indican has been researched along with Acute Kidney Injury in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.45) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 16 (51.61) | 24.3611 |
| 2020's | 10 (32.26) | 2.80 |
| Authors | Studies |
|---|---|
| Chao, CT; Chen, JH; Chiang, CK; Huang, JW; Hung, KY; Liu, SH; Tarng, DC | 1 |
| Donouchi, M; Kamada, S; Kanda, M; Kobuchi, S; Matsumura, Y; Nakagawa, K; Ohkita, M; Tanaka, R; Tawa, M | 1 |
| Mair, RD; Meyer, TW; O'Brien, FJ; Plummer, NS; Sirich, TL; Sutherland, SM | 1 |
| Berry, B; Bowles, T; Griffin, A; Spencer, SK; Wallace, K | 1 |
| Chai, Y; Huang, X; Jiang, Z; Kou, S; Li, X; Ma, Y; Qian, Y; Sun, L; Yuan, W; Zhang, L | 1 |
| Jo, SK; Kim, JY; Kim, S; Kim, YJ; Lee, I; Lee, TH; Oh, CT; Park, D; Yang, J | 1 |
| André, C; Bennis, Y; Bodeau, S; Caillard, P; Choukroun, G; Cluet, Y; Kamel, S; Liabeuf, S; Maizel, J; Titeca-Beauport, D | 1 |
| Al Salam, S; Al Suleimani, Y; Al Za'abi, M; Ali, BH; Ashique, M; Manoj, P; Nemmar, A | 1 |
| Gunda, N; Hou, H; Jono, H; Narita, Y; Saito, H; Yabuuchi, N | 1 |
| Ashizawa, N; Chikamatsu, N; Iwanaga, T; Motoki, K; Omura, K; Sakai, M; Takada, T; Taniguchi, T | 1 |
| Chen, HF; Chou, YH; Huang, HP; Hung, SC; Sheen, JF; Shen, WC | 1 |
| Glorieux, G; Liabeuf, S; Massy, ZA; Van Biesen, W; Vanholder, R; Vanmassenhove, J; Veldeman, L | 1 |
| Ding, F; Hao, G; Ma, S; Pan, Y; Ruan, H; Shi, P; Wang, W; Xie, Y; Yang, T; Zhang, Q; Zhu, Q | 1 |
| Hanouneh, M; Jaar, BG; Menez, S; Shafi, T | 1 |
| Chang, FC; Chen, JB; Chen, JH; Chen, JW; Chen, YL; Chen, YM; Huang, PH; Huang, TM; Ko, WJ; Kuo, YS; Liang, CJ; Lo, SC; Sun, CY; Wang, KC; Wu, KD; Wu, VC; Young, GH | 1 |
| Horinouchi, A; Minami, K; Morikawa, Y; Ohno, Y; Ono, A; Tonomura, Y; Uehara, T; Urushidani, T; Yamada, H; Yamate, J | 1 |
| Chuman, E; Jono, H; Komori, M; Nishi, K; Nomura, Y; Sagata, M; Saigo, C; Saito, H; Wakida, A; Yamamoto, Y; Yoshimura, M | 1 |
| Jono, H; Matsunaga, R; Nishi, K; Nomura, Y; Sagata, M; Saigo, C; Saito, H; Yamamoto, Y | 1 |
| Chen, YL; Huang, TM; Liang, CJ; Liu, CW; Peng, YS; Shen, WC; Tsai, JS; Tseng, YC; Wang, SH; Wu, VC; Young, GH | 1 |
| Bi, KS; Chen, XH; Gu, L; Shi, H; Wei, Z; Zhang, R | 1 |
| Fujino, R; Jono, H; Nishi, K; Nomura, Y; Sagata, M; Saigo, C; Saito, H; Yabuuchi, N; Yamamoto, Y; Yoneda, G | 1 |
| Anraku, M; Hirayama, F; Ifuku, S; Iohara, D; Maruyama, T; Miyamura, S; Nagae, T; Otagiri, M; Tabuchi, R; Tomida, H; Uekama, K | 1 |
| Alexander, DC; Alton, KB; Chowdhury, S; Milburn, MV; Wirth, M; Zgoda-Pols, JR | 1 |
| Adijiang, A; Bolati, D; Dateki, M; Enomoto, A; Muteliefu, G; Nishijima, F; Niwa, T; Shimizu, H | 1 |
| Hamada, A; Kamobayashi, H; Kohda, Y; Komori, M; Kusumoto, M; Saito, H; Sato, D; Tomita, K; Yoshimura, M | 1 |
| Nishijima, F; Niwa, T; Shimizu, H; Yisireyili, M | 1 |
| Fong, PD; Hostetter, TH; Martinez, AW; Meyer, TW; Pagtalunan, ME; Recht, NS; Robertson, CR; Torkamani, A; Walther, JL | 1 |
| Hamada, A; Inui, K; Kohda, Y; Matsuzaki, T; Morisaki, T; Nonoguchi, H; Saito, H; Tomita, K; Watanabe, H; Yoshitome, K | 1 |
| Hamada, A; Iwata, K; Matsuzaki, T; Morisaki, T; Ohmura, T; Saito, H; Watanabe, H | 1 |
| Goto, S; Ikeda, K; Kimura, T; Nakayama, T; Yoshitomi, H | 1 |
| Jensen, OM | 1 |
31 other study(ies) available for indican and Acute Kidney Injury
| Article | Year |
|---|---|
Early elimination of uremic toxin ameliorates AKI-to-CKD transition.
