Compounds > indazoles
Page last updated: 2024-08-21

indazoles and Skin Neoplasms

indazoles has been researched along with Skin Neoplasms in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.25)18.7374
1990's0 (0.00)18.2507
2000's1 (3.13)29.6817
2010's23 (71.88)24.3611
2020's6 (18.75)2.80

Authors

AuthorsStudies
Balgetir, F; Er, MB; Gonen, M; Yildirim, N1
Fujiwara, S; Nakamura, K; Nakano, E; Nishigori, C; Ogura, K; Washio, K1
Iwaki, Y; Kamo, R; Nakai, K; Ozawa, T; Tsuruta, D; Watanabe, M1
Maeda, T; Nakano, E; Namikawa, K; Oashi, K; Shibata, T; Takahashi, A; Teramoto, Y; Tsutsumida, A; Yamazaki, N; Yokota, K1
Distel, LV; Fietkau, R; Hecht, M; Heinzerling, L; Jost, T; Knippertz, I; Weigert, V1
Adamski, H; Battistella, M; Bertucci, F; Da Meda, L; Dalac, S; Delyon, J; Ghrieb, Z; Guillot, B; Jouary, T; Lebbe, C; Leccia, MT; Meyer, N; Mortier, L; Mourah, S; Pedeutour, F; Porcher, R; Vicaut, E1
Keam, B; Kim, DW; Kim, M; Kim, SH; Kim, TM; Kim, YJ; Kwak, Y; Moon, KC; Park, C1
Freeman, ML; Gibney, GT; Knepper, TC; McLeod, HL; Russell, JS1
Chandramohan, J; George, AA; Georgy, JT; Mathuram, AJ1
Bhatia, S; Blom, A; Nghiem, P; Olencki, T; Parvathaneni, U; Tarabadkar, ES; Thomas, H1
Adachi, A; Komine, M; Maekawa, T; Murata, S; Ohtsuki, M1
Hasunuma, N; Manabe, M; Osada, SI; Toyoshima, A; Yamada, K; Yamada, M1
Hata, H; Imafuku, K; Kitamura, S; Maeda, T; Masuzawa, M; Shimizu, H; Yanagi, T1
Näär, AM; Wu, S1
Creixell, P; Jeschke, GR; Kim, J; Linding, R; Longden, J; Poulikakos, PI; Rosen, N; Santini, CC; Schoof, EM; Simpson, CD; Turk, BE; Wu, X1
Arepalli, SK; Jung, JK; Kim, Y; Lee, C; Lee, H; Lee, K1
Bosenberg, M; De, SK; Feng, Y; Kluger, H; Lazova, R; Li, JL; Pellecchia, M; Rickert, R; Ronai, ZA; Ruller, C; Scortegagna, M1
Abe, K; Asai, M; Koike, Y; Ogawa, F; Tanioka, M; Tomita, H; Utani, A1
Chen, S; Cohen-Sola, KA; Goydos, JS; Jeong, BS; Koo, J; Li, J; Lin, Y; Mehnert, JM; Shin, SS; Wen, Y1
Aldabagh, B; Joo, J; Yu, SS1
Bosenberg, M; Brown, K; Davies, MA; De, SK; Feng, Y; Halaban, R; Langdon, CG; Lau, E; Meeth, K; Pellecchia, M; Platt, JT; Ronai, ZA; Scortegagna, M; Sereduk, C; Stern, DF; Yin, H; Zhang, T1
Miura, H; Shirai, H1
Haga, N; Hata, H; Homma, E; Imafuku, K; Kitamura, S; Shimizu, H1
Abarzúa, Á; Giesen, L; González, S; Molgó, M1
Cheng, PF; Dummer, R; Goldinger, SM; Guenova, E; Jaberg-Bentele, N; Kunz, M; Levesque, MP; Mangana, J; Nagel, HW; Nägeli, M; Thurneysen, S; Ziegler, M1
Oashi, K; Ogata, D; Suzuki, K; Tsuchida, T; Yamazaki, N; Yanagisawa, H1
Hirabayashi, M; Hoashi, T; Nakajima, R; Saeki, H; Takahashi, N1
Fujita, H; Kadono, T; Kimura, T; Masui, Y; Miyagaki, T; Miyagawa, T; Saigusa, R; Sato, S; Yamada, D; Yoshizaki, A1
Charlton, A; Chong, ML; Dar, M; Davids, M; Davids, MS; Goh, BC; Hodge, J; Laubscher, K; Ng, SS; Soong, R1
Bose, A; Lowe, DB; Rao, A; Storkus, WJ1
Battelli, T; Bellocci, M; Cavaliere, R; De Martino, C; Di Filippo, F; Gallo Curcio, C; Giustini, L; Manocchi, D; Mattioli, R; Rinaldi, M1
Ormea, F1

