, A; Muteliefu, G; Niwa, T | 1 |
| Niwa, T | 2 |
| Fujii, H; Fukagawa, M; Nakai, K | 1 |
| Maruyama, T; Miyamoto, Y; Otagiri, M; Watanabe, H | 1 |
| Kiss, I | 1 |
| Drüeke, TB; Liabeuf, S; Massy, ZA | 1 |
| Niwa, T; Shimizu, H | 1 |
| Chen, HH; Chuang, CK; Jayakumar, T; Lin, CJ; Liu, HL; Pan, CF; Wang, TJ; Wu, CJ | 1 |
| Eloot, S; Glorieux, G; Neirynck, N; Pletinck, A; Schepers, E; Vanholder, R | 1 |
| Boelaert, J; Eloot, S; Glorieux, G; Lynen, F; Sandra, P; Van Landschoot, M; Vanholder, R; Waterloos, MA | 1 |
| Higuchi, Y; Ishii, H; Ito, S; Nishijima, F; Osaka, M; Yagi, Y; Yamato, H; Yoshida, M | 1 |
| Dobbelstein, H | 1 |
21 review(s) available for indican and Cardiovascular Diseases
| Article | Year |
|---|---|
Topics: Cardiovascular Diseases; Cohort Studies; Cresols; Follow-Up Studies; Humans; Indican; Kidney Failure, Chronic; Peritoneal Dialysis; Peritonitis; Prospective Studies; Sulfates; Sulfuric Acid Esters | 2022 |
Indoxyl sulfate in atherosclerosis.
Topics: Albumins; Atherosclerosis; Cardiovascular Diseases; Chronic Disease; Humans; Indican; Renal Insufficiency, Chronic; Uremia | 2023 |
Indoxyl Sulfate, a Uremic Endotheliotoxin.
Topics: Animals; Cardiovascular Diseases; Endothelium, Vascular; Humans; Indican; Prognosis; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors; Signal Transduction; Toxins, Biological; Uremia | 2020 |
Protein-Bound Uremic Toxins and Immunity.
Topics: Adaptive Immunity; Cardiovascular Diseases; Cresols; Gastrointestinal Microbiome; Humans; Immunity, Innate; Indican; Inflammation; Renal Insufficiency, Chronic; Sulfuric Acid Esters; T-Lymphocytes; Toxins, Biological; Uremia | 2021 |
Aryl Hydrocarbon Receptor Activation in Chronic Kidney Disease: Role of Uremic Toxins.
Topics: Animals; Cardiovascular Diseases; Glucuronates; Humans; Indican; Indoleacetic Acids; Indoles; Models, Biological; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Toxins, Biological; Tryptophan; Uremia | 2017 |
Role of uremic toxin indoxyl sulfate in the progression of cardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Coronary Artery Disease; Disease Progression; Humans; Indican; NADPH Oxidases; Oxidation-Reduction; Oxidative Stress; Renal Insufficiency, Chronic | 2017 |
Contributory Role of Gut Microbiota and Their Metabolites Toward Cardiovascular Complications in Chronic Kidney Disease.
Topics: Animals; Cardiovascular Diseases; Cresols; Diet Therapy; Dietary Supplements; Dysbiosis; Enzyme Inhibitors; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Indican; Inflammation; Methylamines; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Toxins, Biological | 2018 |
Updates on the Mechanisms and the Care of Cardiovascular Calcification in Chronic Kidney Disease.
Topics: Animals; Anti-Inflammatory Agents; Calcimimetic Agents; Calcium; Cardiovascular Diseases; Chelating Agents; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Glucuronidase; Glycation End Products, Advanced; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indican; Inflammation; Klotho Proteins; Magnesium; Mesenchymal Stem Cells; Phosphates; Renal Insufficiency, Chronic; Tunica Intima; Tunica Media; Vascular Calcification; Vitamin K 2; Zinc Finger Protein GLI1 | 2018 |
[Research progress of the uremic toxin indoxyl sulfate in cardiovascular complication of end-stage renal diseases].