Topics: Acute Kidney Injury; Animals; Butylamines; Carbon; Drug Evaluation, Preclinical; Indican; Mice, Inbred C57BL; Nephrosclerosis; Oxides; Renal Insufficiency, Chronic; Reperfusion Injury; Senescence-Associated Secretory Phenotype; Unfolded Protein Response | 2021 |
Vascular Endothelial Dysfunction in the Thoracic Aorta of Rats with Ischemic Acute Kidney Injury: Contribution of Indoxyl Sulfate.
Topics: Acute Kidney Injury; Animals; Aorta, Thoracic; Carbon; Disease Models, Animal; Disease Progression; Endothelial Cells; Endothelium, Vascular; Indican; Ischemia; Male; Nitric Oxide; Oxides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recovery of Function; Renal Insufficiency, Chronic; Reperfusion Injury; Signal Transduction | 2022 |
Impaired Tubular Secretion of Organic Solutes in Acute Kidney Injury.
Topics: Acute Kidney Injury; Creatinine; Glomerular Filtration Rate; Humans; Indican; Kidney | 2020 |
Indoxyl Sulfate Administration during Pregnancy Contributes to Renal Injury and Increased Blood-Brain Barrier Permeability.
Topics: Acute Kidney Injury; Animals; Blood-Brain Barrier; Female; Indican; Kidney; Permeability; Pregnancy; Rats; Rats, Sprague-Dawley | 2023 |
Hyperoside ameliorates cisplatin-induced acute kidney injury by regulating the expression and function of Oat1.
Topics: Acute Kidney Injury; Animals; Cisplatin; Indican; Kidney; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Rats | 2023 |
Lactobacillus salivarius BP121 prevents cisplatin‑induced acute kidney injury by inhibition of uremic toxins such as indoxyl sulfate and p‑cresol sulfate via alleviating dysbiosis.
Topics: Acute Kidney Injury; Animals; Caco-2 Cells; Cisplatin; Cresols; Dysbiosis; Gastrointestinal Microbiome; Humans; Indican; Ligilactobacillus salivarius; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sulfuric Acid Esters | 2020 |
Two rapid, accurate liquid chromatography tandem mass spectrometry methods for the quantification of seven uremic toxins: An application for describing their accumulation kinetic profile in a context of acute kidney injury.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Biomarkers; Chromatography, Liquid; Cresols; Female; Furans; Hippurates; Humans; Indican; Limit of Detection; Linear Models; Male; Middle Aged; Propionates; Reproducibility of Results; Tandem Mass Spectrometry | 2020 |
Effects of repeated increasing doses of cisplatin as models of acute kidney injury and chronic kidney disease in rats.
Topics: Acute Kidney Injury; Albuminuria; Animals; Antineoplastic Agents; Caspase 3; Cisplatin; Creatinine; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Acid-Binding Proteins; Indican; Kidney; Male; NF-E2-Related Factor 2; Phosphorus; Rats, Wistar; Renal Insufficiency, Chronic; Urea; Uric Acid | 2021 |
Suppressed Hepatic Production of Indoxyl Sulfate Attenuates Cisplatin-Induced Acute Kidney Injury in Sulfotransferase 1a1-Deficient Mice.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Arylsulfotransferase; Cell Line; Cisplatin; Humans; Indican; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Reactive Oxygen Species | 2021 |
Hypouricemic agents reduce indoxyl sulfate excretion by inhibiting the renal transporters OAT1/3 and ABCG2.