Reviews

2 review(s) available for indazoles and Skin Neoplasms

ArticleYear
Fatal Acute Motor Axonal Neuropathy Induced by Nivolumab: A Case Report and Literature Review.
    Clinical genitourinary cancer, 2019, Volume: 17, Issue:6

    Topics: Aged; Antineoplastic Agents, Immunological; Axons; Carcinoma, Renal Cell; Drug Substitution; Fatal Outcome; Humans; Indazoles; Kidney Neoplasms; Lymphatic Metastasis; Male; Motor Neurons; Nivolumab; Paraparesis; Polyneuropathies; Pyrimidines; Skin Neoplasms; Sulfonamides

2019
Merkel cell carcinoma: current status of targeted and future potential for immunotherapies.
    Seminars in cutaneous medicine and surgery, 2014, Volume: 33, Issue:2

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Benzamides; Biomarkers; Carcinoma, Merkel Cell; CD56 Antigen; Electrochemotherapy; Hepatitis A Virus Cellular Receptor 2; Humans; Imatinib Mesylate; Immunotherapy; Immunotherapy, Adoptive; Indazoles; Inhibitor of Apoptosis Proteins; Interferons; Interleukin-12; Interleukin-2; Ipilimumab; Lymphatic Metastasis; Membrane Proteins; Merkel cell polyomavirus; Oligonucleotides, Antisense; Piperazines; Polyomavirus Infections; Prognosis; Programmed Cell Death 1 Receptor; Pyrimidines; Receptors, Somatomedin; Skin Neoplasms; Somatostatin; Sulfonamides; Survivin; Thionucleotides; TOR Serine-Threonine Kinases

2014

Trials

2 trial(s) available for indazoles and Skin Neoplasms

ArticleYear
A Multicenter Phase II Study of Pazopanib in Patients with Unresectable Dermatofibrosarcoma Protuberans.
    The Journal of investigative dermatology, 2021, Volume: 141, Issue:4

    Topics: Adult; Aged; Biomarkers, Tumor; Dermatofibrosarcoma; Drug Resistance, Neoplasm; Epidermal Growth Factor; ErbB Receptors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Indazoles; Male; Middle Aged; Protein Kinase Inhibitors; Pyrimidines; Response Evaluation Criteria in Solid Tumors; Skin; Skin Neoplasms; Sulfonamides; Tumor Burden

2021
An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel.
    The British journal of dermatology, 2016, Volume: 175, Issue:5

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Cytokines; Drug Administration Schedule; Female; Humans; Indazoles; Infusions, Intravenous; Male; Melanoma; Paclitaxel; Pyrimidines; Skin Neoplasms; Sulfonamides; Treatment Outcome; Up-Regulation

2016

Other Studies

28 other study(ies) available for indazoles and Skin Neoplasms

ArticleYear
Pazopanib as a potential chemotherapy for cutaneous angiosarcoma: A case series of 10 patients from a single institution.
    The Journal of dermatology, 2020, Volume: 47, Issue:7

    Topics: Hemangiosarcoma; Humans; Indazoles; Pyrimidines; Skin Neoplasms; Sulfonamides

2020
Successful long-term treatment with pazopanib after prior interleukin-2 therapy in patients with metastatic cutaneous angiosarcoma of the scalp.
    Dermatologic therapy, 2020, Volume: 33, Issue:6

    Topics: Hemangiosarcoma; Humans; Indazoles; Interleukin-2; Pyrimidines; Scalp; Skin Neoplasms; Sulfonamides