Topics: Cardiovascular Diseases; Humans; Indican; Kidney Failure, Chronic; Oxidative Stress; Toxins, Biological | 2018 |
The role of intestinal microbiota in cardiovascular disease.
Topics: Bile Acids and Salts; Cardiovascular Diseases; Dysbiosis; Fatty Acids; Gastrointestinal Microbiome; Heart Failure; Humans; Hypertension; Indican; Methylamines; Probiotics; Signal Transduction | 2019 |
Molecular mechanisms for uremic toxin-induced oxidative tissue damage via a cardiovascular-renal connection.
Topics: Cardiovascular Diseases; Cresols; Humans; Indican; Kidney Failure, Chronic; Oxidation-Reduction; Oxidative Stress; Sulfuric Acid Esters | 2013 |
Indoxyl sulfate: a candidate target for the prevention and treatment of cardiovascular disease in chronic kidney disease.
Topics: Animals; Anti-Inflammatory Agents; Basic Helix-Loop-Helix Transcription Factors; Cardiovascular Diseases; Drug Design; Humans; Indican; Inflammation Mediators; Molecular Targeted Therapy; Receptors, Aryl Hydrocarbon; Renal Dialysis; Renal Insufficiency, Chronic; Risk Factors; Signal Transduction | 2015 |
Meta-Analysis of the Associations of p-Cresyl Sulfate (PCS) and Indoxyl Sulfate (IS) with Cardiovascular Events and All-Cause Mortality in Patients with Chronic Renal Failure.
Topics: Biomarkers; Cardiovascular Diseases; Cresols; Humans; Indican; Kidney Failure, Chronic; Risk Factors; Sulfuric Acid Esters; Toxins, Biological; Uremia | 2015 |
Protein-bound toxins: has the Cinderella of uraemic toxins turned into a princess?
Topics: Animals; Cardiovascular Diseases; Cresols; Humans; Indican; Indoleacetic Acids; Proteins; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Uremia | 2016 |
Indoxyl Sulfate: A Novel Cardiovascular Risk Factor in Chronic Kidney Disease.
Topics: Biomarkers; Cardiovascular Diseases; Humans; Indican; Renal Insufficiency, Chronic; Risk Factors | 2017 |
Indoxyl sulfate is a nephro-vascular toxin.
Topics: Adsorption; Animals; Carbon; Cardiovascular Diseases; Free Radicals; Glomerular Mesangium; Humans; Indican; Kidney Diseases; Kidney Tubules; Models, Biological; Oxidative Stress; Oxides; Proteins; Uremia | 2010 |
[The uremic toxin, indoxyl sulfate, signifies cardio-renal risk and intestinal-renal relationship].
Topics: Biomarkers; Cardiovascular Diseases; Disease Progression; Humans; Indican; Intestinal Mucosa; Intestines; Kidney; Kidney Failure, Chronic; Risk Factors; Uremia | 2011 |
Protein-bound uremic toxins: new insight from clinical studies.
Topics: Cardiovascular Diseases; Cresols; Disease Progression; Heart; Humans; Indican; Kidney; Protein Binding; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Toxins, Biological; Uremia | 2011 |
Indoxyl sulfate induces nephrovascular senescence.
Topics: Animals; Aorta; Cardiovascular Diseases; Cellular Senescence; Endothelial Cells; Gene Expression; Glucuronidase; Humans; Hypertension; Indican; Kidney Failure, Chronic; Kidney Tubules, Proximal; Klotho Proteins; NF-kappa B; Nitric Oxide; Rats; Reactive Oxygen Species; Uremia | 2012 |
An update on uremic toxins.
Topics: beta 2-Microglobulin; Biomarkers; Cardiovascular Diseases; Cresols; Dialysis Solutions; Fibroblast Growth Factor-23; Glucuronides; Guanidines; Humans; Indican; Peptides; Protein Binding; Renal Dialysis; Sulfuric Acid Esters; Urea; Uremia | 2013 |
[Pathogenesis of uremia].
