indeloxazine has been researched along with Disease Models, Animal in 3 studies
indeloxazine: RN given refers to parent cpd without isomeric designation
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adjuvant-induced arthritis (AIA) and bradykinin-induced knee joint pain were used as rat models of inflammatory pain." | 7.81 | AS1069562, the (+)-isomer of indeloxazine, exerts analgesic effects in rat models of nociceptive pain. ( Aoki, T; Irie, M; Matsuoka, N; Murai, N; Nishigaki, F; Takeshita, N; Tamura, S, 2015) |
| " Here, we investigated the relationship between SERT occupancies and the analgesic effects of AS1069562, the (+)-isomer of indeloxazine, and duloxetine, which are both 5-HT and NE reuptake inhibitors (SNRIs), on muscular pain in reserpine-induced myalgia (RIM) rats, an animal model of FM-like chronic pain." | 7.81 | Relationship between serotonin transporter occupancies and analgesic effects of AS1069562, the (+)-isomer of indeloxazine, and duloxetine in reserpine-induced myalgia rats. ( Aoki, T; Fushiki, H; Honda, S; Irie, M; Iwashita, A; Murai, N; Murakami, Y; Nagakura, Y; Tamura, S, 2015) |
| "Adjuvant-induced arthritis (AIA) and bradykinin-induced knee joint pain were used as rat models of inflammatory pain." | 3.81 | AS1069562, the (+)-isomer of indeloxazine, exerts analgesic effects in rat models of nociceptive pain. ( Aoki, T; Irie, M; Matsuoka, N; Murai, N; Nishigaki, F; Takeshita, N; Tamura, S, 2015) |
| " Here, we investigated the relationship between SERT occupancies and the analgesic effects of AS1069562, the (+)-isomer of indeloxazine, and duloxetine, which are both 5-HT and NE reuptake inhibitors (SNRIs), on muscular pain in reserpine-induced myalgia (RIM) rats, an animal model of FM-like chronic pain." | 3.81 | Relationship between serotonin transporter occupancies and analgesic effects of AS1069562, the (+)-isomer of indeloxazine, and duloxetine in reserpine-induced myalgia rats. ( Aoki, T; Fushiki, H; Honda, S; Irie, M; Iwashita, A; Murai, N; Murakami, Y; Nagakura, Y; Tamura, S, 2015) |
| "In the PGE2-induced allodynia model, AS1069562 and duloxetine significantly suppressed allodynia, whereas amitriptyline did not." | 1.40 | Antinociceptive effects of AS1069562, the (+)-isomer of indeloxazine, on spinal hypersensitivity induced by intrathecal injection of prostaglandin in mice: comparison with duloxetine and amitriptyline. ( Aoki, T; Matsuoka, N; Murai, N; Tamura, S; Tsukamoto, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murai, N | 3 |
| Tsukamoto, M | 1 |
| Tamura, S | 3 |
| Aoki, T | 3 |
| Matsuoka, N | 2 |
| Takeshita, N | 1 |
| Nishigaki, F | 1 |
| Irie, M | 2 |
| Fushiki, H | 1 |
| Honda, S | 1 |
| Murakami, Y | 1 |
| Iwashita, A | 1 |
| Nagakura, Y | 1 |
3 other studies available for indeloxazine and Disease Models, Animal
| Article | Year |
|---|---|
Antinociceptive effects of AS1069562, the (+)-isomer of indeloxazine, on spinal hypersensitivity induced by intrathecal injection of prostaglandin in mice: comparison with duloxetine and amitriptyline.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Disease Models, Animal; Dose-Response Rel | 2014 |
AS1069562, the (+)-isomer of indeloxazine, exerts analgesic effects in rat models of nociceptive pain.
Topics: Analgesics; Animals; Arthralgia; Arthritis, Experimental; Bradykinin; Chronic Disease; Disease Model | 2015 |
Relationship between serotonin transporter occupancies and analgesic effects of AS1069562, the (+)-isomer of indeloxazine, and duloxetine in reserpine-induced myalgia rats.
Topics: Analgesics; Animals; Brain; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; | 2015 |