2020
A single-arm confirmatory trial of pazopanib in patients with paclitaxel-pretreated primary cutaneous angiosarcoma: Japan Clinical Oncology Group study (JCOG1605, JCOG-PCAS protocol).
    BMC cancer, 2020, Jul-13, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Hemangiosarcoma; Humans; Indazoles; Male; Middle Aged; Paclitaxel; Prognosis; Pyrimidines; Research Design; Salvage Therapy; Skin Neoplasms; Sulfonamides; Young Adult

2020
PARP inhibitors combined with ionizing radiation induce different effects in melanoma cells and healthy fibroblasts.
    BMC cancer, 2020, Aug-18, Volume: 20, Issue:1

    Topics: Apoptosis; Cell Survival; Chemoradiotherapy; Drug Interactions; Fibroblasts; G2 Phase Cell Cycle Checkpoints; Homologous Recombination; Humans; Indazoles; Melanoma; Phthalazines; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Primary Cell Culture; Skin; Skin Neoplasms; Tumor Cells, Cultured

2020
Real-World Clinical Outcomes and Prognostic Factors for Patients with Advanced Angiosarcoma who Received Systemic Treatment.
    Cancer research and treatment, 2021, Volume: 53, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Follow-Up Studies; Hemangiosarcoma; Humans; Indazoles; Liver Neoplasms; Male; Middle Aged; Paclitaxel; Prognosis; Pyrimidines; Retrospective Studies; Skin Neoplasms; Sulfonamides; Survival Rate

2021
Clinical Response to Pazopanib in a Patient With KDR-Mutated Metastatic Basal Cell Carcinoma.
    JAMA dermatology, 2017, 06-01, Volume: 153, Issue:6

    Topics: Carcinoma, Basal Cell; DNA Mutational Analysis; DNA, Neoplasm; Humans; Indazoles; Male; Middle Aged; Mutation; Pyrimidines; Receptors, Vascular Endothelial Growth Factor; Skin Neoplasms; Sulfonamides; Vascular Endothelial Growth Factor Receptor-2

2017
Renal cell carcinoma presenting as a cutaneous horn and nodules on the gingiva and scalp.
    BMJ case reports, 2017, Aug-18, Volume: 2017

    Topics: Acute Kidney Injury; Angiogenesis Inhibitors; Carcinoma, Renal Cell; Diagnosis, Differential; Fatal Outcome; Gingiva; Humans; Indazoles; Kidney Neoplasms; Male; Middle Aged; Pyrimidines; Scalp; Skin Neoplasms; Sulfonamides

2017
Clinical Benefit from Tyrosine Kinase Inhibitors in Metastatic Merkel Cell Carcinoma: A Case Series of 5 Patients.
    The American journal of case reports, 2018, Apr-30, Volume: 19

    Topics: Aged; Angiogenesis Inhibitors; Anilides; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Merkel Cell; Humans; Indazoles; Male; Middle Aged; Neoplasm Metastasis; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Skin Neoplasms; Sulfonamides

2018
Long-term survival of a patient with neurofibromatosis type 1 diagnosed with multiple malignant peripheral nerve sheath tumors.
    The Journal of dermatology, 2019, Volume: 46, Issue:1

    Topics: Adult; Aged; Bone and Bones; Bone Neoplasms; Humans; Indazoles; Magnetic Resonance Imaging; Middle Aged; Neoplasms, Second Primary; Nerve Sheath Neoplasms; Neurofibromatosis 1; Pyrimidines; Radiotherapy, Adjuvant; Skin; Skin Neoplasms; Sulfonamides; Time Factors; Treatment Outcome

2019
Prevention of tumor progression in Stewart-Treves syndrome with a low dose of pazopanib.
    The Journal of dermatology, 2019, Volume: 46, Issue:7

    Topics: Aged; Amputation Stumps; Amputation, Surgical; Biopsy; Chemoradiotherapy; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hemangiosarcoma; Humans; Indazoles; Leg; Lymphangiosarcoma; Neoplasm Recurrence, Local; Progression-Free Survival; Protein Kinase Inhibitors; Pyrimidines; Skin; Skin Neoplasms; Sulfonamides

2019
Evaluation of pazopanib cytotoxicity to normal vascular endothelial cells in vitro: A comment on Goto et al.
    The Journal of dermatology, 2019, Volume: 46, Issue:9