Topics: Acidosis; Aminobenzoates; Ammonia; Anemia; Animals; Butyrates; Cardiovascular Diseases; Central Nervous System Diseases; Cinnamates; Creatinine; Dogs; Endocrine System Diseases; Gastroenteritis; Glomerular Filtration Rate; Guanidines; Guanine; Guinea Pigs; Haplorhini; Hemorrhagic Disorders; Hominidae; Humans; In Vitro Techniques; Indican; Mice; Phenols; Phosphates; Pruritus; Pulmonary Edema; Pyruvates; Rabbits; Rats; Urea; Uremia | 1971 |
1 trial(s) available for indican and Cardiovascular Diseases
| Article | Year |
|---|---|
Results of the HEMO Study suggest that p-cresol sulfate and indoxyl sulfate are not associated with cardiovascular outcomes.
Topics: Adult; Aged; Cardiovascular Diseases; Cresols; Female; Glutamine; Hippurates; Humans; Indican; Kidney Failure, Chronic; Longitudinal Studies; Male; Middle Aged; Renal Dialysis; Risk Factors; Serum Albumin; Sulfuric Acid Esters; Uremia | 2017 |
35 other study(ies) available for indican and Cardiovascular Diseases
| Article | Year |
|---|---|
Indoxyl Sulfate Elevated Lnc-SLC15A1-1 Upregulating CXCL10/CXCL8 Expression in High-Glucose Endothelial Cells by Sponging MicroRNAs.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Chemokine CXCL10; Diabetes Mellitus, Type 2; Endothelial Cells; Female; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Indican; Male; MicroRNAs; Middle Aged; Peptide Transporter 1; Renal Insufficiency, Chronic; Toxins, Biological; Up-Regulation | 2021 |
Neutrophil:lymphocyte ratio correlates with the uremic toxin indoxyl sulfate and predicts the risk of death in patients on hemodialysis.
Topics: Biomarkers; Cardiovascular Diseases; Humans; Indican; Lymphocytes; Neutrophils; Prospective Studies; Renal Dialysis; Renal Insufficiency, Chronic; Toxins, Biological; Uremic Toxins | 2022 |
Serum concentrations of free indoxyl and p-cresyl sulfate are associated with mineral metabolism variables and cardiovascular risk in hemodialysis patients.
Topics: Biomarkers; Calcium; Cardiovascular Diseases; Cresols; Heart Disease Risk Factors; Humans; Indican; Indoles; Minerals; Phosphates; Renal Dialysis; Risk Factors; Sulfates; Sulfuric Acid Esters | 2022 |
Uremic toxin indoxyl sulfate induces dysfunction of vascular smooth muscle cells via integrin-β1/ERK signaling pathway.
Topics: Cardiovascular Diseases; Endothelial Cells; Humans; Indican; Integrin beta1; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Renal Insufficiency, Chronic; Signal Transduction; Uremic Toxins | 2022 |
Does Mediterranean Adequacy Index Correlate with Cardiovascular Events in Patients with Advanced Chronic Kidney Disease? An Exploratory Study.
Topics: Adult; Cardiovascular Diseases; Diet, Mediterranean; Female; Humans; Indican; Male; Quality of Life; Renal Insufficiency, Chronic; Sulfates; Toxins, Biological | 2022 |
Serum total indoxyl sulfate levels and all-cause and cardiovascular mortality in maintenance hemodialysis patients: a prospective cohort study.
Topics: Cardiovascular Diseases; Humans; Indican; Proportional Hazards Models; Prospective Studies; Renal Dialysis | 2022 |
Effects of the uremic toxin indoxyl sulphate on human microvascular endothelial cells.
Topics: Cardiovascular Diseases; Endothelial Cells; Humans; Indican; Proteomics; Renal Insufficiency, Chronic; Uremic Toxins | 2022 |
Indoxyl Sulphate Retention Is Associated with Microvascular Endothelial Dysfunction after Kidney Transplantation.