Topics: Acute Kidney Injury; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Indican; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Wistar; Uricosuric Agents | 2021 |
Induced pluripotent stem cell-derived endothelial progenitor cells attenuate ischemic acute kidney injury and cardiac dysfunction.
Topics: Acute Kidney Injury; Animals; Apoptosis; Azotemia; Capillaries; Creatinine; Endothelial Progenitor Cells; Heart; Humans; Indican; Induced Pluripotent Stem Cells; Inflammation; Interleukin-1beta; Ischemia; Kidney Tubules; Male; Mice, Inbred NOD; Mice, SCID; Myocytes, Cardiac; Neovascularization, Physiologic | 2018 |
Evolution of protein-bound uremic toxins indoxyl sulphate and p-cresyl sulphate in acute kidney injury.
Topics: Acute Kidney Injury; Aged; Belgium; Correlation of Data; Creatinine; Cresols; Female; Humans; Indican; Male; Middle Aged; Sepsis; Sulfuric Acid Esters; Time Factors; Uremia | 2019 |
Serum indoxyl sulfate is associated with mortality in hospital-acquired acute kidney injury: a prospective cohort study.
Topics: Acute Kidney Injury; China; Critical Illness; Female; Hospital Mortality; Hospitalization; Humans; Indican; Kidney Function Tests; Male; Middle Aged; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Renal Dialysis; Risk Factors | 2019 |
Indoxyl sulfate is associated with mortality after AKI - more evidence needed!
Topics: Acute Kidney Injury; Creatinine; Humans; Indican; Prealbumin; Renal Dialysis | 2019 |
In acute kidney injury, indoxyl sulfate impairs human endothelial progenitor cells: modulation by statin.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Animals; Apoptosis; Atorvastatin; Blotting, Western; Centrifugation, Density Gradient; Endothelial Cells; Female; Flow Cytometry; Gene Expression Regulation; Heptanoic Acids; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Indican; Male; Mice; Mice, Inbred C57BL; Middle Aged; Nitric Oxide Synthase Type III; Pyrroles; Reactive Oxygen Species; Stem Cells; Taiwan; Vascular Cell Adhesion Molecule-1 | 2013 |
Identification of metabolomic biomarkers for drug-induced acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Biomarkers; Creatinine; Endpoint Determination; False Positive Reactions; Guanidine; Indican; Male; Metabolomics; Methylhistidines; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2014 |
Hepatic sulfotransferase as a nephropreventing target by suppression of the uremic toxin indoxyl sulfate accumulation in ischemic acute kidney injury.
Topics: Acute Kidney Injury; Animals; Blotting, Western; Carbon; Cell Line; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Humans; Indican; Isothiocyanates; Lipid Peroxidation; Liver; Male; NF-E2-Related Factor 2; Oxides; Quercetin; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Sulfotransferases; Sulfoxides | 2014 |
Meclofenamate elicits a nephropreventing effect in a rat model of ischemic acute kidney injury by suppressing indoxyl sulfate production and restoring renal organic anion transporters.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Down-Regulation; Indican; Inhibitory Concentration 50; Liver; Male; Meclofenamic Acid; Organic Anion Transporters; Polyphenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2014 |
Indoxyl sulfate enhances IL-1β-induced E-selectin expression in endothelial cells in acute kidney injury by the ROS/MAPKs/NFκB/AP-1 pathway.
Topics: Acute Kidney Injury; Aged; Animals; Biomarkers; Cells, Cultured; Disease Models, Animal; E-Selectin; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Indican; Interleukin-1beta; Kidney; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Oxidative Stress; Poisons; Reperfusion Injury; Up-Regulation; Uremia | 2016 |
Simultaneous Determination of Five Specific and Sensitive Nephrotoxicity Biomarkers in Serum and Urine Samples of Four Drug-Induced Kidney Injury Models.
Topics: Acute Kidney Injury; Animals; Biomarkers; Creatinine; Glycine; Hippurates; Indican; Kidney; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; ROC Curve; Sensitivity and Specificity; Uric Acid | 2017 |
Indoxyl Sulfate as a Mediator Involved in Dysregulation of Pulmonary Aquaporin-5 in Acute Lung Injury Caused by Acute Kidney Injury.