    Topics: Angiogenesis Inhibitors; Apoptosis; Cell Line, Tumor; Cell Survival; Dermis; Endothelium, Vascular; Fibroblasts; Hemangiosarcoma; Human Umbilical Vein Endothelial Cells; Humans; Indazoles; Pyrimidines; Skin Neoplasms; Sulfonamides; Toxicity Tests

2019
SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait.
    Scientific reports, 2019, 07-17, Volume: 9, Issue:1

    Topics: Cell Line, Tumor; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Fatty Acids; Gene Expression Regulation, Neoplastic; Humans; Indazoles; Kaplan-Meier Estimate; Melanoma; Neoplasm Proteins; Neoplasms; Piperazines; Prognosis; Proto-Oncogene Proteins B-raf; RNA Interference; RNA Polymerase II; RNA, Small Interfering; Skin Neoplasms; Sterol Regulatory Element Binding Protein 1; Transcription, Genetic; Vemurafenib

2019
Global view of the RAF-MEK-ERK module and its immediate downstream effectors.
    Scientific reports, 2019, 07-26, Volume: 9, Issue:1

    Topics: Apoptosis; Cell Line, Tumor; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Indazoles; MAP Kinase Signaling System; Melanoma; Mitogen-Activated Protein Kinase Kinases; Oximes; Phosphorylation; Piperazines; Proteome; Proteomics; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; Skin Neoplasms

2019
Synthesis of N-arylindazole-3-carboxamide and N-benzoylindazole derivatives and their evaluation against α-MSH-stimulated melanogenesis.
    Bioorganic & medicinal chemistry letters, 2019, 09-15, Volume: 29, Issue:18

    Topics: alpha-MSH; Animals; Antineoplastic Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Indazoles; Melanoma, Experimental; Mice; Molecular Structure; Skin Neoplasms; Structure-Activity Relationship

2019
Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma.
    Oncogene, 2014, Aug-21, Volume: 33, Issue:34

    Topics: Animals; Carcinogenesis; Cell Line, Tumor; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Knockout Techniques; Humans; Indazoles; Lung Neoplasms; Lymphatic Metastasis; Melanoma, Experimental; Mice; Mice, Knockout; Mutation, Missense; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins B-raf; PTEN Phosphohydrolase; Pyrimidines; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Signal Transduction; Skin Neoplasms; Tissue Array Analysis

2014
Angiosarcoma of the scalp successfully treated with pazopanib.
    Journal of the American Academy of Dermatology, 2014, Volume: 70, Issue:1

    Topics: Angiogenesis Inhibitors; Head and Neck Neoplasms; Hemangiosarcoma; Humans; Indazoles; Male; Middle Aged; Pyrimidines; Scalp; Skin Neoplasms; Sulfonamides

2014
Activation of the glutamate receptor GRM1 enhances angiogenic signaling to drive melanoma progression.
    Cancer research, 2014, May-01, Volume: 74, Issue:9

    Topics: Angiogenesis Inhibitors; Animals; Cell Movement; Heterocyclic Compounds, 3-Ring; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Inhibitor of Apoptosis Proteins; Interleukin-8; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Receptors, Metabotropic Glutamate; Riluzole; Signal Transduction; Sirolimus; Skin Neoplasms; Survivin; Tumor Burden; Vascular Endothelial Growth Factor A

2014
PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets.
    Cancer research, 2015, Apr-01, Volume: 75, Issue:7

    Topics: Animals; Benzoates; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Drug Screening Assays, Antitumor; G1 Phase Cell Cycle Checkpoints; Humans; Immediate-Early Proteins; Indazoles; Lymphatic Metastasis; Melanoma; Mice, Knockout; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins B-raf; Pyrimidines; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Skin; Skin Neoplasms

2015
Low-dose administration of oral pazopanib for the treatment of recurrent angiosarcoma.
    Clinical and experimental dermatology, 2015, Volume: 40, Issue:5

    Topics: Administration, Oral; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Female; Hemangiosarcoma; Humans; Indazoles; Male; Neoplasm Recurrence, Local; Protein Kinase Inhibitors; Pyrimidines; Skin Neoplasms; Sulfonamides; Treatment Outcome

2015
Pazopanib can preserve cosmetic quality of life even in end-stage angiosarcoma.
    Clinical and experimental dermatology, 2015, Volume: 40, Issue:8

