indibulin and Breast Cancer studies

indibulin and Breast Cancer

indibulin has been researched along with Breast Cancer in 2 studies

indibulin: Tubulin Modulator/Antineoplastic Agent; structure in first source

Research Excerpts

Excerpt	Relevance	Reference
"Indibulin treatment also perturbed the localization of end-binding proteins at the growing microtubule ends in MCF-7 cells."	1.48	Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. ( Kapoor, S; Panda, D; Srivastava, S, 2018)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

2 (100.00)

24.3611

2020's

0 (0.00)

2.80

Authors	Studies
Kapoor, S	1
Srivastava, S	1
Panda, D	1
Saeedian Moghadam, E	1
Hamel, E	1
Shahsavari, Z	1
Amini, M	1

Authors

Studies

Kapoor, S

Srivastava, S

Panda, D

Saeedian Moghadam, E

Hamel, E

Shahsavari, Z

Amini, M

Clinical Trials (6)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
Dose-finding and Pharmacokinetic Trial of Orally Administered D-24851 to Patients With Solid Tumors[NCT00591136]	Phase 1	47 participants (Actual)	Interventional	2003-04-30	Completed
IBL1002:Phase I Study of Indibulin in Advanced Solid Tumors[NCT00591292]	Phase 1	22 participants (Actual)	Interventional	2007-06-30	Active, not recruiting
Phase I Study of Indibulin in Combination With Erlotinib in Advanced Solid Tumors[NCT00591383]	Phase 1	10 participants (Actual)	Interventional	2008-01-31	Active, not recruiting
Phase 1b Study of Indibulin in Combination With Capecitabine in Advanced Solid Tumors[NCT00726687]	Phase 1/Phase 2	7 participants (Actual)	Interventional	2008-06-30	Active, not recruiting
Phase IB Study to Evaluate the Biological Activity of Indibulin Using Positron-Emission Tomography (PET) Scans[NCT00591890]	Phase 1	20 participants (Actual)	Interventional	2007-10-31	Completed
Phase I/II Study of a Novel Indibulin Dosing Schedule for the Treatment of Metastatic Breast Cancer[NCT01113970]	Phase 1/Phase 2	60 participants (Anticipated)	Interventional	2010-03-31	Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

Dose-finding and Pharmacokinetic Trial of Orally Administered D-24851 to Patients With Solid Tumors[NCT00591136]

Phase 1

47 participants (Actual)

Interventional

2003-04-30

Completed

IBL1002:Phase I Study of Indibulin in Advanced Solid Tumors[NCT00591292]

Phase 1

22 participants (Actual)

Interventional

2007-06-30

Active, not recruiting

Phase I Study of Indibulin in Combination With Erlotinib in Advanced Solid Tumors[NCT00591383]

Phase 1

10 participants (Actual)

Interventional

2008-01-31

Active, not recruiting

Phase 1b Study of Indibulin in Combination With Capecitabine in Advanced Solid Tumors[NCT00726687]

Phase 1/Phase 2

7 participants (Actual)

Interventional

2008-06-30

Active, not recruiting

Phase IB Study to Evaluate the Biological Activity of Indibulin Using Positron-Emission Tomography (PET) Scans[NCT00591890]

Phase 1

20 participants (Actual)

Interventional

2007-10-31

Completed

Phase I/II Study of a Novel Indibulin Dosing Schedule for the Treatment of Metastatic Breast Cancer[NCT01113970]

Phase 1/Phase 2

60 participants (Anticipated)

Interventional

2010-03-31

Active, not recruiting

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for indibulin and Breast Cancer

Article	Year
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy. Scientific reports, 2018, 08-17, Volume: 8, Issue:1 Topics: Acetamides; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Differentiation; Female; Human	2018
Synthesis and anti-breast cancer activity of novel indibulin related diarylpyrrole derivatives. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2019, Volume: 27, Issue:1 Topics: Acetamides; Animals; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Female; Humans;	2019

Article

Year

Indibulin dampens microtubule dynamics and produces synergistic antiproliferative effect with vinblastine in MCF-7 cells: Implications in cancer chemotherapy.