Topics: Cardiovascular Diseases; Endothelium, Vascular; Humans; Indican; Kidney Transplantation; Nitroprusside; Quality of Life; Renal Insufficiency, Chronic; Vascular Diseases | 2023 |
Indoxyl sulfate associates with cardiovascular phenotype in children with chronic kidney disease.
Topics: Adolescent; Biomarkers; Cardiovascular Diseases; Child; Cresols; Disease Progression; Female; Glomerular Filtration Rate; Humans; Indican; Male; Phenotype; Renal Insufficiency, Chronic; Sulfuric Acid Esters | 2019 |
Evaluation of a new measurement method of indoxyl sulfate in hemodialysis patients.
Topics: Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Clinical Enzyme Tests; Disease Progression; Humans; Indican; Limit of Detection; Renal Dialysis; Reproducibility of Results | 2021 |
Aryl hydrocarbon receptor is activated in patients and mice with chronic kidney disease.
Topics: Adult; Aged; Aged, 80 and over; Animals; Basic Helix-Loop-Helix Transcription Factors; Cardiovascular Diseases; Case-Control Studies; Cause of Death; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Disease Models, Animal; Female; Humans; Indican; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Prospective Studies; Receptors, Aryl Hydrocarbon; Renal Dialysis; Renal Insufficiency, Chronic; Repressor Proteins; Risk Factors; Treatment Outcome | 2018 |
Prognostic Significance of Serum Indoxyl Sulfate and Albumin for Patients with Cardiovascular Disease.
Topics: Aged; Cardio-Renal Syndrome; Cardiovascular Diseases; Coronary Artery Disease; Female; Humans; Indican; Male; Middle Aged; Mortality; Percutaneous Coronary Intervention; Peripheral Arterial Disease; Prognosis; Prospective Studies; Risk Factors; Serum Albumin; Stroke Volume; Toxins, Biological | 2019 |
Serum indoxyl sulfate predicts adverse cardiovascular events in patients with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Disease Progression; Female; Humans; Indican; Male; Mass Spectrometry; Middle Aged; Multivariate Analysis; Renal Insufficiency, Chronic; ROC Curve; Taiwan; Tertiary Care Centers | 2019 |
Neutrophil/lymphocyte ratio elevation in renal dysfunction is caused by distortion of leukocyte hematopoiesis in bone marrow.
Topics: Adenine; Aged; Aged, 80 and over; Animals; Biomarkers; Bone Marrow; Carbon; Cardiovascular Diseases; Disease Models, Animal; Female; Glomerular Filtration Rate; Hematopoiesis; Humans; Indican; Kidney Diseases; Lymphocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Middle Aged; Neutrophils; Oxides; Prognosis; Retrospective Studies; Risk Factors | 2019 |
Retained organic solutes, patient characteristics and all-cause and cardiovascular mortality in hemodialysis: results from the retained organic solutes and clinical outcomes (ROSCO) investigators.
Topics: Adult; Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Female; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis; Treatment Outcome | 2013 |
Gastrointestinal-related uremic toxins in peritoneal dialysis: a pilot study with a 5-year follow-up.
Topics: Adult; Cardiovascular Diseases; Cresols; Female; Follow-Up Studies; Humans; Indican; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Pilot Projects; Prognosis; Sulfuric Acid Esters | 2013 |
Effects of AST-120 on blood concentrations of protein-bound uremic toxins and biomarkers of cardiovascular risk in chronic dialysis patients.
Topics: Adsorption; Adult; Biomarkers; Carbon; Cardiovascular Diseases; Cresols; Cytokine TWEAK; Female; Humans; Indican; Interleukin-6; Kidney Failure, Chronic; Male; Malondialdehyde; Middle Aged; Oxides; Protein Binding; Renal Dialysis; Risk Factors; Sulfuric Acid Esters; Tumor Necrosis Factors; Uremia | 2014 |
Protein-bound uremic toxins, inflammation and oxidative stress: a cross-sectional study in stage 3-4 chronic kidney disease.