    Topics: Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents; Female; Head and Neck Neoplasms; Hemangiosarcoma; Humans; Indazoles; Protein Kinase Inhibitors; Pyrimidines; Quality of Life; Scalp; Skin Neoplasms; Sulfonamides

2015
Nasal tumoral lesion: challenge. Cutaneous metastasis of renal cell carcinoma.
    The American Journal of dermatopathology, 2015, Volume: 37, Issue:5

    Topics: Aged; Angiogenesis Inhibitors; Biomarkers, Tumor; Biopsy; Carcinoma, Renal Cell; Fatal Outcome; Humans; Immunohistochemistry; Indazoles; Kidney Neoplasms; Male; Neoplasm Recurrence, Local; Nose Neoplasms; Pyrimidines; Skin Neoplasms; Sulfonamides; Time Factors; Treatment Outcome

2015
Pazopanib treatment slows progression and stabilizes disease in patients with taxane-resistant cutaneous angiosarcoma.
    Medical oncology (Northwood, London, England), 2016, Volume: 33, Issue:10

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Bridged-Ring Compounds; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Hemangiosarcoma; Humans; Indazoles; Male; Middle Aged; Pyrimidines; Retrospective Studies; Skin Neoplasms; Sulfonamides; Taxoids

2016
Paradoxical antitumor effects of pazopanib in a cutaneous angiosarcoma patient.
    The Journal of dermatology, 2017, Volume: 44, Issue:9

    Topics: Aged; Angiogenesis Inhibitors; Disease Progression; Head and Neck Neoplasms; Hemangiosarcoma; Humans; Indazoles; Male; Pyrimidines; Skin Neoplasms; Sulfonamides

2017
Pazopanib induced a partial response in a patient with metastatic fibrosarcomatous dermatofibrosarcoma protuberans without genetic translocations resistant to mesna, doxorubicin, ifosfamide and dacarbazine chemotherapy and gemcitabine-docetaxel chemothera
    The Journal of dermatology, 2017, Volume: 44, Issue:3

    Topics: Abdomen; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Deoxycytidine; Dermatofibrosarcoma; Docetaxel; Doxorubicin; Drug Resistance, Neoplasm; Fatal Outcome; Gemcitabine; Humans; Ifosfamide; Indazoles; Male; Mesna; Middle Aged; Pyrimidines; Skin Neoplasms; Sulfonamides

2017
Response to a novel multitargeted tyrosine kinase inhibitor pazopanib in metastatic Merkel cell carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-10, Volume: 27, Issue:26

    Topics: Aged; Base Sequence; Biomarkers; Carcinoma, Merkel Cell; DNA Mutational Analysis; Fatal Outcome; Female; Humans; Indazoles; Keratins; Mutation; Neoplasm Metastasis; Phosphopyruvate Hydratase; Protein Kinase Inhibitors; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Scalp; Skin Neoplasms; Sulfonamides

2009
Combined vaccine+axitinib therapy yields superior antitumor efficacy in a murine melanoma model.
    Melanoma research, 2012, Volume: 22, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Axitinib; Cancer Vaccines; Cell Line, Tumor; Combined Modality Therapy; Dendritic Cells; Endothelial Cells; Female; Imidazoles; Indazoles; Interleukin-12; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Melanoma; Mice; Mice, Inbred C57BL; Ovalbumin; Peptide Fragments; Protein Kinase Inhibitors; Skin Neoplasms; T-Lymphocytes; Time Factors; Tumor Burden; Tumor Microenvironment

2012
Morphological damage induced in vivo by Lonidamine on human metastatic cancer cells.
    Oncology, 1984, Volume: 41 Suppl 1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Humans; Hyperthermia, Induced; Indazoles; Melanoma; Mice; Neoplasms; Pyrazoles; Skin Neoplasms

1984
[The external treatment of dermatoses (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Mar-29, Volume: 116, Issue:13

    Topics: Administration, Topical; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Dermatologic Agents; Drug Interactions; Glucocorticoids; Humans; Indazoles; Ointments; Pharmaceutical Vehicles; Precancerous Conditions; Psoriasis; Skin; Skin Absorption; Skin Diseases; Skin Neoplasms

1974