Topics: Acute Kidney Injury; Acute Lung Injury; Animals; Aquaporin 5; Indican; Lung; Male; Rats; Rats, Sprague-Dawley | 2016 |
An oral absorbent, surface-deacetylated chitin nano-fiber ameliorates renal injury and oxidative stress in 5/6 nephrectomized rats.
Topics: Acetylation; Acute Kidney Injury; Administration, Oral; Animals; Carbon; Chitin; Indican; Kidney; Nanofibers; Nephrectomy; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2017 |
Metabolomics analysis reveals elevation of 3-indoxyl sulfate in plasma and brain during chemically-induced acute kidney injury in mice: investigation of nicotinic acid receptor agonists.
Topics: Acute Kidney Injury; Animals; Biomarkers; Brain; Indican; Kidney; Male; Metabolomics; Mice; Nicotinic Agonists; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent | 2011 |
NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells.
Topics: Actins; Acute Kidney Injury; Animals; Benzothiazoles; beta-Galactosidase; Cell Line; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Humans; Indican; Kidney Tubules, Proximal; Male; NF-kappa B; Promoter Regions, Genetic; Pyrrolidines; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Sesquiterpenes; Thiocarbamates; Toluene; Transforming Growth Factor beta1; Tumor Suppressor Protein p53 | 2011 |
Alleviation of cisplatin-induced acute kidney injury using phytochemical polyphenols is accompanied by reduced accumulation of indoxyl sulfate in rats.
Topics: Acute Kidney Injury; Administration, Oral; Animals; Antineoplastic Agents; Biomarkers; Blood Urea Nitrogen; Body Weight; Cell Adhesion Molecules; Cisplatin; Creatinine; Disease Models, Animal; Indican; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Polyphenols; Quercetin; Rats; Rats, Sprague-Dawley; Time Factors | 2011 |
Stat3 contributes to indoxyl sulfate-induced inflammatory and fibrotic gene expression and cellular senescence.
Topics: Acute Kidney Injury; Animals; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Fibrosis; Gene Expression; Humans; Indican; Kidney Tubules, Proximal; Male; Nephrectomy; Phosphorylation; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; STAT3 Transcription Factor; Uremia | 2012 |
The clearance of protein-bound solutes by hemofiltration and hemodiafiltration.
Topics: Acute Kidney Injury; Hemodiafiltration; Hemofiltration; Humans; In Vitro Techniques; Indican; Indicators and Reagents; Models, Theoretical; Phenolsulfonphthalein; Protein Binding; Proteins; Solutions; Urea | 2005 |
Downregulation of organic anion transporters in rat kidney under ischemia/reperfusion-induced acute [corrected] renal failure.
Topics: Acute Kidney Injury; Animals; Cobalt; Down-Regulation; Estrone; Indican; Kidney; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Trace Elements | 2007 |
Involvement of indoxyl sulfate in renal and central nervous system toxicities during cisplatin-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Blood Urea Nitrogen; Body Temperature; Body Weight; Brain; Carbon; Cell Cycle Proteins; Central Nervous System Diseases; Circadian Rhythm; Cisplatin; Creatinine; Disease Models, Animal; Gastrointestinal Agents; Gene Expression; Indican; Kidney; Kidney Function Tests; Male; Nuclear Proteins; Oxides; Period Circadian Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Suprachiasmatic Nucleus; Time Factors | 2007 |
Plasma protein binding of frusemide in renal failure rabbits: investigation of endogenous protein binding inhibitors.
Topics: Acute Kidney Injury; Animals; Blood Proteins; Chromatography, Gel; Chromatography, High Pressure Liquid; Furosemide; Indican; Indoleacetic Acids; Indoles; Male; Mercuric Chloride; Molecular Weight; Protein Binding; Rabbits; Serum Albumin, Bovine | 1984 |
Diagnosis of uraemia post mortem.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Autopsy; Blood Chemical Analysis; Cerebrospinal Fluid; Child; Child, Preschool; Creatinine; Female; Humans; Indican; Infant; Kidney Failure, Chronic; Male; Middle Aged; Postmortem Changes; Sulfates; Urea; Uremia; Urine | 1969 |