Topics: Aged; Antioxidants; Biomarkers; Blood Proteins; Cardiovascular Diseases; Cresols; Cross-Sectional Studies; Female; Humans; Indican; Inflammation; Interleukin-6; Male; Middle Aged; Oxidative Stress; Renal Insufficiency, Chronic; Risk Reduction Behavior; Sulfuric Acid Esters; Toxins, Biological; Uremia; Vascular Stiffness | 2014 |
Protein-bound molecules: a large family with a bad character.
Topics: Cardiovascular Diseases; Cognition Disorders; Cresols; Humans; Indican; Kidney Diseases; Protein Binding; Sulfuric Acid Esters | 2014 |
Heritability and clinical determinants of serum indoxyl sulfate and p-cresyl sulfate, candidate biomarkers of the human microbiome enterotype.
Topics: Adult; Biomarkers; Cardiovascular Diseases; Cresols; Cross-Sectional Studies; Diet; Female; Humans; Indican; Male; Microbiota; Middle Aged; Sulfuric Acid Esters; Young Adult | 2014 |
Uraemic toxins and cardiovascular disease across the chronic kidney disease spectrum: an observational study.
Topics: Aged; Biomarkers; Brachial Artery; Cardiovascular Diseases; Carotid Intima-Media Thickness; Cresols; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Indican; Kidney Failure, Chronic; Logistic Models; Male; Middle Aged; Multivariate Analysis; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors; Sulfuric Acid Esters; Vascular Stiffness | 2014 |
Free Levels of Selected Organic Solutes and Cardiovascular Morbidity and Mortality in Hemodialysis Patients: Results from the Retained Organic Solutes and Clinical Outcomes (ROSCO) Investigators.
Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Cause of Death; Cresols; Female; Glutamine; Hippurates; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Morbidity; Mortality; Patient Outcome Assessment; Renal Dialysis; Sulfuric Acid Esters; United States | 2015 |
Deleterious vascular effects of indoxyl sulfate and reversal by oral adsorbent AST-120.
Topics: Administration, Oral; Adsorption; Animals; Aorta; Apolipoproteins E; Blood Pressure; Carbon; Cardiovascular Diseases; Cell Survival; Echocardiography; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Indican; Intercellular Adhesion Molecule-1; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxides; Pulse Wave Analysis; Renal Insufficiency, Chronic; Uremia; Vascular Cell Adhesion Molecule-1 | 2015 |
Grape seed proanthocyanidin extract protects human umbilical vein endothelial cells from indoxyl sulfate-induced injury via ameliorating mitochondrial dysfunction.
Topics: Antigens, CD; Apoptosis; Cadherins; Cardiovascular Diseases; Drug Evaluation, Preclinical; Endothelial Cells; Grape Seed Extract; Human Umbilical Vein Endothelial Cells; Humans; Indican; Mitochondria; Nitric Oxide Synthase Type III; Phytotherapy; Proanthocyanidins; Reactive Oxygen Species; Renal Insufficiency, Chronic; Vitis | 2016 |
Low Dentin Matrix Protein 1 Is Associated With Incident Cardiovascular Events in Peritoneal Dialysis Patients.
Topics: Animals; Cardiovascular Diseases; Case-Control Studies; Cell Line; Extracellular Matrix Proteins; Female; Humans; Incidence; Indican; Kaplan-Meier Estimate; Logistic Models; Male; Mice; Middle Aged; Osteocytes; Peritoneal Dialysis; Phosphoproteins; Proportional Hazards Models; Risk Factors; RNA, Messenger; Vascular Calcification | 2016 |
Independent and incremental prognostic value of novel cardiac biomarkers in chronic hemodialysis patients.
Topics: Aged; Biomarkers; Cardiovascular Diseases; Cause of Death; Female; Galectin 3; Humans; Indican; Interleukin-1 Receptor-Like 1 Protein; Kidney Failure, Chronic; Male; Middle Aged; Mortality; Natriuretic Peptide, Brain; Peptide Fragments; Prognosis; Prospective Studies; Renal Dialysis; Risk Factors; ROC Curve; Stroke Volume | 2016 |
Microbial Modulation of a Uremic Toxin.
Topics: Animals; Bacteria; Bacterial Toxins; Biological Evolution; Cardiovascular Diseases; Diet; Gastrointestinal Microbiome; Humans; Indican; Kidney; Liver; Symbiosis; Tryptophanase; Uremia | 2016 |
Indoxyl sulfate - the uremic toxin linking hemostatic system disturbances with the prevalence of cardiovascular disease in patients with chronic kidney disease.
Topics: Adult; Aged; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Female; Hemostasis; Humans; Hydrogen Peroxide; Indican; Inflammation; Intercellular Adhesion Molecule-1; Lipoproteins; Male; Middle Aged; Neopterin; Oxidative Stress; Peptide Fragments; Plasminogen Activator Inhibitor 1; Prevalence; Prothrombin; Renal Insufficiency, Chronic; Thrombin; Thromboplastin; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator; Vascular Cell Adhesion Molecule-1; von Willebrand Factor | 2017 |
Indoxyl sulfate promotes proliferation of human aortic smooth muscle cells by inducing oxidative stress.
Topics: Antioxidants; Aortic Valve Stenosis; Cardiovascular Diseases; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Indican; Kidney Failure, Chronic; Muscle, Smooth, Vascular; Oxidative Stress | 2009 |
Role of oxidative stress and indoxyl sulfate in progression of cardiovascular disease in chronic kidney disease.
Topics: Animals; Carbon; Cardiovascular Diseases; Chronic Disease; Disease Progression; Drug Delivery Systems; Humans; Indican; Kidney Diseases; Oxidative Stress; Oxides; Uremia | 2011 |
New insight into the redox properties of uremic solute indoxyl sulfate as a pro- and anti-oxidant.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Chronic Disease; Humans; Indican; Kidney Diseases; Oxidants; Oxidation-Reduction; Oxidative Stress; Uremia | 2011 |
Role of indoxyl sulfate in the progression of chronic kidney disease and cardiovascular disease: experimental and clinical effects of oral sorbent AST-120.
Topics: Animals; Carbon; Cardiovascular Diseases; Chronic Disease; Disease Progression; Humans; Indican; Kidney Diseases; Oxidative Stress; Oxides; Protein Binding; Rats; Uremia | 2011 |
Indoxyl sulfate predicts cardiovascular disease and renal function deterioration in advanced chronic kidney disease.
Topics: Adult; Biomarkers; Cardiovascular Diseases; Female; Humans; Indican; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Multivariate Analysis | 2012 |
A novel UPLC-MS-MS method for simultaneous determination of seven uremic retention toxins with cardiovascular relevance in chronic kidney disease patients.
Topics: Cardiovascular Diseases; Case-Control Studies; Chromatography, High Pressure Liquid; Cresols; Female; Furans; Glucuronides; Hippurates; Humans; Indican; Indoleacetic Acids; Male; Propionates; Renal Insufficiency, Chronic; Severity of Illness Index; Sulfuric Acid Esters; Tandem Mass Spectrometry; Uremia; Uric Acid | 2013 |
Reduction of indoxyl sulfate by AST-120 attenuates monocyte inflammation related to chronic kidney disease.
Topics: Animals; Carbon; Cardiovascular Diseases; Cell Line; Disease Models, Animal; Flow Cytometry; Gastrointestinal Agents; Humans; Immunoblotting; Indican; Inflammation; Male; Mice; Mice, Inbred C57BL; Monocytes; Oxides; Reactive Oxygen Species; Renal Insufficiency, Chronic | 2013 |